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Luca Pinello

Comprehensive characterization of variants underlying heart and blood diseases with CRISPR base editing

Guillaume Lettre, MHI

Homo sapiens TeloHAEC cell line, modified with CRISPRi Sp-dCas9-KOX1-KRAB, transfected with a guide library

Homo sapiens (female) TeloHAEC cell line modified with CRISPRi Sp-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library

Proliferation CRISPR interference screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide associated with blood pressure: guide quantifications

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Description

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Taxa

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Measured Mechanism

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Prediction Objects

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Protocols

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Samples

Sample Institutional Certificates

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Construct Library Data

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Sample

Modification

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Construct Library Design

Data Use Limitation

Audit Category: Internal Action

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Report