nCas9

Streptococcus pyogenes (Sp)

M-MLV RT (PE2)

prime editing

CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)

fc6bc0b3-a064-47d0-b95d-a9af14bb1624

dCas9

Streptococcus pyogenes (Sp)

VP64

activation

addgene:61422

CRISPRa Sp-dCas9-VP64

ee99bf66-2a5a-4ec6-8380-9434b259afd1

dCas9

Streptococcus pyogenes (Sp)

KOX1-KRAB

interference

addgene:85449

CRISPRi Sp-dCas9-KOX1-KRAB

b4bc725a-8eeb-4180-9789-bece3516c0c1

Cas9

Streptococcus pyogenes (Sp)

knockout

addgene:162335

CRISPRko Sp-Cas9

9fef21f2-9727-4a97-a5a7-c590a637c101

dCas9

Staphylococcus aureus (Sa)

interference

addgene:194278

CRISPRi Sa-dCas9

95393c9a-637d-43f6-baf9-662e45d28d61

AID

degradation

AID system targeting RAD21

95081d1b-08b4-49ed-b324-e53fc43d8456

dCas9

Streptococcus pyogenes (Sp)

VP64-p65-Rta (VPR)

activation

CRISPRa Sp-dCas9-VP64-p65-Rta (VPR)

8b61bce4-105c-435e-9b32-1c8903566a9b

dCas9

Streptococcus pyogenes (Sp)

KOX1-KRAB

interference

CRISPRi Sp-dCas9-KOX1-KRAB

8543fa06-1720-4e7d-8e8f-7e24c1b1cf79

dCas9

Staphylococcus aureus (Sa)

2xVP64

activation

addgene:194279

CRISPRa Sa-dCas9-2xVP64

4c532ce1-11aa-41be-9757-13923c19248b

dCas9

Streptococcus pyogenes (Sp)

VPH

activation

addgene:158091

CRISPRa Sp-dCas9-VPH

426a4099-35d9-4c65-8851-5e788a3d4e70

AID

degradation

inactive AID system targeting RAD21

2e8d10cc-fc98-44d5-a7d9-e2892e16c98a

dCas9

Staphylococcus aureus (Sa)

VP64

activation

addgene:115790

CRISPRa Sa-dCas9-VP64

2c49eb31-f10b-47b7-b260-4f720014ad79