IGVFFI4612KEHH

released
validated
{
    "@context": "/terms/",
    "@id": "/tabular-files/IGVFFI4612KEHH/",
    "@type": [
        "TabularFile",
        "File",
        "Item"
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    "accession": "IGVFFI4612KEHH",
    "aliases": [
        "jay-shendure:tabularfile_S11_Chardon-McDiarmid"
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    "analysis_step_version": "/analysis-step-versions/c3d281e0-f647-4d3c-8ed5-710329d183f2/",
    "assay_titles": [
        "scCRISPR screen"
    ],
    "audit": {
        "INTERNAL_ACTION": [
            {
                "category": "mismatched status",
                "detail": "Released tabular file [IGVFFI4612KEHH](/tabular-files/IGVFFI4612KEHH/) has in progress subobject analysis step version [c3d281e0-f647-4d3c-8ed5-710329d183f2](/analysis-step-versions/c3d281e0-f647-4d3c-8ed5-710329d183f2/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/tabular-files/IGVFFI4612KEHH/"
            }
        ]
    },
    "award": {
        "@id": "/awards/HG011966/",
        "component": "functional characterization"
    },
    "barcode_map_for": [],
    "content_md5sum": "d93232ee21881de57042d5c6693f0fc0",
    "content_type": "differential gene expression quantifications",
    "controlled_access": false,
    "creation_timestamp": "2024-10-14T18:39:03.562166+00:00",
    "derived_from": [
        "/sequence-files/IGVFFI3189OKPU/",
        "/sequence-files/IGVFFI9764UXRA/",
        "/sequence-files/IGVFFI4648IIPG/",
        "/sequence-files/IGVFFI7570AUYM/",
        "/sequence-files/IGVFFI3927QEMS/",
        "/sequence-files/IGVFFI1733REWQ/",
        "/sequence-files/IGVFFI5295OHTL/",
        "/sequence-files/IGVFFI3658HZBE/",
        "/sequence-files/IGVFFI6893EPCL/",
        "/sequence-files/IGVFFI0355AKWQ/",
        "/sequence-files/IGVFFI0332PBFZ/",
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    ],
    "description": "SCEPTRE K562 hits (FDR < 0.1). Two-tailed SCEPTRE P-values were derived using default parameters. SCEPTRE P-values were then Benjamini-Hochberg corrected and those < 0.1 were kept for two-sided discovery sets.",
    "file_format": "csv",
    "file_format_specifications": [
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    "file_set": {
        "@id": "/analysis-sets/IGVFDS9078ZWQH/",
        "accession": "IGVFDS9078ZWQH",
        "file_set_type": "principal analysis",
        "samples": [
            {
                "@id": "/in-vitro-systems/IGVFSM9542NUGS/",
                "accession": "IGVFSM9542NUGS",
                "classifications": [
                    "cell line"
                ],
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                        "@id": "/crispr-modifications/8b61bce4-105c-435e-9b32-1c8903566a9b/",
                        "modality": "activation",
                        "status": "released",
                        "summary": "CRISPRa Sp-dCas9-VP64-p65-Rta (VPR)"
                    }
                ],
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                    {
                        "@id": "/sample-terms/EFO_0002067/",
                        "status": "released",
                        "term_name": "K562"
                    }
                ],
                "status": "released",
                "summary": "K562 cell line (cellular sub pool: 10Xlane2), female, Homo sapiens modified with CRISPRa Sp-dCas9-VP64-p65-Rta (VPR), transfected with a guide library",
                "taxa": "Homo sapiens"
            },
            {
                "@id": "/in-vitro-systems/IGVFSM9390JSDH/",
                "accession": "IGVFSM9390JSDH",
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                        "@id": "/crispr-modifications/ee99bf66-2a5a-4ec6-8380-9434b259afd1/",
                        "modality": "activation",
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                        "summary": "CRISPRa Sp-dCas9-VP64"
                    }
                ],
                "sample_terms": [
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                        "@id": "/sample-terms/EFO_0002067/",
                        "status": "released",
                        "term_name": "K562"
                    }
                ],
                "status": "released",
                "summary": "K562 cell line (cellular sub pool: 10Xlane2), female, Homo sapiens modified with CRISPRa Sp-dCas9-VP64, transfected with a guide library",
                "taxa": "Homo sapiens"
            },
            {
                "@id": "/in-vitro-systems/IGVFSM1594ZOQH/",
                "accession": "IGVFSM1594ZOQH",
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                        "modality": "activation",
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                        "summary": "CRISPRa Sp-dCas9-VP64-p65-Rta (VPR)"
                    }
                ],
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                        "@id": "/sample-terms/EFO_0002067/",
                        "status": "released",
                        "term_name": "K562"
                    }
                ],
                "status": "released",
                "summary": "K562 cell line (cellular sub pool: 10Xlane1), female, Homo sapiens modified with CRISPRa Sp-dCas9-VP64-p65-Rta (VPR), transfected with a guide library",
                "taxa": "Homo sapiens"
            },
            {
                "@id": "/in-vitro-systems/IGVFSM4521QSSO/",
                "accession": "IGVFSM4521QSSO",
                "classifications": [
                    "cell line"
                ],
                "modifications": [
                    {
                        "@id": "/crispr-modifications/ee99bf66-2a5a-4ec6-8380-9434b259afd1/",
                        "modality": "activation",
                        "status": "released",
                        "summary": "CRISPRa Sp-dCas9-VP64"
                    }
                ],
                "sample_terms": [
                    {
                        "@id": "/sample-terms/EFO_0002067/",
                        "status": "released",
                        "term_name": "K562"
                    }
                ],
                "status": "released",
                "summary": "K562 cell line (cellular sub pool: 10Xlane1), female, Homo sapiens modified with CRISPRa Sp-dCas9-VP64, transfected with a guide library",
                "taxa": "Homo sapiens"
            }
        ],
        "status": "released",
        "summary": "scCRISPR activation screen: differential gene expression quantifications, sparse gene count matrix"
    },
    "file_size": 3314,
    "gene_list_for": [],
    "href": "/tabular-files/IGVFFI4612KEHH/@@download/IGVFFI4612KEHH.csv.gz",
    "input_file_for": [],
    "integrated_in": [],
    "lab": {
        "@id": "/labs/jay-shendure/",
        "title": "Jay Shendure, UW"
    },
    "loci_list_for": [],
    "md5sum": "013881a7815d1cd88a554fb89991733f",
    "release_timestamp": "2025-01-22T05:57:50.602710+00:00",
    "s3_uri": "s3://igvf-files/2024/10/14/12aa9f23-4832-4e9e-9cc2-9d94f4545063/IGVFFI4612KEHH.csv.gz",
    "schema_version": "13",
    "status": "released",
    "submitted_by": {
        "@id": "/users/73f58e9f-8f5d-4fee-a7cd-dd63c0167e4b/",
        "title": "Beth Martin"
    },
    "submitted_file_name": "/net/shendure/vol1/home/martin91/IGVF/forupload/CRISPRa/41467_2024_52490_MOESM14_ESM.csv.gz",
    "summary": "differential gene expression quantifications",
    "upload_status": "validated",
    "uuid": "12aa9f23-4832-4e9e-9cc2-9d94f4545063"
}