in vitro CRISPR screen assay

experimental data

Proliferation CRISPR screen

Homo sapiens (female) TeloHAEC cell line modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library

Proliferation CRISPR base editing screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide associated with blood pressure

principal analysis

Homo sapiens (female) TeloHAEC cell line modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library

Homo sapiens TeloHAEC cell line, modified with CRISPR base editing SpRY-ABE8e, transfected with a guide library

Proliferation CRISPR base editing screen: guide quantifications