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Gary Hon

Multiscale functional characterization of genomic variation in human developmental disorders

Gary Hon, UT

Perturb-seq

guide (sgRNA) library targeting accessible genome regions in many genomic loci

GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW428), male, Homo sapiens modified with CRISPRi Sp-dCas9, transduced (lentivirus) with a guide library

CRISPR interference Perturb-seq integrating a guide (sgRNA) library targeting accessible genome regions in many genomic loci

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Functional Assay Mechanisms

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Cellular Transformation Target

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Audit category: WARNING

Externally Hosted

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