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2 items
  • principal
    AnalysisSet
    IGVFDS0021NCLH
    CRISPR base editing FACS screen: guide quantifications, variant effects
    Richard Sherwood, Brigham and Women's Hospital
    Samples
    HepG2 cell line, modified with CRISPR modifications, transfected with a guide library, sorted into bins
    released
  • MeasurementSet
    IGVFDS4638GTKE
    CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
    Richard Sherwood, Brigham and Women's Hospital
    Sample Summary
    HepG2 cell line, male, Homo sapiens modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
    released