CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Bottom 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS2333QYKL
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Top 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS8056EBUX
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS1445OKMY
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Top 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS3623JPJT
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Bottom 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS8455NAPR
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Bottom 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS6636PQMX
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Top 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS4638GTKE
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS3068SPQU
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS2124SNCK
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Top 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS7718HEXQ
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Top 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS2884DTLZ
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Bottom 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS5856FVYJ
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Top 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS7237TBXX
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Bottom 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS9030KZWL
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Top 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS7513KJPR
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS4552QTII
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Bottom 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS0737ROIQ
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Bottom 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS4235CEEA
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Bottom 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
released
MeasurementSet
IGVFDS5442FZSA
CRISPR base editing FACS screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide
Richard Sherwood, Brigham and Women's Hospital
Sample Summary
HepG2 cell line, male, Homo sapiens (sorting details: Sorted for Top 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)