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CRISPRa Sp-dCas9-VP64-p65-Rta (VPR)

released
Summary
CRISPRa Sp-dCas9-VP64-p65-Rta (VPR)
Modality
activation
Cas
dCas9
Cas Species
Streptococcus pyogenes (Sp)
Fused Domain
VP64-p65-Rta (VPR)
Description
dCas9-VPR-005
Sources
horizondiscovery
Aliases
igvf:replacement_of_ec803a15-a3c1-4d14-b1be-be3a5ea1ef8a
jay-shendure:dCas9-VPR-005
Submitter Comment
This Crispr Modification is an identical replacement of the previously submitted Modification ec803a15-a3c1-4d14-b1be-be3a5ea1ef8a.

Biosamples Modified by this Modification

3 items
Sample Terms
Summary
InVitroSystem
K562 cell line (cellular sub pool: 10Xlane1), female, Homo sapiens modified with CRISPRa Sp-dCas9-VP64-p65-Rta (VPR), transfected with a guide library
InVitroSystem
K562 cell line, female, Homo sapiens modified with CRISPRa Sp-dCas9-VP64-p65-Rta (VPR), transfected with a guide library
InVitroSystem
K562 cell line (cellular sub pool: 10Xlane2), female, Homo sapiens modified with CRISPRa Sp-dCas9-VP64-p65-Rta (VPR), transfected with a guide library

Attribution

Award
HG011966
Principal Investigator(s)
Contact P.I.
Jay Shendure
Lab
Jay Shendure, UW