IGVFDS9875NBZW

single-nucleus RNA sequencing assay

true

GRU

/human-donors/IGVFDO2650AGWB/, /human-donors/IGVFDO2492CCQG/, /human-donors/IGVFDO1964RNHE/, /human-donors/IGVFDO2817PSCX/, /human-donors/IGVFDO4876ENMD/, /human-donors/IGVFDO4134ZWBU/, /human-donors/IGVFDO8893DMFF/, /human-donors/IGVFDO0657EMJH/, /human-donors/IGVFDO1364EAZP/, /human-donors/IGVFDO6162MIWK/, /human-donors/IGVFDO2379DTAU/, /human-donors/IGVFDO7140TLQJ/, /human-donors/IGVFDO9904ZSML/, /human-donors/IGVFDO8977PNMK/, /human-donors/IGVFDO1221XJAX/, /human-donors/IGVFDO2718IDDQ/, /human-donors/IGVFDO2965ZTUG/, /human-donors/IGVFDO0183MFIP/, /human-donors/IGVFDO7813GMND/, /human-donors/IGVFDO6169GISQ/, /human-donors/IGVFDO8129FWUV/, /human-donors/IGVFDO5261UCLF/, /human-donors/IGVFDO2620HPCX/, /human-donors/IGVFDO9617JBWJ/, /human-donors/IGVFDO4532PFAJ/, /human-donors/IGVFDO3755LIBB/, /human-donors/IGVFDO7470LCGC/, /human-donors/IGVFDO6638HIAD/, /human-donors/IGVFDO8129UUAA/, /human-donors/IGVFDO0720ONIQ/, /human-donors/IGVFDO4001VEAC/, /human-donors/IGVFDO5614PTYQ/, /human-donors/IGVFDO5729MXSO/, /human-donors/IGVFDO0324ZSAY/, /human-donors/IGVFDO7670TOWV/, /human-donors/IGVFDO8315PGTI/, /human-donors/IGVFDO5656YCPC/, /human-donors/IGVFDO9716HDYX/, /human-donors/IGVFDO7725MEWB/, /human-donors/IGVFDO7650ICPB/, /human-donors/IGVFDO1038DAII/, /human-donors/IGVFDO6441FSJH/, /human-donors/IGVFDO4452ZQSF/, /human-donors/IGVFDO2750DZPB/

reads, seqspec

experimental data

10x multiome with MULTI-seq

multiplexed sample: Homo sapiens (mixed sex) induced pluripotent stem differentiated cell specimen induced to islet of Langerhans for 11 days; Homo sapiens (mixed sex) induced pluripotent stem differentiated cell specimen induced to islet of Langerhans for 3 days; ... and 6 more samples

released

single-nucleus RNA sequencing assay (10x multiome with MULTI-seq)

fff841a3-91e6-4773-a75d-9eab106c3723

IGVFDS6464SOVZ

in vitro CRISPR screen using flow cytometry

no certificate

reads

experimental data

CRISPR FACS screen

Homo sapiens (male) HepG2 cell line (sorting details: Sorted for Bottom 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)

released

CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide

ffe00f40-ac0d-4488-a686-3882394fe80d

IGVFDS5414UFNC

single-nucleus ATAC-seq

false

No limitations

/human-donors/IGVFDO3971UIZC/, /human-donors/IGVFDO4053HEKW/, /human-donors/IGVFDO0909BNTN/, /human-donors/IGVFDO7754VJKM/, /human-donors/IGVFDO5912PIZP/, /human-donors/IGVFDO2928PSUK/, /human-donors/IGVFDO8670MHXE/, /human-donors/IGVFDO4191KJBR/, /human-donors/IGVFDO2045AFUW/, /human-donors/IGVFDO4103FHPT/, /human-donors/IGVFDO4108VCBA/, /human-donors/IGVFDO7095OCLJ/

reads

experimental data

10x multiome

multiplexed sample: Homo sapiens (female, 83 years) substantia nigra tissue associated with Parkinson's disease, cerebral amyloid angiopathy, mild cognitive impairment; Homo sapiens (male, 78 years) posterior cingulate gyrus tissue associated with Parkinson's disease; ... and 10 more samples

preview

single-nucleus ATAC-seq (10x multiome)

ffdd4c54-4e93-4a82-b989-86ae6b5d0528

IGVFDS3222WCZH

no certificate

8 cube mouse founder strains plate igvf_008b Subpool_3 with Gonads as the primary tissue and Adrenal gland as the genetically multiplexed tissue

/rodent-donors/IGVFDO5183UZGS/, /rodent-donors/IGVFDO6112GRYR/, /rodent-donors/IGVFDO9560CEGZ/, /rodent-donors/IGVFDO0430HQIU/, /rodent-donors/IGVFDO6141KSSQ/, /rodent-donors/IGVFDO5539RLXJ/, /rodent-donors/IGVFDO9890MXGN/, /rodent-donors/IGVFDO0026YRCR/, /rodent-donors/IGVFDO1477BPVO/, /rodent-donors/IGVFDO8904OIIT/, /rodent-donors/IGVFDO3436ZMLY/, /rodent-donors/IGVFDO6607QZPA/, /rodent-donors/IGVFDO3207TERA/, /rodent-donors/IGVFDO3662UKFW/, /rodent-donors/IGVFDO4725SNCJ/, /rodent-donors/IGVFDO8152XDDC/, /rodent-donors/IGVFDO9340WGNV/, /rodent-donors/IGVFDO6614NNPY/, /rodent-donors/IGVFDO5502NJPS/, /rodent-donors/IGVFDO7957DMLJ/, /rodent-donors/IGVFDO3762EAWT/, /rodent-donors/IGVFDO8958JQIY/, /rodent-donors/IGVFDO5258MBVH/, /rodent-donors/IGVFDO5523UFUN/, /rodent-donors/IGVFDO2292YGGE/, /rodent-donors/IGVFDO2753JGYS/, /rodent-donors/IGVFDO0751WQHI/, /rodent-donors/IGVFDO2645GUSC/, /rodent-donors/IGVFDO6066JIEJ/, /rodent-donors/IGVFDO7255VZBN/, /rodent-donors/IGVFDO9142EUBJ/, /rodent-donors/IGVFDO3534MDFF/, /rodent-donors/IGVFDO2319OUEC/, /rodent-donors/IGVFDO0681EHNP/, /rodent-donors/IGVFDO4788BIQB/, /rodent-donors/IGVFDO4469VYEZ/, /rodent-donors/IGVFDO5177QEWF/, /rodent-donors/IGVFDO0813DZTW/, /rodent-donors/IGVFDO7062NBTQ/, /rodent-donors/IGVFDO0696DMIA/, /rodent-donors/IGVFDO1452VDIT/, /rodent-donors/IGVFDO9374WXKK/, /rodent-donors/IGVFDO2106EEWB/, /rodent-donors/IGVFDO4707SGWM/, /rodent-donors/IGVFDO9202WGJZ/, /rodent-donors/IGVFDO2831PZHE/, /rodent-donors/IGVFDO3640WUBU/, /rodent-donors/IGVFDO7610XXRR/, /rodent-donors/IGVFDO6219LVKW/, /rodent-donors/IGVFDO7254QNQZ/, /rodent-donors/IGVFDO1643VEDI/, /rodent-donors/IGVFDO0624KKTV/, /rodent-donors/IGVFDO3603MEIO/, /rodent-donors/IGVFDO5872DFML/, /rodent-donors/IGVFDO7951JDSP/, /rodent-donors/IGVFDO9199TPBC/, /rodent-donors/IGVFDO5737FRWD/, /rodent-donors/IGVFDO5085MJSP/, /rodent-donors/IGVFDO3655FKMR/, /rodent-donors/IGVFDO1744FDIX/, /rodent-donors/IGVFDO2301HIUQ/, /rodent-donors/IGVFDO0853BCOL/, /rodent-donors/IGVFDO8322VYDU/, /rodent-donors/IGVFDO7007WBAX/, /rodent-donors/IGVFDO9510ILZG/

sparse gene count matrix

intermediate analysis

multiplexed sample: Mus musculus AJ (male, 69 days) epididymis tissue; Mus musculus PWK/PhJ (female, 69 days) oviduct tissue; ... and 190 more samples

Mus musculus multiplexed sample of adrenal gland, epididymis, ovary, oviduct, testis, cellular sub pool(s): 008B_67B

released

Parse SPLiT-seq

ffdd233e-57b8-486c-9bb4-c33b8daf7b06

IGVFDS4399AIVC

GRCh38

/human-donors/IGVFDO5906JTNO/, /human-donors/IGVFDO2586HOGZ/, /human-donors/IGVFDO8538NJBT/, /human-donors/IGVFDO7628YVDD/, /human-donors/IGVFDO8345WLMS/

variants

variants

released

Homo sapiens GRCh38 variants

Homo sapiens

ff53b2d6-8ce6-40ac-b39a-9026efc10103

IGVFDS1331MCPD

in vitro CRISPR screen assay

no certificate

reads

experimental data

Proliferation CRISPR screen

Homo sapiens HUDEP-2 cell line modified with CRISPR cutting SpRY, transduced (lentivirus) with a guide library

released

Proliferation CRISPR cutting screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide

ff4d62e6-1ba9-4010-a061-d74377b15a06

IGVFDS4520GXBK

single-nucleus RNA sequencing assay

false

No limitations

/human-donors/IGVFDO1193ADXF/, /human-donors/IGVFDO0180JQCL/, /human-donors/IGVFDO7387JZDV/, /human-donors/IGVFDO6316TGCK/, /human-donors/IGVFDO7051PRHR/, /human-donors/IGVFDO4191KJBR/, /human-donors/IGVFDO3628ZBBZ/, /human-donors/IGVFDO2031ESZX/, /human-donors/IGVFDO5949WFOO/, /human-donors/IGVFDO2928PSUK/, /human-donors/IGVFDO8891KXRJ/, /human-donors/IGVFDO9462VNBA/

reads

experimental data

10x multiome

multiplexed sample: Homo sapiens (male, 80 years) middle temporal gyrus tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy; Homo sapiens (male, 60 years) putamen tissue associated with Parkinson's disease; ... and 10 more samples

preview

single-nucleus RNA sequencing assay (10x multiome)

ff27c3e6-a2bd-4e96-8eb5-a531fb73dde7

IGVFDS2333QYKL

in vitro CRISPR screen using flow cytometry

no certificate

reads

experimental data

CRISPR FACS screen

Homo sapiens (male) HepG2 cell line (sorting details: Sorted for Top 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)

released

CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide

ff0b6255-6e09-4686-9119-0b6b88ab65d0

IGVFDS1162EVFG

no certificate

8 cube mouse founder strains plate igvf_007 Subpool_2 with Diencephalon/Pituitary as the primary tissue and Gonads as the genetically multiplexed tissue

/rodent-donors/IGVFDO7062NBTQ/, /rodent-donors/IGVFDO5258MBVH/, /rodent-donors/IGVFDO2319OUEC/, /rodent-donors/IGVFDO4469VYEZ/, /rodent-donors/IGVFDO9374WXKK/, /rodent-donors/IGVFDO4725SNCJ/, /rodent-donors/IGVFDO3603MEIO/, /rodent-donors/IGVFDO9510ILZG/, /rodent-donors/IGVFDO6614NNPY/, /rodent-donors/IGVFDO3762EAWT/, /rodent-donors/IGVFDO5523UFUN/, /rodent-donors/IGVFDO3207TERA/, /rodent-donors/IGVFDO0751WQHI/, /rodent-donors/IGVFDO2831PZHE/, /rodent-donors/IGVFDO3662UKFW/, /rodent-donors/IGVFDO9199TPBC/, /rodent-donors/IGVFDO9560CEGZ/, /rodent-donors/IGVFDO2106EEWB/, /rodent-donors/IGVFDO0813DZTW/, /rodent-donors/IGVFDO7957DMLJ/, /rodent-donors/IGVFDO8958JQIY/, /rodent-donors/IGVFDO0681EHNP/, /rodent-donors/IGVFDO4707SGWM/, /rodent-donors/IGVFDO0624KKTV/, /rodent-donors/IGVFDO4788BIQB/, /rodent-donors/IGVFDO5177QEWF/, /rodent-donors/IGVFDO8152XDDC/, /rodent-donors/IGVFDO3436ZMLY/, /rodent-donors/IGVFDO0853BCOL/, /rodent-donors/IGVFDO7254QNQZ/, /rodent-donors/IGVFDO5737FRWD/, /rodent-donors/IGVFDO1452VDIT/, /rodent-donors/IGVFDO7255VZBN/, /rodent-donors/IGVFDO2517TXOT/, /rodent-donors/IGVFDO0026YRCR/, /rodent-donors/IGVFDO8904OIIT/, /rodent-donors/IGVFDO0696DMIA/, /rodent-donors/IGVFDO2301HIUQ/, /rodent-donors/IGVFDO6607QZPA/, /rodent-donors/IGVFDO5539RLXJ/, /rodent-donors/IGVFDO1477BPVO/, /rodent-donors/IGVFDO0430HQIU/, /rodent-donors/IGVFDO1744FDIX/, /rodent-donors/IGVFDO9890MXGN/, /rodent-donors/IGVFDO2292YGGE/, /rodent-donors/IGVFDO1643VEDI/, /rodent-donors/IGVFDO6219LVKW/, /rodent-donors/IGVFDO3655FKMR/, /rodent-donors/IGVFDO3640WUBU/, /rodent-donors/IGVFDO5502NJPS/, /rodent-donors/IGVFDO2645GUSC/, /rodent-donors/IGVFDO8322VYDU/, /rodent-donors/IGVFDO9142EUBJ/, /rodent-donors/IGVFDO7007WBAX/, /rodent-donors/IGVFDO5872DFML/, /rodent-donors/IGVFDO6112GRYR/, /rodent-donors/IGVFDO9340WGNV/, /rodent-donors/IGVFDO5183UZGS/, /rodent-donors/IGVFDO7610XXRR/, /rodent-donors/IGVFDO6141KSSQ/, /rodent-donors/IGVFDO7951JDSP/, /rodent-donors/IGVFDO9202WGJZ/, /rodent-donors/IGVFDO3534MDFF/, /rodent-donors/IGVFDO5085MJSP/, /rodent-donors/IGVFDO6066JIEJ/

sparse gene count matrix

intermediate analysis

multiplexed sample: Mus musculus NOD/ShiLtJ (female, 72 days) pituitary gland tissue; Mus musculus CAST/EiJ (female, 69 days) pituitary gland tissue; ... and 254 more samples

Mus musculus multiplexed sample of epididymis, hypothalamus, ovary, oviduct, pituitary gland, testis, cellular sub pool(s): 007_67A

released

Parse SPLiT-seq

fef7948b-1b97-4b95-810a-93dba11d5beb

IGVFDS3979YUTV

single-nucleus ATAC-seq

false

No limitations

/human-donors/IGVFDO6380POHE/, /human-donors/IGVFDO8584FBOT/, /human-donors/IGVFDO4273OHGB/, /human-donors/IGVFDO1627RQLG/, /human-donors/IGVFDO2028IGVN/, /human-donors/IGVFDO7649CIGW/, /human-donors/IGVFDO8504RBEL/, /human-donors/IGVFDO4783EEYU/, /human-donors/IGVFDO6489DOPG/, /human-donors/IGVFDO1193ADXF/, /human-donors/IGVFDO6837RJUQ/, /human-donors/IGVFDO0698ZMAQ/

reads

experimental data

10x multiome

multiplexed sample: Homo sapiens (female, 82 years) substantia nigra tissue associated with cerebral amyloid angiopathy; Homo sapiens (female, 84 years) cerebellar cortex tissue associated with Parkinson's disease, mild cognitive impairment; ... and 10 more samples

preview

single-nucleus ATAC-seq (10x multiome)

fee07b3b-f2f5-48a6-9b86-4e018b84481b

IGVFDS4191KCRM

single-nucleus RNA sequencing assay

no certificate

/rodent-donors/IGVFDO0624KKTV/, /rodent-donors/IGVFDO1452VDIT/, /rodent-donors/IGVFDO1477BPVO/, /rodent-donors/IGVFDO3662UKFW/, /rodent-donors/IGVFDO2292YGGE/, /rodent-donors/IGVFDO5539RLXJ/, /rodent-donors/IGVFDO0751WQHI/, /rodent-donors/IGVFDO9340WGNV/, /rodent-donors/IGVFDO5810HOHC/, /rodent-donors/IGVFDO6219LVKW/, /rodent-donors/IGVFDO9202WGJZ/, /rodent-donors/IGVFDO3207TERA/, /rodent-donors/IGVFDO9510ILZG/, /rodent-donors/IGVFDO4725SNCJ/, /rodent-donors/IGVFDO5183UZGS/, /rodent-donors/IGVFDO8276XXVT/, /rodent-donors/IGVFDO3762EAWT/, /rodent-donors/IGVFDO5085MJSP/, /rodent-donors/IGVFDO7951JDSP/, /rodent-donors/IGVFDO9199TPBC/, /rodent-donors/IGVFDO5872DFML/, /rodent-donors/IGVFDO3436ZMLY/, /rodent-donors/IGVFDO4788BIQB/, /rodent-donors/IGVFDO7062NBTQ/, /rodent-donors/IGVFDO8698PVAJ/, /rodent-donors/IGVFDO3603MEIO/, /rodent-donors/IGVFDO5737FRWD/, /rodent-donors/IGVFDO2301HIUQ/, /rodent-donors/IGVFDO4469VYEZ/, /rodent-donors/IGVFDO0696DMIA/, /rodent-donors/IGVFDO7254QNQZ/, /rodent-donors/IGVFDO2106EEWB/, /rodent-donors/IGVFDO2831PZHE/, /rodent-donors/IGVFDO5502NJPS/, /rodent-donors/IGVFDO2319OUEC/, /rodent-donors/IGVFDO6141KSSQ/, /rodent-donors/IGVFDO3640WUBU/, /rodent-donors/IGVFDO6124WGNO/, /rodent-donors/IGVFDO6614NNPY/, /rodent-donors/IGVFDO8904OIIT/, /rodent-donors/IGVFDO7255VZBN/, /rodent-donors/IGVFDO0813DZTW/, /rodent-donors/IGVFDO5177QEWF/, /rodent-donors/IGVFDO8152XDDC/, /rodent-donors/IGVFDO9374WXKK/, /rodent-donors/IGVFDO1643VEDI/, /rodent-donors/IGVFDO2517TXOT/, /rodent-donors/IGVFDO0430HQIU/, /rodent-donors/IGVFDO4707SGWM/, /rodent-donors/IGVFDO7957DMLJ/, /rodent-donors/IGVFDO3534MDFF/, /rodent-donors/IGVFDO9890MXGN/, /rodent-donors/IGVFDO8958JQIY/, /rodent-donors/IGVFDO7007WBAX/, /rodent-donors/IGVFDO6112GRYR/, /rodent-donors/IGVFDO7610XXRR/, /rodent-donors/IGVFDO0026YRCR/, /rodent-donors/IGVFDO1744FDIX/, /rodent-donors/IGVFDO5523UFUN/, /rodent-donors/IGVFDO8322VYDU/, /rodent-donors/IGVFDO9560CEGZ/, /rodent-donors/IGVFDO0681EHNP/, /rodent-donors/IGVFDO5258MBVH/, /rodent-donors/IGVFDO0853BCOL/, /rodent-donors/IGVFDO2645GUSC/, /rodent-donors/IGVFDO3655FKMR/, /rodent-donors/IGVFDO4546RHSG/, /rodent-donors/IGVFDO9142EUBJ/, /rodent-donors/IGVFDO6066JIEJ/, /rodent-donors/IGVFDO6607QZPA/

reads, seqspec

experimental data

Parse SPLiT-seq

multiplexed sample: Mus musculus NZO/H1LtJ (female, 69 days) gastrocnemius tissue; Mus musculus NZO/H1LtJ (male, 69 days) left hippocampal formation tissue; ... and 190 more samples

released

Parse SPLiT-seq

fed2a8c8-6cab-48b9-8bba-b93d4f1d75ad

IGVFDS3265EOGA

true

GRU

/human-donors/IGVFDO5261UCLF/, /human-donors/IGVFDO6169GISQ/, /human-donors/IGVFDO7670TOWV/, /human-donors/IGVFDO2718IDDQ/, /human-donors/IGVFDO9716HDYX/, /human-donors/IGVFDO0183MFIP/, /human-donors/IGVFDO6441FSJH/, /human-donors/IGVFDO2965ZTUG/, /human-donors/IGVFDO2492CCQG/, /human-donors/IGVFDO6162MIWK/, /human-donors/IGVFDO8977PNMK/, /human-donors/IGVFDO0657EMJH/, /human-donors/IGVFDO2379DTAU/, /human-donors/IGVFDO6638HIAD/, /human-donors/IGVFDO7140TLQJ/, /human-donors/IGVFDO7650ICPB/, /human-donors/IGVFDO1964RNHE/, /human-donors/IGVFDO5656YCPC/, /human-donors/IGVFDO2620HPCX/, /human-donors/IGVFDO4134ZWBU/, /human-donors/IGVFDO2817PSCX/, /human-donors/IGVFDO4001VEAC/, /human-donors/IGVFDO7813GMND/, /human-donors/IGVFDO8129FWUV/, /human-donors/IGVFDO0720ONIQ/, /human-donors/IGVFDO0324ZSAY/, /human-donors/IGVFDO1038DAII/, /human-donors/IGVFDO1221XJAX/, /human-donors/IGVFDO7725MEWB/, /human-donors/IGVFDO7470LCGC/, /human-donors/IGVFDO8315PGTI/, /human-donors/IGVFDO5614PTYQ/, /human-donors/IGVFDO2650AGWB/, /human-donors/IGVFDO4452ZQSF/, /human-donors/IGVFDO8129UUAA/, /human-donors/IGVFDO8893DMFF/, /human-donors/IGVFDO2750DZPB/, /human-donors/IGVFDO3755LIBB/, /human-donors/IGVFDO9904ZSML/, /human-donors/IGVFDO1364EAZP/, /human-donors/IGVFDO9617JBWJ/, /human-donors/IGVFDO4532PFAJ/, /human-donors/IGVFDO4876ENMD/, /human-donors/IGVFDO5729MXSO/

reads, seqspec

lipid-conjugated oligo sequencing

/measurement-sets/IGVFDS9875NBZW/, /measurement-sets/IGVFDS1125HXCL/

multiplexed sample: Homo sapiens (mixed sex) induced pluripotent stem differentiated cell specimen induced to islet of Langerhans for 11 days; Homo sapiens (mixed sex) induced pluripotent stem differentiated cell specimen induced to islet of Langerhans for 3 days; ... and 6 more samples

released

lipid-conjugated oligo sequencing for single-nucleus ATAC-seq (10x multiome with MULTI-seq), single-nucleus RNA sequencing assay (10x multiome with MULTI-seq)

fecb8d55-6ae5-4066-9983-07613d9e62f3

IGVFDS3032KHHX

single-cell ATAC-seq

no certificate

reads, seqspec

experimental data

SHARE-seq

Mus musculus C57BL/6 (female) brain tissue (cellular sub pool: SS-PKR 130)

released

single-cell ATAC-seq (SHARE-seq)

fec43dfa-d933-4eac-b4cc-2f0a8b5c604d

IGVFDS2755YZNI

in vitro CRISPR screen using flow cytometry

no certificate

reads

experimental data

Variant-EFFECTS

Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library

preview

CRISPR prime editing Variant-EFFECTS sorted on the expression of PPIF integrating a guide (sgRNA) library targeting sequence variants in a genomic locus

feb8e35f-3b97-49f7-b3c5-225c936360b6

IGVFDS6647HVMC

in vitro CRISPR screen using flow cytometry

no certificate

reads

experimental data

Variant-EFFECTS

Homo sapiens (male) Jurkat cell line (sorting details: FACS bin for 11-20% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library

released

CRISPR prime editing Variant-EFFECTS sorted on the expression of PPIF integrating a guide (sgRNA) library targeting sequence variants in a genomic locus

feb7d08a-1287-4cac-b362-f81fd5ba1f81

IGVFDS7903FOXV

false

No limitations

/human-donors/IGVFDO1756PPKO/, /human-donors/IGVFDO7411YYYE/

index, cell hashing barcodes, fragments, peaks, raw feature barcode matrix

intermediate analysis

/institutional-certificates/e5598331-9e7c-4bd5-8e7b-64d5a4529006/, /institutional-certificates/f37dfa73-f4f1-4bfe-a312-9eade62d5988/

multiplexed sample: Homo sapiens (female) H7-hESC differentiated cell specimen; Homo sapiens (male) GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 6 days; ... and 10 more samples

Homo sapiens multiplexed sample of GM25256 (WTC-11), H7-hESC

released

single-nucleus ATAC-seq (10x multiome with MULTI-seq), single-nucleus RNA sequencing assay (10x multiome with MULTI-seq)

feb0379c-6f89-409c-8579-b32a0aa29fb3

IGVFDS3949LHHW

single-nucleus ATAC-seq

false

No limitations

/human-donors/IGVFDO7227BIXW/, /human-donors/IGVFDO9236YUAT/, /human-donors/IGVFDO7186XJLL/, /human-donors/IGVFDO5205IAEO/, /human-donors/IGVFDO6000JDZW/, /human-donors/IGVFDO0967LMSM/, /human-donors/IGVFDO2559GIIZ/, /human-donors/IGVFDO4825ZGIS/, /human-donors/IGVFDO6380POHE/, /human-donors/IGVFDO7387JZDV/

reads

experimental data

10x multiome

multiplexed sample: Homo sapiens (male, 79 years) posterior cingulate gyrus tissue; Homo sapiens (male, 80 years) posterior cingulate gyrus tissue associated with Parkinson's disease, cerebral amyloid angiopathy, mild cognitive impairment; ... and 8 more samples

preview

single-nucleus ATAC-seq (10x multiome)

fe8a3ce7-9528-42c7-a190-0a2890bb9ad8

IGVFDS2606PSFA

in vitro CRISPR screen using flow cytometry

no certificate

reads

experimental data

CRISPR FlowFISH screen

Homo sapiens (female) TeloHAEC cell line (sorting details: FACS 60-80% expression of NFKBIA) modified with CRISPRi Sp-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library

released

CRISPR interference FlowFISH screen sorted on the expression of NFKBIA integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide associated with blood pressure

fe84d7f5-150b-45a5-aaed-9810416aa2e7

IGVFDS4363PDBQ

in vitro CRISPR screen using flow cytometry

no certificate

reads

experimental data

Variant-EFFECTS

Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library

released

CRISPR prime editing Variant-EFFECTS sorted on the expression of PPIF integrating a guide (sgRNA) library targeting sequence variants in a genomic locus

fe739718-a398-4e5c-b7b5-4d95497c90ad

IGVFDS2419JZMR

in vitro CRISPR screen using flow cytometry

no certificate

reads

experimental data

CRISPR FlowFISH screen

Homo sapiens (female) TeloHAEC cell line (sorting details: FACS bin for 76-100% expression of TLNRD1) modified with CRISPRi Sp-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library

released

CRISPR interference FlowFISH screen sorted on the expression of TLNRD1 integrating a guide (sgRNA) library targeting candidate cis-regulatory elements in a genomic locus

fe738818-a459-4367-8223-af72aa6bca96

IGVFDS4736IKQS

in vitro CRISPR screen using flow cytometry

no certificate

reads

experimental data

Variant-EFFECTS

Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library

released

unsorted FACS input CRISPR prime editing Variant-EFFECTS integrating a guide (sgRNA) library targeting sequence variants in a genomic locus

fe6d143f-dbd2-40a5-b72b-55021f81951f

IGVFDS8153TZWE

single-cell RNA sequencing assay

true

GRU-PUB

seqspec, reads

experimental data

mtscMultiome

Homo sapiens (male, 29 years) peripheral blood mononuclear cell

preview

mtscMultiome

fe691699-aab9-4f5b-9441-94f41f4020b1

IGVFDS2414ATDI

single-nucleus ATAC-seq

false

No limitations

/human-donors/IGVFDO7606UOXI/, /human-donors/IGVFDO7720JNYZ/, /human-donors/IGVFDO6837RJUQ/, /human-donors/IGVFDO9028PIDF/, /human-donors/IGVFDO1052TZWO/, /human-donors/IGVFDO3500WGWY/, /human-donors/IGVFDO6513APBX/, /human-donors/IGVFDO0411QFOF/, /human-donors/IGVFDO4191KJBR/, /human-donors/IGVFDO0966KXTA/, /human-donors/IGVFDO0773NPOH/, /human-donors/IGVFDO0967LMSM/

reads

experimental data

10x multiome

multiplexed sample: Homo sapiens (male, 87 years) cerebellar cortex tissue associated with Parkinson's disease, cerebral amyloid angiopathy; Homo sapiens (male, 72 years) middle temporal gyrus tissue associated with Parkinson's disease; ... and 10 more samples

preview

single-nucleus ATAC-seq (10x multiome)

fe41d4f3-932f-4b0b-9a24-c80507121a08

IGVFDS9167HYTZ

true

HMB

filtered feature barcode matrix

intermediate analysis

multiplexed sample: Homo sapiens (male) B differentiated cell specimen induced to plasmablast for 2 days; Homo sapiens (male) B differentiated cell specimen induced to plasmablast for 6 days; ... and 2 more samples

Homo sapiens multiplexed sample of B cell

released

scRNA-seq

fe3918c4-fadf-4e29-9efc-ee9957c49ab2

IGVFDS3969UCCQ

bulk RNA-seq assay

false

No limitations

reads

experimental data

RNA-seq

Homo sapiens CD8-positive, alpha-beta memory T cell modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4)

released

CRISPR knockout RNA-seq integrating a guide (sgRNA) library targeting transcription start sites in GATA3

fe29fcd6-36dd-4bba-acde-cc30fbb5ebc7