IGVFFI9048CVLI

released
validated
{
    "@context": "/terms/",
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    "accession": "IGVFFI9048CVLI",
    "aliases": [
        "jay-shendure:tabularfile_S7_Chardon-McDiarmid"
    ],
    "analysis_step_version": "/analysis-step-versions/b4bb30ef-db5c-4314-bc56-a9f536851ec2/",
    "assay_titles": [
        "scCRISPR screen"
    ],
    "audit": {
        "INTERNAL_ACTION": [
            {
                "category": "mismatched status",
                "detail": "Released tabular file [IGVFFI9048CVLI](/tabular-files/IGVFFI9048CVLI/) has in progress subobject analysis step version [b4bb30ef-db5c-4314-bc56-a9f536851ec2](/analysis-step-versions/b4bb30ef-db5c-4314-bc56-a9f536851ec2/).",
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                "path": "/tabular-files/IGVFFI9048CVLI/"
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    },
    "award": {
        "@id": "/awards/HG011966/",
        "component": "functional characterization"
    },
    "barcode_map_for": [],
    "content_md5sum": "f85b21f1e51476611592ee1d2e50e5f3",
    "content_type": "differential gene expression quantifications",
    "controlled_access": false,
    "creation_timestamp": "2024-10-14T18:39:01.617294+00:00",
    "derived_from": [
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        "/sequence-files/IGVFFI7687RJYL/",
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        "/sequence-files/IGVFFI7407CDAT/",
        "/sequence-files/IGVFFI4517FSHP/",
        "/sequence-files/IGVFFI2611VQUT/",
        "/sequence-files/IGVFFI2702LBCH/",
        "/sequence-files/IGVFFI8009AYNA/",
        "/sequence-files/IGVFFI6618WYLI/",
        "/sequence-files/IGVFFI0113PKVX/",
        "/sequence-files/IGVFFI7653WTAT/",
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    "description": "iPSC-derived neuron hits (EFDR < 0.1). P-values are from a two-tailed Wilcoxon ranksum test.",
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    "file_set": {
        "@id": "/analysis-sets/IGVFDS4021XJLW/",
        "accession": "IGVFDS4021XJLW",
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                "@id": "/in-vitro-systems/IGVFSM8317ZTFV/",
                "accession": "IGVFSM8317ZTFV",
                "classifications": [
                    "differentiated cell specimen"
                ],
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                    {
                        "@id": "/crispr-modifications/426a4099-35d9-4c65-8851-5e788a3d4e70/",
                        "modality": "activation",
                        "status": "released",
                        "summary": "CRISPRa Sp-dCas9-VPH"
                    }
                ],
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                        "@id": "/sample-terms/EFO_0009747/",
                        "status": "released",
                        "term_name": "GM25256 (WTC-11)"
                    }
                ],
                "status": "released",
                "summary": "GM25256 (WTC-11) differentiated cell specimen induced to neuron for 19 days (cellular sub pool: 10Xlane3), male, Homo sapiens modified with CRISPRa Sp-dCas9-VPH, transfected with a guide library",
                "targeted_sample_term": {
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                    "status": "released",
                    "term_name": "neuron"
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            },
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                "@id": "/in-vitro-systems/IGVFSM8382KOXO/",
                "accession": "IGVFSM8382KOXO",
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                        "@id": "/crispr-modifications/426a4099-35d9-4c65-8851-5e788a3d4e70/",
                        "modality": "activation",
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                        "summary": "CRISPRa Sp-dCas9-VPH"
                    }
                ],
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                        "@id": "/sample-terms/EFO_0009747/",
                        "status": "released",
                        "term_name": "GM25256 (WTC-11)"
                    }
                ],
                "status": "released",
                "summary": "GM25256 (WTC-11) differentiated cell specimen induced to neuron for 19 days (cellular sub pool: 10Xlane4), male, Homo sapiens modified with CRISPRa Sp-dCas9-VPH, transfected with a guide library",
                "targeted_sample_term": {
                    "@id": "/sample-terms/CL_0000540/",
                    "status": "released",
                    "term_name": "neuron"
                },
                "taxa": "Homo sapiens"
            },
            {
                "@id": "/in-vitro-systems/IGVFSM7750SNNY/",
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                "classifications": [
                    "differentiated cell specimen"
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                        "@id": "/crispr-modifications/426a4099-35d9-4c65-8851-5e788a3d4e70/",
                        "modality": "activation",
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                        "summary": "CRISPRa Sp-dCas9-VPH"
                    }
                ],
                "sample_terms": [
                    {
                        "@id": "/sample-terms/EFO_0009747/",
                        "status": "released",
                        "term_name": "GM25256 (WTC-11)"
                    }
                ],
                "status": "released",
                "summary": "GM25256 (WTC-11) differentiated cell specimen induced to neuron for 19 days (cellular sub pool: 10Xlane1), male, Homo sapiens modified with CRISPRa Sp-dCas9-VPH, transfected with a guide library",
                "targeted_sample_term": {
                    "@id": "/sample-terms/CL_0000540/",
                    "status": "released",
                    "term_name": "neuron"
                },
                "taxa": "Homo sapiens"
            },
            {
                "@id": "/in-vitro-systems/IGVFSM9913PXTT/",
                "accession": "IGVFSM9913PXTT",
                "classifications": [
                    "differentiated cell specimen"
                ],
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                    {
                        "@id": "/crispr-modifications/426a4099-35d9-4c65-8851-5e788a3d4e70/",
                        "modality": "activation",
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                        "summary": "CRISPRa Sp-dCas9-VPH"
                    }
                ],
                "sample_terms": [
                    {
                        "@id": "/sample-terms/EFO_0009747/",
                        "status": "released",
                        "term_name": "GM25256 (WTC-11)"
                    }
                ],
                "status": "released",
                "summary": "GM25256 (WTC-11) differentiated cell specimen induced to neuron for 19 days (cellular sub pool: 10Xlane2), male, Homo sapiens modified with CRISPRa Sp-dCas9-VPH, transfected with a guide library",
                "targeted_sample_term": {
                    "@id": "/sample-terms/CL_0000540/",
                    "status": "released",
                    "term_name": "neuron"
                },
                "taxa": "Homo sapiens"
            }
        ],
        "status": "released",
        "summary": "scCRISPR activation screen: differential gene expression quantifications, sparse gene count matrix"
    },
    "file_size": 2012,
    "gene_list_for": [],
    "href": "/tabular-files/IGVFFI9048CVLI/@@download/IGVFFI9048CVLI.csv.gz",
    "input_file_for": [],
    "integrated_in": [],
    "lab": {
        "@id": "/labs/jay-shendure/",
        "title": "Jay Shendure, UW"
    },
    "loci_list_for": [],
    "md5sum": "8bfc3143c0f36a6b32ae92bbee32a928",
    "release_timestamp": "2025-01-22T05:57:11.844127+00:00",
    "s3_uri": "s3://igvf-files/2024/10/14/8d65544d-405c-4fa3-91f8-2fcaa3be20e1/IGVFFI9048CVLI.csv.gz",
    "schema_version": "13",
    "status": "released",
    "submitted_by": {
        "@id": "/users/73f58e9f-8f5d-4fee-a7cd-dd63c0167e4b/",
        "title": "Beth Martin"
    },
    "submitted_file_name": "/net/shendure/vol1/home/martin91/IGVF/forupload/CRISPRa/41467_2024_52490_MOESM10_ESM.csv.gz",
    "summary": "differential gene expression quantifications",
    "upload_status": "validated",
    "uuid": "8d65544d-405c-4fa3-91f8-2fcaa3be20e1",
    "workflow": {
        "@id": "/workflows/IGVFWF1905PJEA/",
        "name": "Shendure scCRISPRa Pipeline",
        "uniform_pipeline": false
    }
}