{
"@context": "/terms/",
"@id": "/tabular-files/IGVFFI4434LXUU/",
"@type": [
"TabularFile",
"File",
"Item"
],
"accession": "IGVFFI4434LXUU",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_CAAC-THP1_Variant-EFFECTS_variant_effects_file"
],
"analysis_step_version": "/analysis-step-versions/b1581dec-2980-4a2e-8884-4e95219da4d4/",
"assay_titles": [
"Variant-EFFECTS"
],
"assembly": "hg19",
"audit": {},
"award": {
"@id": "/awards/HG011972/",
"component": "functional characterization"
},
"barcode_map_for": [],
"checkfiles_version": "v20",
"content_md5sum": "5b59a60422930f400aa3c05cec0582e2",
"content_type": "variant effects",
"controlled_access": false,
"creation_timestamp": "2024-12-17T21:03:46.141424+00:00",
"derived_from": [
"/sequence-files/IGVFFI4386MPXS/",
"/sequence-files/IGVFFI0167YGVX/",
"/sequence-files/IGVFFI7916EOVD/",
"/sequence-files/IGVFFI7291WBMH/",
"/sequence-files/IGVFFI1764MCYJ/",
"/sequence-files/IGVFFI1276APXV/",
"/sequence-files/IGVFFI4550FNKT/",
"/sequence-files/IGVFFI7616EAFV/",
"/sequence-files/IGVFFI1765FXIA/",
"/sequence-files/IGVFFI1505LROH/",
"/sequence-files/IGVFFI3109FSCI/",
"/sequence-files/IGVFFI8118RYZI/",
"/sequence-files/IGVFFI1020CIMY/",
"/sequence-files/IGVFFI8042BYQK/",
"/sequence-files/IGVFFI4716MCYJ/",
"/sequence-files/IGVFFI2907FCZP/",
"/sequence-files/IGVFFI7856CVGD/",
"/sequence-files/IGVFFI2364MYCD/",
"/sequence-files/IGVFFI1009QSPW/",
"/sequence-files/IGVFFI6125LNYA/",
"/sequence-files/IGVFFI1073ATRZ/",
"/sequence-files/IGVFFI0219BOCG/",
"/sequence-files/IGVFFI0839MJWJ/",
"/sequence-files/IGVFFI4770UACM/",
"/sequence-files/IGVFFI8998DDEP/",
"/sequence-files/IGVFFI5157FAXJ/",
"/sequence-files/IGVFFI2718FXYV/",
"/sequence-files/IGVFFI2519HVPH/",
"/sequence-files/IGVFFI2654IOWE/",
"/sequence-files/IGVFFI1249BVFR/",
"/sequence-files/IGVFFI0572QQWS/",
"/sequence-files/IGVFFI3269PGEH/",
"/sequence-files/IGVFFI7458HBHT/",
"/sequence-files/IGVFFI6216NNVG/",
"/sequence-files/IGVFFI2739UJXX/",
"/sequence-files/IGVFFI7333YZKV/",
"/sequence-files/IGVFFI3289ISSS/",
"/sequence-files/IGVFFI7760XBLD/",
"/sequence-files/IGVFFI2847LPVS/",
"/sequence-files/IGVFFI0455CFQK/",
"/sequence-files/IGVFFI9758LNMC/",
"/sequence-files/IGVFFI5349NDCJ/",
"/sequence-files/IGVFFI6503DVXT/",
"/sequence-files/IGVFFI0208SJFM/",
"/sequence-files/IGVFFI5841RNBF/",
"/sequence-files/IGVFFI9150CLVB/",
"/sequence-files/IGVFFI9532DFHK/",
"/sequence-files/IGVFFI4397ADGZ/",
"/sequence-files/IGVFFI8472ZRTH/",
"/sequence-files/IGVFFI5036LWWU/",
"/sequence-files/IGVFFI0238OVHA/",
"/sequence-files/IGVFFI6156FVZX/",
"/sequence-files/IGVFFI2120SRRR/",
"/sequence-files/IGVFFI1980PXUO/",
"/sequence-files/IGVFFI8020VCUY/",
"/sequence-files/IGVFFI1405SUWK/",
"/sequence-files/IGVFFI4033OVLA/",
"/sequence-files/IGVFFI9739MMIU/",
"/sequence-files/IGVFFI3229MNJP/",
"/sequence-files/IGVFFI3547UHDU/",
"/sequence-files/IGVFFI9601YPAU/",
"/sequence-files/IGVFFI4789ELUN/",
"/sequence-files/IGVFFI7267CIMW/",
"/sequence-files/IGVFFI7423TDGE/",
"/sequence-files/IGVFFI9246HOEG/",
"/sequence-files/IGVFFI4310VYKE/",
"/sequence-files/IGVFFI7314ENTY/",
"/sequence-files/IGVFFI3291LAEI/",
"/sequence-files/IGVFFI4849QXVX/",
"/sequence-files/IGVFFI3639PAVD/",
"/sequence-files/IGVFFI4093JJAC/",
"/sequence-files/IGVFFI6911EALG/",
"/sequence-files/IGVFFI1072IWQO/",
"/sequence-files/IGVFFI2310BGXN/",
"/sequence-files/IGVFFI4337SADE/",
"/sequence-files/IGVFFI2649OYLU/",
"/sequence-files/IGVFFI9058JPJY/",
"/sequence-files/IGVFFI7191XYGW/",
"/sequence-files/IGVFFI7069KREC/",
"/sequence-files/IGVFFI4264DSTB/",
"/sequence-files/IGVFFI9029YWST/",
"/sequence-files/IGVFFI1620BNXO/",
"/sequence-files/IGVFFI2571GXGO/",
"/sequence-files/IGVFFI6944AWEY/",
"/sequence-files/IGVFFI9801DKDE/",
"/sequence-files/IGVFFI1317VBVJ/",
"/sequence-files/IGVFFI7792IXTX/",
"/sequence-files/IGVFFI1299KAPD/",
"/sequence-files/IGVFFI1450FBZT/",
"/sequence-files/IGVFFI3326ARRC/",
"/sequence-files/IGVFFI4233TZPC/",
"/sequence-files/IGVFFI2997QEGG/",
"/sequence-files/IGVFFI5773KQAM/",
"/sequence-files/IGVFFI1312RPXY/",
"/sequence-files/IGVFFI6538IDXC/",
"/sequence-files/IGVFFI3914XBNC/",
"/sequence-files/IGVFFI9132PGMZ/",
"/sequence-files/IGVFFI3771EXDX/",
"/sequence-files/IGVFFI7059LNIA/",
"/sequence-files/IGVFFI5517MYIN/",
"/sequence-files/IGVFFI0075NUXD/",
"/sequence-files/IGVFFI8950FMFU/",
"/sequence-files/IGVFFI2537GOGQ/",
"/sequence-files/IGVFFI3359CJNQ/",
"/sequence-files/IGVFFI5406BHHO/",
"/sequence-files/IGVFFI5710XKDQ/",
"/sequence-files/IGVFFI7618DMWF/",
"/sequence-files/IGVFFI4306LDVB/",
"/sequence-files/IGVFFI1657YMEW/",
"/sequence-files/IGVFFI7969GKEQ/",
"/sequence-files/IGVFFI9427EJWH/",
"/sequence-files/IGVFFI9363WKYX/",
"/sequence-files/IGVFFI4474PIHT/",
"/sequence-files/IGVFFI1461XFOL/",
"/sequence-files/IGVFFI3559IDDT/",
"/sequence-files/IGVFFI2931QPFJ/",
"/sequence-files/IGVFFI3661DYCZ/",
"/sequence-files/IGVFFI3404TNRB/",
"/sequence-files/IGVFFI5618KJTL/",
"/sequence-files/IGVFFI9938RSGJ/",
"/sequence-files/IGVFFI2101LUKA/",
"/sequence-files/IGVFFI3822FKWU/",
"/sequence-files/IGVFFI5856MBZY/",
"/sequence-files/IGVFFI1923TAJO/",
"/sequence-files/IGVFFI2692RLBL/",
"/sequence-files/IGVFFI3781WUCJ/",
"/sequence-files/IGVFFI4037MADE/",
"/sequence-files/IGVFFI5652BFRM/",
"/sequence-files/IGVFFI0563CMOK/",
"/sequence-files/IGVFFI4084SMWN/",
"/sequence-files/IGVFFI8729GGIK/",
"/sequence-files/IGVFFI6786SIBQ/",
"/sequence-files/IGVFFI6704ZGKA/",
"/sequence-files/IGVFFI2742ZBCO/",
"/sequence-files/IGVFFI3441DWDI/",
"/sequence-files/IGVFFI3737JPIC/",
"/sequence-files/IGVFFI2273KVNE/",
"/sequence-files/IGVFFI8069CLVK/",
"/sequence-files/IGVFFI9124DLHT/",
"/sequence-files/IGVFFI2156FMIM/",
"/sequence-files/IGVFFI3111ZTFQ/",
"/sequence-files/IGVFFI3941EDMO/",
"/sequence-files/IGVFFI0335PKVW/",
"/sequence-files/IGVFFI1191SLYV/",
"/sequence-files/IGVFFI0430QIYR/",
"/sequence-files/IGVFFI2854ASCP/",
"/sequence-files/IGVFFI4723EUCH/",
"/sequence-files/IGVFFI1921EAAC/",
"/sequence-files/IGVFFI1963CRUV/",
"/sequence-files/IGVFFI5413LBSV/",
"/sequence-files/IGVFFI2178RNXL/",
"/sequence-files/IGVFFI3073SRFG/",
"/sequence-files/IGVFFI5554GZZL/",
"/sequence-files/IGVFFI1676TAZU/",
"/sequence-files/IGVFFI6510OQHN/",
"/sequence-files/IGVFFI7505QDXY/",
"/sequence-files/IGVFFI7772IJYG/",
"/sequence-files/IGVFFI6188YZVA/",
"/sequence-files/IGVFFI0670DLLR/",
"/sequence-files/IGVFFI9096HAIF/",
"/sequence-files/IGVFFI5225AWLF/",
"/sequence-files/IGVFFI0510MBXY/",
"/sequence-files/IGVFFI4854VPOB/",
"/sequence-files/IGVFFI8548CKRB/",
"/sequence-files/IGVFFI3229ADVR/",
"/sequence-files/IGVFFI4604RVST/",
"/sequence-files/IGVFFI0431ZBFI/",
"/sequence-files/IGVFFI0134ZAII/",
"/sequence-files/IGVFFI1920HJWM/",
"/sequence-files/IGVFFI3341ASXS/",
"/sequence-files/IGVFFI0306ZBHP/",
"/sequence-files/IGVFFI9356YEYC/",
"/sequence-files/IGVFFI5839LZHZ/",
"/sequence-files/IGVFFI9050PVKW/",
"/sequence-files/IGVFFI5156POEH/",
"/sequence-files/IGVFFI6082RSWE/",
"/sequence-files/IGVFFI6383STLI/",
"/sequence-files/IGVFFI4705JLJV/",
"/sequence-files/IGVFFI7694KDEC/",
"/sequence-files/IGVFFI1392RWVG/",
"/sequence-files/IGVFFI3426YZUR/",
"/sequence-files/IGVFFI2428SEUH/",
"/sequence-files/IGVFFI7648TIYB/",
"/sequence-files/IGVFFI6079KHVH/",
"/sequence-files/IGVFFI2551MBUE/",
"/sequence-files/IGVFFI3771GJUQ/",
"/sequence-files/IGVFFI5442CVUH/",
"/sequence-files/IGVFFI4596MWER/",
"/sequence-files/IGVFFI7964YXUR/",
"/sequence-files/IGVFFI0730WYAI/",
"/sequence-files/IGVFFI5760KHNI/",
"/sequence-files/IGVFFI8794RMUN/",
"/sequence-files/IGVFFI0285XXVB/",
"/sequence-files/IGVFFI4467NZMS/",
"/sequence-files/IGVFFI3628JSCJ/",
"/sequence-files/IGVFFI3355LHJX/",
"/sequence-files/IGVFFI9450AFXS/",
"/sequence-files/IGVFFI9455QXMF/",
"/sequence-files/IGVFFI1177KQUE/",
"/sequence-files/IGVFFI7065LEVK/",
"/sequence-files/IGVFFI2310RUWX/",
"/sequence-files/IGVFFI2347FUYM/",
"/sequence-files/IGVFFI9201QQSP/",
"/sequence-files/IGVFFI6274RIGQ/",
"/sequence-files/IGVFFI3495YIJJ/",
"/sequence-files/IGVFFI1005TVNZ/",
"/sequence-files/IGVFFI5580MKTE/",
"/sequence-files/IGVFFI3107AONJ/",
"/sequence-files/IGVFFI4973HJTR/",
"/sequence-files/IGVFFI1861NXIO/",
"/sequence-files/IGVFFI5150XDHC/",
"/sequence-files/IGVFFI8334ZDLG/",
"/sequence-files/IGVFFI4565RAGM/",
"/sequence-files/IGVFFI9350FOAA/",
"/sequence-files/IGVFFI7400OMWM/",
"/sequence-files/IGVFFI9024ARMC/",
"/sequence-files/IGVFFI9703ZTWT/",
"/sequence-files/IGVFFI7017DGWG/",
"/sequence-files/IGVFFI7582UILO/",
"/sequence-files/IGVFFI2681TJMH/",
"/sequence-files/IGVFFI0178LNUJ/",
"/sequence-files/IGVFFI0031YHLP/",
"/sequence-files/IGVFFI0406DXRA/",
"/sequence-files/IGVFFI8801LKZU/",
"/sequence-files/IGVFFI9693MAZJ/",
"/sequence-files/IGVFFI3551INOW/",
"/sequence-files/IGVFFI5005CQTZ/",
"/sequence-files/IGVFFI8662TOEU/",
"/sequence-files/IGVFFI7505DXPP/",
"/sequence-files/IGVFFI8221RBTX/",
"/sequence-files/IGVFFI3113YRNY/",
"/sequence-files/IGVFFI0443KUJF/",
"/sequence-files/IGVFFI0374MRGH/",
"/sequence-files/IGVFFI8467TYUI/",
"/sequence-files/IGVFFI0993LGBN/",
"/sequence-files/IGVFFI1930HVWJ/",
"/sequence-files/IGVFFI0085RBIX/",
"/sequence-files/IGVFFI9512OYDF/",
"/sequence-files/IGVFFI0180WHXS/",
"/sequence-files/IGVFFI7501ZALX/",
"/sequence-files/IGVFFI4722CNVL/",
"/sequence-files/IGVFFI7431RCGP/",
"/sequence-files/IGVFFI6026BVRJ/",
"/sequence-files/IGVFFI6476KKYA/",
"/sequence-files/IGVFFI4621AWTZ/",
"/sequence-files/IGVFFI9512DOCW/",
"/sequence-files/IGVFFI5015ASYV/",
"/sequence-files/IGVFFI7274ZVUO/",
"/sequence-files/IGVFFI9138RFUI/",
"/sequence-files/IGVFFI0478MTGC/",
"/sequence-files/IGVFFI4926VZKS/",
"/sequence-files/IGVFFI7018SHCD/",
"/sequence-files/IGVFFI5726TPBT/",
"/sequence-files/IGVFFI5351SZWH/",
"/sequence-files/IGVFFI9899BCVQ/",
"/sequence-files/IGVFFI4069GOTP/",
"/sequence-files/IGVFFI0927GWFP/",
"/sequence-files/IGVFFI0642GUTH/",
"/sequence-files/IGVFFI2260XLYB/",
"/sequence-files/IGVFFI6501BKRE/",
"/sequence-files/IGVFFI8567QUIK/",
"/sequence-files/IGVFFI3932SFXT/",
"/sequence-files/IGVFFI5536RKMS/",
"/sequence-files/IGVFFI3098QMSQ/",
"/sequence-files/IGVFFI7522EURJ/",
"/sequence-files/IGVFFI4485AMSF/",
"/sequence-files/IGVFFI0317PNSO/",
"/sequence-files/IGVFFI1401TKFW/",
"/sequence-files/IGVFFI4336XZGU/",
"/sequence-files/IGVFFI3645OCFN/",
"/sequence-files/IGVFFI3726KVYY/",
"/sequence-files/IGVFFI4281WUKU/",
"/sequence-files/IGVFFI6593GEUJ/",
"/sequence-files/IGVFFI3168EMCS/",
"/sequence-files/IGVFFI9398QUEG/",
"/sequence-files/IGVFFI6533QYYG/",
"/sequence-files/IGVFFI0741KCBH/",
"/sequence-files/IGVFFI4436DTNQ/",
"/sequence-files/IGVFFI9940LGAW/",
"/sequence-files/IGVFFI2824UEMJ/",
"/sequence-files/IGVFFI5613NTJJ/",
"/sequence-files/IGVFFI5037AWWW/",
"/sequence-files/IGVFFI2820LSQY/",
"/sequence-files/IGVFFI8203STDB/",
"/sequence-files/IGVFFI6027QDCZ/",
"/sequence-files/IGVFFI5022QTZJ/",
"/sequence-files/IGVFFI2801WFFR/",
"/sequence-files/IGVFFI7378BZUL/",
"/sequence-files/IGVFFI1735WJCM/",
"/sequence-files/IGVFFI1666KGAL/",
"/sequence-files/IGVFFI8932WAEO/",
"/sequence-files/IGVFFI4820UTCR/",
"/sequence-files/IGVFFI3067OHXB/",
"/sequence-files/IGVFFI5107FNAF/",
"/sequence-files/IGVFFI1474NQRY/",
"/sequence-files/IGVFFI0779URUE/",
"/sequence-files/IGVFFI8566WHOR/",
"/sequence-files/IGVFFI6496PUWJ/",
"/sequence-files/IGVFFI9210FKJW/",
"/sequence-files/IGVFFI7511SZAY/",
"/sequence-files/IGVFFI3912UHZL/",
"/sequence-files/IGVFFI7295ORRO/",
"/sequence-files/IGVFFI4036POXY/",
"/sequence-files/IGVFFI8726ULXT/"
],
"file_format": "tsv",
"file_format_specifications": [
{
"@id": "/documents/73fdecf2-a1d2-4f13-9fe1-fe449054aacc/",
"description": "explanation of columns in analysis summary file output by the Variant-EFFECTS pipeline"
}
],
"file_set": {
"@id": "/analysis-sets/IGVFDS1132MKHT/",
"@type": [
"AnalysisSet",
"FileSet",
"Item"
],
"accession": "IGVFDS1132MKHT",
"data_use_limitation_summaries": [
"no certificate"
],
"file_set_type": "principal analysis",
"samples": [
{
"@id": "/in-vitro-systems/IGVFSM4927UHAC/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM4927UHAC",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 51-75% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM8432ARFA/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM8432ARFA",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 51-75% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM8935ZBHB/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM8935ZBHB",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 26-50% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM8685IQCU/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM8685IQCU",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM7132GAPK/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM7132GAPK",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 76-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM7281WHSE/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM7281WHSE",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 51-75% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM5494BFWK/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM5494BFWK",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM9443MCAM/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM9443MCAM",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 76-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM2543EYOC/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM2543EYOC",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 76-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM8787PPBP/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM8787PPBP",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM2289HGEI/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM2289HGEI",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM7040CAHB/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM7040CAHB",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM9514CCZH/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM9514CCZH",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 76-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM2125QBFY/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM2125QBFY",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 26-50% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM0397MOBU/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM0397MOBU",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM3742TXQB/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM3742TXQB",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM3944GUBH/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM3944GUBH",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM7733IXMO/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM7733IXMO",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM4813DYRJ/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM4813DYRJ",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 26-50% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM5477MOJC/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM5477MOJC",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 51-75% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM1066TJDA/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM1066TJDA",
"classifications": [
"cell line"
],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released",
"summary": "CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"status": "released",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 26-50% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
}
],
"status": "preview",
"summary": "CRISPR prime editing Variant-EFFECTS targeting PPIF integrating a guide (sgRNA) library targeting sequence variants in a genomic locus"
},
"file_size": 268,
"gene_list_for": [],
"href": "/tabular-files/IGVFFI4434LXUU/@@download/IGVFFI4434LXUU.tsv.gz",
"input_file_for": [
"/tabular-files/IGVFFI1254NFRS/"
],
"integrated_in": [],
"lab": {
"@id": "/labs/jesse-engreitz/",
"title": "Jesse Engreitz, Stanford"
},
"loci_list_for": [],
"md5sum": "569b674ef94a9742b2a2a29f8248567e",
"primer_design_for": [],
"quality_metrics": [],
"s3_uri": "s3://igvf-files/2024/12/17/3bfdb2e6-a7e6-4a41-be81-1aed9009f51f/IGVFFI4434LXUU.tsv.gz",
"schema_version": "15",
"status": "preview",
"submitted_by": {
"@id": "/users/f9e7cd82-a407-4a20-89ee-f4dc668b0cbe/",
"title": "Michael Montgomery"
},
"submitted_file_name": "PPIF_5PrimeSpliceIndividual_AGGT_CAAC_AllelicEffectsStats.tsv.gz",
"summary": "hg19 variant effects",
"upload_status": "validated",
"uuid": "3bfdb2e6-a7e6-4a41-be81-1aed9009f51f",
"workflow": {
"@id": "/workflows/IGVFWF0099SJHI/",
"name": "Variant-EFFECTS Pipeline",
"uniform_pipeline": false
}
}