{
"@context": "/terms/",
"@id": "/tabular-files/IGVFFI4223LNAY/",
"@type": [
"TabularFile",
"File",
"Item"
],
"accession": "IGVFFI4223LNAY",
"aliases": [
"charles-gersbach:cd8-tcell-ko-nt-grnas-metadata"
],
"assay_titles": [],
"assembly": "GRCh38",
"audit": {
"INTERNAL_ACTION": [
{
"category": "mismatched status",
"detail": "Released tabular file [IGVFFI4223LNAY](/tabular-files/IGVFFI4223LNAY/) has in progress subobject curated set [IGVFDS1053LAWX](/curated-sets/IGVFDS1053LAWX/).",
"level": 30,
"level_name": "INTERNAL_ACTION",
"name": "audit_item_status",
"path": "/tabular-files/IGVFFI4223LNAY/"
}
],
"NOT_COMPLIANT": [
{
"category": "missing file format specifications",
"detail": "Tabular file [IGVFFI4223LNAY](/tabular-files/IGVFFI4223LNAY/) has no `file_format_specifications`. Tabular files are expected to link to a file format specifications document describing the headers of the file.",
"level": 50,
"level_name": "NOT_COMPLIANT",
"name": "audit_file_no_file_format_specifications",
"path": "/tabular-files/IGVFFI4223LNAY/"
}
]
},
"award": {
"@id": "/awards/HG012053/",
"component": "functional characterization"
},
"barcode_map_for": [],
"checkfiles_version": "v14",
"content_md5sum": "6c8839d158273dcb5695cc689b0a8823",
"content_type": "guide RNA sequences",
"controlled_access": false,
"creation_timestamp": "2024-06-18T19:40:48.537753+00:00",
"file_format": "tsv",
"file_set": {
"@id": "/curated-sets/IGVFDS1053LAWX/",
"accession": "IGVFDS1053LAWX",
"file_set_type": "guide RNAs",
"samples": [
{
"@id": "/primary-cells/IGVFSM6537MPGY/",
"accession": "IGVFSM6537MPGY",
"classifications": [
"primary cell"
],
"modifications": [
{
"@id": "/crispr-modifications/9fef21f2-9727-4a97-a5a7-c590a637c101/",
"modality": "knockout",
"status": "released",
"summary": "CRISPRko Sp-Cas9"
}
],
"sample_terms": [
{
"@id": "/sample-terms/CL_0000909/",
"status": "released",
"term_name": "CD8-positive, alpha-beta memory T cell"
}
],
"status": "released",
"summary": "CD8-positive, alpha-beta memory T cell, Homo sapiens modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4)",
"taxa": "Homo sapiens"
},
{
"@id": "/primary-cells/IGVFSM1498WFCO/",
"accession": "IGVFSM1498WFCO",
"classifications": [
"primary cell"
],
"modifications": [
{
"@id": "/crispr-modifications/9fef21f2-9727-4a97-a5a7-c590a637c101/",
"modality": "knockout",
"status": "released",
"summary": "CRISPRko Sp-Cas9"
}
],
"sample_terms": [
{
"@id": "/sample-terms/CL_0000909/",
"status": "released",
"term_name": "CD8-positive, alpha-beta memory T cell"
}
],
"status": "released",
"summary": "CD8-positive, alpha-beta memory T cell, Homo sapiens modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4)",
"taxa": "Homo sapiens"
},
{
"@id": "/primary-cells/IGVFSM0383IKGE/",
"accession": "IGVFSM0383IKGE",
"classifications": [
"primary cell"
],
"modifications": [
{
"@id": "/crispr-modifications/9fef21f2-9727-4a97-a5a7-c590a637c101/",
"modality": "knockout",
"status": "released",
"summary": "CRISPRko Sp-Cas9"
}
],
"sample_terms": [
{
"@id": "/sample-terms/CL_0000909/",
"status": "released",
"term_name": "CD8-positive, alpha-beta memory T cell"
}
],
"status": "released",
"summary": "CD8-positive, alpha-beta memory T cell, Homo sapiens modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4)",
"taxa": "Homo sapiens"
}
],
"status": "in progress",
"summary": "Homo sapiens GRCh38 guide RNAs",
"taxa": "Homo sapiens"
},
"file_size": 170,
"gene_list_for": [],
"href": "/tabular-files/IGVFFI4223LNAY/@@download/IGVFFI4223LNAY.tsv.gz",
"input_file_for": [],
"integrated_in": [
{
"@id": "/construct-library-sets/IGVFDS9830PJVQ/",
"file_set_type": "guide library",
"status": "released",
"summary": "non-targeting guide (sgRNA) library"
}
],
"lab": {
"@id": "/labs/charles-gersbach/",
"title": "Charles Gersbach, Duke"
},
"loci_list_for": [],
"md5sum": "f43b04d736e15b85a589b833b27159a8",
"quality_metrics": [],
"release_timestamp": "2025-02-05T21:27:56.893705+00:00",
"s3_uri": "s3://igvf-files/2024/06/18/ab5ec04e-e530-45a8-8fb5-be6bebfb4d0e/IGVFFI4223LNAY.tsv.gz",
"schema_version": "13",
"status": "released",
"submitted_by": {
"@id": "/users/29f5f78d-ac90-421e-90c6-a90e1dc407a7/",
"title": "Alejandro Barrera"
},
"submitted_file_name": "/data/reddylab/Alex/IGVF/data_submissions/reference_data/AIM_2_T_cell_project_1/cas9_ko.nt.igvf_metadata.v3.txt.gz",
"summary": "GRCh38 guide RNA sequences",
"upload_status": "validated",
"uuid": "ab5ec04e-e530-45a8-8fb5-be6bebfb4d0e"
}