intermediate analysis

GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library

HiCAR: contact matrix

Hi-C assay

experimental data

HiCAR

GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library

CRISPR HiCAR integrating a non-targeting guide (sgRNA) library

principal analysis

GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library

HiCAR: bin paired count, differential chromatin contact quantifications

principal analysis

GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens treated with 1 μM Endothelin-1 for 3 days, transfected with a guide library

HiCAR: bin paired count, differential chromatin contact quantifications