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175 items
10x multiome with MULTI-seq
GRCh38
index, cell hashing barcodes, fragments, peaks, raw feature barcode matrix
tbi, tsv, bed, hdf5
intermediate analysis
multiplexed sample: H7-hESC differentiated cell specimen, female, Homo sapiens; GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 6 days, male, Homo sapiens; ... and 10 more samples
10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
intermediate analysis
Unspecified assay
lentiMPRA
reporter genomic variant effects
tsv
principal analysis
neural progenitor pooled cell specimen, Homo sapiens transduced (lentivirus) with a reporter library
lentiMPRA: reporter genomic variant effects
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens treated with 1 μM Endothelin-1 for 3 days, transfected with a guide library
HiCAR: contact matrix
ATAC-seq
GRCh38
fold change over control, peak quantifications, alignments
tsv, bam
principal analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens transduced (lentivirus) with a expression vector library
ATAC-seq: alignments, fold change over control, peak quantifications
Perturb-seq
sparse gene count matrix, filtered feature barcode matrix, raw feature barcode matrix
h5ad, hdf5, pkl
principal analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW265), male, Homo sapiens modified with CRISPRi Sp-dCas9, 3 week(s) after transfection with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW262), male, Homo sapiens modified with CRISPRi Sp-dCas9, 3 week(s) after transfection with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW266), male, Homo sapiens modified with CRISPRi Sp-dCas9, 3 week(s) after transfection with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW261), male, Homo sapiens modified with CRISPRi Sp-dCas9, 3 week(s) after transfection with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW264), male, Homo sapiens modified with CRISPRi Sp-dCas9, 3 week(s) after transfection with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW267), male, Homo sapiens modified with CRISPRi Sp-dCas9, 3 week(s) after transfection with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW263), male, Homo sapiens modified with CRISPRi Sp-dCas9, 3 week(s) after transfection with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW268), male, Homo sapiens modified with CRISPRi Sp-dCas9, 3 week(s) after transfection with a guide library
interference Perturb-seq: filtered feature barcode matrix, raw feature barcode matrix, sparse gene count matrix
Perturb-seq
sparse gene count matrix, filtered feature barcode matrix, raw feature barcode matrix, unfiltered local differential expression, unfiltered global differential expression
h5ad, hdf5, pkl, csv
principal analysis
H9 differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW421), female, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, H9 differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW422), female, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, H9 differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW423), female, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, H9 differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW424), female, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library
interference Perturb-seq: filtered feature barcode matrix, raw feature barcode matrix, sparse gene count matrix, unfiltered global differential expression, unfiltered local differential expression
CRISPR FlowFISH screen, Proliferation CRISPR screen
guide quantifications
csv
principal analysis
TeloHAEC cell line, female, Homo sapiens modified with CRISPRi Sp-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library
CRISPR interference FlowFISH screen, Proliferation CRISPR interference screen: guide quantifications
10x multiome with MULTI-seq
GRCh38
peaks, index, raw feature barcode matrix, fragments, cell hashing barcodes
bed, tbi, hdf5, tsv
intermediate analysis
multiplexed sample: H9 differentiated cell specimen induced to neuron for 6 days, female, Homo sapiens; H9 differentiated cell specimen induced to neuron for 6 days, female, Homo sapiens; ... and 6 more samples
10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
CRISPR FACS screen
custom
guide quantifications, fold change over control, alignments
csv, tsv, bam
principal analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 0-10% expression of CCR7) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4), CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 90-100% expression of CCR7) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4)
CRISPR activation FACS screen targeting CCR7: alignments, fold change over control, guide quantifications
10x multiome with MULTI-seq
GRCh38
fragments, raw feature barcode matrix, cell hashing barcodes, peaks, index
tsv, hdf5, bed, tbi
intermediate analysis
multiplexed sample: H1-hESC differentiated cell specimen induced to islet of Langerhans for 18 days, male, Homo sapiens; H1-hESC differentiated cell specimen induced to islet of Langerhans for 7 days, male, Homo sapiens; ... and 6 more samples
10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens treated with 1 μM Endothelin-1 for 3 days, transfected with a guide library
HiCAR: contact matrix
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library
HiCAR: contact matrix
10x multiome with MULTI-seq
GRCh38
cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
tsv, tbi, bed, hdf5
intermediate analysis
multiplexed sample: GM25256 (WTC-11) differentiated cell specimen induced to liver for 18 days, male, Homo sapiens; GM25256 (WTC-11) differentiated cell specimen induced to liver for 13 days, male, Homo sapiens; ... and 10 more samples
10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
10x multiome with MULTI-seq
GRCh38
peaks, index, fragments, cell hashing barcodes, raw feature barcode matrix
bed, tbi, tsv, hdf5
intermediate analysis
multiplexed sample: H9 differentiated cell specimen induced to cardiac muscle cell for 15 days, female, Homo sapiens; HepG2 cell line, male, Homo sapiens grown in DMEM without serum; ... and 10 more samples
10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
HiCAR
contact matrix
mcool, cool
intermediate analysis
HL-1 cell line, female, Mus musculus C57BL/6J transfected with a guide library
HiCAR: contact matrix
intermediate analysis
Unspecified assay
10x multiome with MULTI-seq
GRCh38
peaks, fragments, index, raw feature barcode matrix, cell hashing barcodes
bed, tsv, tbi, hdf5
intermediate analysis
multiplexed sample: B differentiated cell specimen induced to plasmablast for 6 days, female, Homo sapiens; B differentiated cell specimen induced to plasmablast for 5 days, female, Homo sapiens; ... and 10 more samples
10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
Variant-EFFECTS
variant effects
tsv
principal analysis
THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 35-45% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 80-90% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 55-65% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 90-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 0-10% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 11-20% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)
prime editing Variant-EFFECTS targeting PPIF: variant effects
ATAC-seq
GRCh38
fold change over control, peak quantifications, alignments
tsv, bam
principal analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens transduced (lentivirus) with a expression vector library
ATAC-seq: alignments, fold change over control, peak quantifications
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library
HiCAR: contact matrix
Perturb-seq
sparse gene count matrix, filtered feature barcode matrix, raw feature barcode matrix, unfiltered local differential expression, unfiltered global differential expression
h5ad, hdf5, pkl, csv
principal analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW263), male, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW268), male, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW265), male, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW266), male, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW267), male, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW261), male, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW262), male, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW264), male, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library
interference Perturb-seq: filtered feature barcode matrix, raw feature barcode matrix, sparse gene count matrix, unfiltered global differential expression, unfiltered local differential expression
RNA-seq
GRCh38
transcript quantifications, fold change over control, transcriptome alignments
tsv, csv, bam
principal analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 28 days, male, Homo sapiens, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 28 days, male, Homo sapiens treated with 4 μM GSK3 inhibition for 7 days
RNA-seq: fold change over control, transcript quantifications, transcriptome alignments
intermediate analysis
Unspecified assay
10x multiome with MULTI-seq
GRCh38
peaks, index, fragments, cell hashing barcodes, raw feature barcode matrix
bed, tbi, tsv, hdf5
intermediate analysis
multiplexed sample: B differentiated cell specimen induced to plasmablast for 1 day, male, Homo sapiens; B differentiated cell specimen induced to plasmablast for 5 days, male, Homo sapiens; ... and 5 more samples
10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix