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12 items
ID
Cas
Cas Species
Degron System
Fused Domain
Lab
Modality
Product ID
Summary
Tagged Proteins
UUID
/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/
nCas9
Streptococcus pyogenes (Sp)
M-MLV RT (PE2)
/labs/jesse-engreitz/
prime editing
CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)
fc6bc0b3-a064-47d0-b95d-a9af14bb1624
/crispr-modifications/ee99bf66-2a5a-4ec6-8380-9434b259afd1/
dCas9
Streptococcus pyogenes (Sp)
VP64
/labs/jay-shendure/
activation
addgene:61422
CRISPRa Sp-dCas9-VP64
ee99bf66-2a5a-4ec6-8380-9434b259afd1
/crispr-modifications/b4bc725a-8eeb-4180-9789-bece3516c0c1/
dCas9
Streptococcus pyogenes (Sp)
KOX1-KRAB
/labs/jesse-engreitz/
interference
addgene:85449
CRISPRi Sp-dCas9-KOX1-KRAB
b4bc725a-8eeb-4180-9789-bece3516c0c1
/crispr-modifications/9fef21f2-9727-4a97-a5a7-c590a637c101/
Cas9
Streptococcus pyogenes (Sp)
/labs/charles-gersbach/
knockout
addgene:162335
CRISPRko Sp-Cas9
9fef21f2-9727-4a97-a5a7-c590a637c101
/crispr-modifications/95393c9a-637d-43f6-baf9-662e45d28d61/
dCas9
Staphylococcus aureus (Sa)
/labs/charles-gersbach/
interference
addgene:194278
CRISPRi Sa-dCas9
95393c9a-637d-43f6-baf9-662e45d28d61
/degron-modifications/95081d1b-08b4-49ed-b324-e53fc43d8456/
AID
/labs/jesse-engreitz/
degradation
AID system targeting RAD21
/genes/ENSG00000164754/
95081d1b-08b4-49ed-b324-e53fc43d8456
/crispr-modifications/8b61bce4-105c-435e-9b32-1c8903566a9b/
dCas9
Streptococcus pyogenes (Sp)
VP64-p65-Rta (VPR)
/labs/jay-shendure/
activation
CRISPRa Sp-dCas9-VP64-p65-Rta (VPR)
8b61bce4-105c-435e-9b32-1c8903566a9b
/crispr-modifications/8543fa06-1720-4e7d-8e8f-7e24c1b1cf79/
dCas9
Streptococcus pyogenes (Sp)
KOX1-KRAB
/labs/jesse-engreitz/
interference
CRISPRi Sp-dCas9-KOX1-KRAB
8543fa06-1720-4e7d-8e8f-7e24c1b1cf79
/crispr-modifications/4c532ce1-11aa-41be-9757-13923c19248b/
dCas9
Staphylococcus aureus (Sa)
2xVP64
/labs/charles-gersbach/
activation
addgene:194279
CRISPRa Sa-dCas9-2xVP64
4c532ce1-11aa-41be-9757-13923c19248b
/crispr-modifications/426a4099-35d9-4c65-8851-5e788a3d4e70/
dCas9
Streptococcus pyogenes (Sp)
VPH
/labs/jay-shendure/
activation
addgene:158091
CRISPRa Sp-dCas9-VPH
426a4099-35d9-4c65-8851-5e788a3d4e70
/degron-modifications/2e8d10cc-fc98-44d5-a7d9-e2892e16c98a/
AID
/labs/jesse-engreitz/
degradation
inactive AID system targeting RAD21
/genes/ENSG00000164754/
2e8d10cc-fc98-44d5-a7d9-e2892e16c98a
/crispr-modifications/2c49eb31-f10b-47b7-b260-4f720014ad79/
dCas9
Staphylococcus aureus (Sa)
VP64
/labs/charles-gersbach/
activation
addgene:115790
CRISPRa Sa-dCas9-VP64
2c49eb31-f10b-47b7-b260-4f720014ad79