{
"@context": "/terms/",
"@id": "/analysis-sets/IGVFDS8267JJHO/",
"@type": [
"AnalysisSet",
"FileSet",
"Item"
],
"accession": "IGVFDS8267JJHO",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1_Variant-EFFECTS_analysis"
],
"assay_titles": [
"Variant-EFFECTS"
],
"audit": {},
"award": {
"@id": "/awards/HG011972/",
"component": "functional characterization",
"contact_pi": {
"@id": "/users/6c75dbfa-635e-4a7a-8ec8-9e51e9c380a4/",
"title": "Jesse Engreitz"
},
"title": "Stanford Center for Connecting DNA Variants to Function and Phenotype"
},
"construct_library_sets": [
{
"@id": "/construct-library-sets/IGVFDS9097TEUZ/",
"accession": "IGVFDS9097TEUZ",
"file_set_type": "guide library",
"status": "preview",
"summary": "guide (sgRNA) library targeting sequence variants in a genomic locus"
}
],
"control_for": [],
"creation_timestamp": "2024-12-10T23:54:41.977703+00:00",
"data_use_limitation_summaries": [
"no certificate"
],
"donors": [
{
"@id": "/human-donors/IGVFDO7359LVPI/",
"accession": "IGVFDO7359LVPI",
"aliases": [
"igvf:donor_of_THP1"
],
"sex": "male",
"status": "released",
"taxa": "Homo sapiens"
}
],
"file_set_type": "principal analysis",
"files": [
{
"@id": "/tabular-files/IGVFFI2879FWTA/",
"accession": "IGVFFI2879FWTA",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1_Variant-EFFECTS_variant_effects_file"
],
"assembly": "hg19",
"content_type": "variant effects",
"controlled_access": false,
"creation_timestamp": "2024-12-17T21:04:05.768697+00:00",
"derived_from": [
"/sequence-files/IGVFFI6093XUML/",
"/sequence-files/IGVFFI6312XNKA/",
"/sequence-files/IGVFFI2762CXGD/",
"/sequence-files/IGVFFI4512GXQB/",
"/sequence-files/IGVFFI4633NSNS/",
"/sequence-files/IGVFFI5203ASJX/",
"/sequence-files/IGVFFI1730LSFI/",
"/sequence-files/IGVFFI8943LRHK/",
"/sequence-files/IGVFFI1580JGXL/",
"/sequence-files/IGVFFI2053LCMY/",
"/sequence-files/IGVFFI1404FVNO/",
"/sequence-files/IGVFFI3921TIMQ/",
"/sequence-files/IGVFFI3877IHZY/",
"/sequence-files/IGVFFI4133UGAH/",
"/sequence-files/IGVFFI8330OKPM/",
"/sequence-files/IGVFFI3646MPQX/",
"/sequence-files/IGVFFI5215NCRX/",
"/sequence-files/IGVFFI1735MSVI/",
"/sequence-files/IGVFFI9152WLRQ/",
"/sequence-files/IGVFFI3354ARKM/",
"/sequence-files/IGVFFI8745IIPC/",
"/sequence-files/IGVFFI4118FMML/",
"/sequence-files/IGVFFI6376VPVL/",
"/sequence-files/IGVFFI6091INMJ/",
"/sequence-files/IGVFFI0342VVJB/",
"/sequence-files/IGVFFI2355JZHP/",
"/sequence-files/IGVFFI5177ZOLM/",
"/sequence-files/IGVFFI6438GAEJ/",
"/sequence-files/IGVFFI5070JGVH/",
"/sequence-files/IGVFFI8930FNJO/",
"/sequence-files/IGVFFI8864MWDG/",
"/sequence-files/IGVFFI2636JFIL/",
"/sequence-files/IGVFFI2908POKO/",
"/sequence-files/IGVFFI8973RANO/",
"/sequence-files/IGVFFI5042FABZ/",
"/sequence-files/IGVFFI6580QZLE/",
"/sequence-files/IGVFFI0230MWGZ/",
"/sequence-files/IGVFFI8394PCPT/",
"/sequence-files/IGVFFI5834TSVP/",
"/sequence-files/IGVFFI5324EHDP/",
"/sequence-files/IGVFFI7793FABD/",
"/sequence-files/IGVFFI0757VOLL/",
"/sequence-files/IGVFFI1679CCWA/",
"/sequence-files/IGVFFI8432PVGB/",
"/sequence-files/IGVFFI3426ZZRH/",
"/sequence-files/IGVFFI6147GRJG/",
"/sequence-files/IGVFFI8192FBID/",
"/sequence-files/IGVFFI1645OSGA/",
"/sequence-files/IGVFFI6133KMKP/",
"/sequence-files/IGVFFI3285JBHG/",
"/sequence-files/IGVFFI4267BOIG/",
"/sequence-files/IGVFFI6236NXQF/",
"/sequence-files/IGVFFI0624APNL/",
"/sequence-files/IGVFFI5672DRHT/",
"/sequence-files/IGVFFI7420WWFW/",
"/sequence-files/IGVFFI4520ZRFQ/",
"/sequence-files/IGVFFI4645TQFL/",
"/sequence-files/IGVFFI2422VJHP/",
"/sequence-files/IGVFFI7692LFIS/",
"/sequence-files/IGVFFI7476JYCZ/",
"/sequence-files/IGVFFI5702PEUQ/",
"/sequence-files/IGVFFI2262GSCY/",
"/sequence-files/IGVFFI7300EEOB/",
"/sequence-files/IGVFFI0963IRWD/",
"/sequence-files/IGVFFI2441NZNR/",
"/sequence-files/IGVFFI0956MTMM/",
"/sequence-files/IGVFFI8167AOAP/",
"/sequence-files/IGVFFI2590EALV/",
"/sequence-files/IGVFFI3935MWVB/",
"/sequence-files/IGVFFI5160MLNZ/",
"/sequence-files/IGVFFI8889XXPJ/",
"/sequence-files/IGVFFI4022ZOEI/",
"/sequence-files/IGVFFI5855JQEM/",
"/sequence-files/IGVFFI0554NFJM/",
"/sequence-files/IGVFFI0456XDRV/",
"/sequence-files/IGVFFI2599PWZT/",
"/sequence-files/IGVFFI7500IIHI/",
"/sequence-files/IGVFFI7102RVTN/",
"/sequence-files/IGVFFI0581UNCQ/",
"/sequence-files/IGVFFI7786PDBQ/",
"/sequence-files/IGVFFI2119GFAZ/",
"/sequence-files/IGVFFI7863MFAT/",
"/sequence-files/IGVFFI4223QPVZ/",
"/sequence-files/IGVFFI0220IUQX/",
"/sequence-files/IGVFFI3973DVGN/",
"/sequence-files/IGVFFI1527ORNG/",
"/sequence-files/IGVFFI9549CUND/",
"/sequence-files/IGVFFI8610JHJL/",
"/sequence-files/IGVFFI1413MPDZ/",
"/sequence-files/IGVFFI1649DKNW/",
"/sequence-files/IGVFFI2505DQMC/",
"/sequence-files/IGVFFI1600GYCA/",
"/sequence-files/IGVFFI5404APZM/",
"/sequence-files/IGVFFI7015IOZQ/",
"/sequence-files/IGVFFI7686HUFV/",
"/sequence-files/IGVFFI6379UYXS/",
"/sequence-files/IGVFFI1191PFDC/",
"/sequence-files/IGVFFI6490OAXO/",
"/sequence-files/IGVFFI0481KBQJ/",
"/sequence-files/IGVFFI1874NAFS/",
"/sequence-files/IGVFFI4698ZIGI/",
"/sequence-files/IGVFFI0226FDXW/",
"/sequence-files/IGVFFI5480EKDI/",
"/sequence-files/IGVFFI4005MVIO/",
"/sequence-files/IGVFFI7856RWJE/",
"/sequence-files/IGVFFI8837INJP/",
"/sequence-files/IGVFFI8904UFIE/",
"/sequence-files/IGVFFI5503SSYE/",
"/sequence-files/IGVFFI7750ZXHQ/",
"/sequence-files/IGVFFI6978BBQS/",
"/sequence-files/IGVFFI1425FZBV/",
"/sequence-files/IGVFFI8573BTLD/",
"/sequence-files/IGVFFI7225QIED/",
"/sequence-files/IGVFFI6469CZBC/",
"/sequence-files/IGVFFI1577MHZT/",
"/sequence-files/IGVFFI5748GAQO/",
"/sequence-files/IGVFFI4071LLWH/",
"/sequence-files/IGVFFI0572LLKF/",
"/sequence-files/IGVFFI1517XLSH/",
"/sequence-files/IGVFFI1720KWYI/",
"/sequence-files/IGVFFI3250DRHR/",
"/sequence-files/IGVFFI0965TDOY/",
"/sequence-files/IGVFFI2890GIYA/",
"/sequence-files/IGVFFI2867MZFH/",
"/sequence-files/IGVFFI1584JSLG/",
"/sequence-files/IGVFFI0705VMDB/",
"/sequence-files/IGVFFI6873VMVY/",
"/sequence-files/IGVFFI3996DDJK/",
"/sequence-files/IGVFFI0177IBFC/",
"/sequence-files/IGVFFI9025DKAN/",
"/sequence-files/IGVFFI6565NPOG/",
"/sequence-files/IGVFFI1458GIKC/",
"/sequence-files/IGVFFI7417ZHAA/",
"/sequence-files/IGVFFI7449HGLT/",
"/sequence-files/IGVFFI7772PQMF/",
"/sequence-files/IGVFFI8170ZADS/",
"/sequence-files/IGVFFI6524OYQD/",
"/sequence-files/IGVFFI8641OHQI/",
"/sequence-files/IGVFFI7566NSNU/",
"/sequence-files/IGVFFI0288CLJP/",
"/sequence-files/IGVFFI0112KUGA/",
"/sequence-files/IGVFFI4353VTDP/",
"/sequence-files/IGVFFI5356CZGH/",
"/sequence-files/IGVFFI6680XGJX/",
"/sequence-files/IGVFFI3978NLOJ/",
"/sequence-files/IGVFFI9675WXCO/",
"/sequence-files/IGVFFI1306CCJS/",
"/sequence-files/IGVFFI1910FMHB/",
"/sequence-files/IGVFFI7913JZEI/",
"/sequence-files/IGVFFI1994WAGR/",
"/sequence-files/IGVFFI8444VXTJ/",
"/sequence-files/IGVFFI9659OWYG/",
"/sequence-files/IGVFFI1619FDED/",
"/sequence-files/IGVFFI4290XIZD/",
"/sequence-files/IGVFFI8923SAQP/",
"/sequence-files/IGVFFI2836ZXQS/",
"/sequence-files/IGVFFI1713BHRU/",
"/sequence-files/IGVFFI2168LTUH/",
"/sequence-files/IGVFFI4650XMXL/",
"/sequence-files/IGVFFI6301PNSH/",
"/sequence-files/IGVFFI2501PMCZ/",
"/sequence-files/IGVFFI3303NYCL/",
"/sequence-files/IGVFFI5132UCTK/",
"/sequence-files/IGVFFI3793ZIGN/",
"/sequence-files/IGVFFI3441INRD/",
"/sequence-files/IGVFFI5994FRPK/",
"/sequence-files/IGVFFI8961LTUC/",
"/sequence-files/IGVFFI2279QTVE/",
"/sequence-files/IGVFFI0689IVJP/",
"/sequence-files/IGVFFI2560IAJV/",
"/sequence-files/IGVFFI6050VEED/",
"/sequence-files/IGVFFI6550YREV/",
"/sequence-files/IGVFFI1575WZQE/",
"/sequence-files/IGVFFI0050OEKF/",
"/sequence-files/IGVFFI3439UFPF/",
"/sequence-files/IGVFFI4346OXSU/",
"/sequence-files/IGVFFI9820ZBNI/",
"/sequence-files/IGVFFI7451YGJF/",
"/sequence-files/IGVFFI7205ODIS/",
"/sequence-files/IGVFFI9120SEWL/",
"/sequence-files/IGVFFI9296NSBS/",
"/sequence-files/IGVFFI8974BICU/",
"/sequence-files/IGVFFI1897CJVK/",
"/sequence-files/IGVFFI0412UONO/",
"/sequence-files/IGVFFI2540CSBV/",
"/sequence-files/IGVFFI8245CWHJ/",
"/sequence-files/IGVFFI0770GBZI/",
"/sequence-files/IGVFFI2294HIIW/",
"/sequence-files/IGVFFI0730QGFV/",
"/sequence-files/IGVFFI6419WVIT/",
"/sequence-files/IGVFFI5327LCXF/",
"/sequence-files/IGVFFI9293PXFB/",
"/sequence-files/IGVFFI5452KYUV/",
"/sequence-files/IGVFFI7195TCPS/",
"/sequence-files/IGVFFI6815FYBC/",
"/sequence-files/IGVFFI6298WXNR/",
"/sequence-files/IGVFFI6803SSYG/",
"/sequence-files/IGVFFI6494JFJW/",
"/sequence-files/IGVFFI9908IDBB/",
"/sequence-files/IGVFFI9555YYPX/",
"/sequence-files/IGVFFI4346CZNZ/",
"/sequence-files/IGVFFI7768HWKL/",
"/sequence-files/IGVFFI6000GPAP/",
"/sequence-files/IGVFFI2652BFQT/",
"/sequence-files/IGVFFI0816MSXZ/",
"/sequence-files/IGVFFI1987SGXH/",
"/sequence-files/IGVFFI1020PGCU/",
"/sequence-files/IGVFFI3948ULIR/",
"/sequence-files/IGVFFI2910CSOZ/",
"/sequence-files/IGVFFI1248PWUP/",
"/sequence-files/IGVFFI7922BZCQ/",
"/sequence-files/IGVFFI7339DDFP/",
"/sequence-files/IGVFFI6046OPSN/",
"/sequence-files/IGVFFI6343FOJK/",
"/sequence-files/IGVFFI8987VMHI/",
"/sequence-files/IGVFFI7477WSWI/",
"/sequence-files/IGVFFI1016QHAL/",
"/sequence-files/IGVFFI2327NUYR/",
"/sequence-files/IGVFFI0785HVSM/",
"/sequence-files/IGVFFI9363URER/",
"/sequence-files/IGVFFI2610ZXCO/",
"/sequence-files/IGVFFI3569FRMY/",
"/sequence-files/IGVFFI3605KDPL/",
"/sequence-files/IGVFFI1401GOIJ/",
"/sequence-files/IGVFFI3587TOQQ/",
"/sequence-files/IGVFFI0158IOOJ/",
"/sequence-files/IGVFFI5330RZFM/",
"/sequence-files/IGVFFI4417EXSV/",
"/sequence-files/IGVFFI8125TOCY/",
"/sequence-files/IGVFFI8894LFSH/",
"/sequence-files/IGVFFI0332BJVY/",
"/sequence-files/IGVFFI2251MIMV/",
"/sequence-files/IGVFFI5882QZEJ/",
"/sequence-files/IGVFFI9479PZAP/",
"/sequence-files/IGVFFI3999EWBP/",
"/sequence-files/IGVFFI8971VXWD/",
"/sequence-files/IGVFFI2260XNAI/",
"/sequence-files/IGVFFI5461ROHI/",
"/sequence-files/IGVFFI4479TCTY/",
"/sequence-files/IGVFFI2650DEGZ/",
"/sequence-files/IGVFFI5638URJI/",
"/sequence-files/IGVFFI2448XSCE/",
"/sequence-files/IGVFFI9446RJVH/",
"/sequence-files/IGVFFI9946ZRHW/",
"/sequence-files/IGVFFI0710EULF/",
"/sequence-files/IGVFFI5253PKOS/",
"/sequence-files/IGVFFI9601NHXA/",
"/sequence-files/IGVFFI0477ULOX/",
"/sequence-files/IGVFFI6587SBOS/",
"/sequence-files/IGVFFI5755OFUB/",
"/sequence-files/IGVFFI5957HQCQ/",
"/sequence-files/IGVFFI1764YXEV/",
"/sequence-files/IGVFFI2119ZNHL/",
"/sequence-files/IGVFFI6058IOWZ/",
"/sequence-files/IGVFFI7948MXYU/",
"/sequence-files/IGVFFI3108RZXO/",
"/sequence-files/IGVFFI0680OMKD/",
"/sequence-files/IGVFFI0688DEHE/",
"/sequence-files/IGVFFI7724RGJB/",
"/sequence-files/IGVFFI7438BODM/",
"/sequence-files/IGVFFI1973HJRG/",
"/sequence-files/IGVFFI6901STBZ/",
"/sequence-files/IGVFFI7520DXYK/",
"/sequence-files/IGVFFI4922YXNX/",
"/sequence-files/IGVFFI4138DYOI/",
"/sequence-files/IGVFFI7556TJQR/",
"/sequence-files/IGVFFI2320SVSF/",
"/sequence-files/IGVFFI2941VGUJ/",
"/sequence-files/IGVFFI8101VHTK/",
"/sequence-files/IGVFFI7232PSDF/",
"/sequence-files/IGVFFI4388VEHJ/",
"/sequence-files/IGVFFI0012JHHF/",
"/sequence-files/IGVFFI8656CGMF/",
"/sequence-files/IGVFFI6875JCAQ/",
"/sequence-files/IGVFFI2774CULG/",
"/sequence-files/IGVFFI9170ZKMQ/",
"/sequence-files/IGVFFI8291XJRA/",
"/sequence-files/IGVFFI4064MEJN/",
"/sequence-files/IGVFFI4787HMIB/",
"/sequence-files/IGVFFI4528OFLS/",
"/sequence-files/IGVFFI4308MOXA/",
"/sequence-files/IGVFFI5046WQEQ/",
"/sequence-files/IGVFFI8379AGJY/",
"/sequence-files/IGVFFI6923VMCF/",
"/sequence-files/IGVFFI5791HFQF/",
"/sequence-files/IGVFFI3065IJVL/",
"/sequence-files/IGVFFI8657KPTP/",
"/sequence-files/IGVFFI5732TMGJ/",
"/sequence-files/IGVFFI1735WJCM/",
"/sequence-files/IGVFFI1666KGAL/",
"/sequence-files/IGVFFI8932WAEO/",
"/sequence-files/IGVFFI4820UTCR/",
"/sequence-files/IGVFFI3067OHXB/",
"/sequence-files/IGVFFI5107FNAF/",
"/sequence-files/IGVFFI1474NQRY/",
"/sequence-files/IGVFFI0779URUE/",
"/sequence-files/IGVFFI8566WHOR/",
"/sequence-files/IGVFFI6496PUWJ/",
"/sequence-files/IGVFFI9210FKJW/",
"/sequence-files/IGVFFI7511SZAY/",
"/sequence-files/IGVFFI3912UHZL/",
"/sequence-files/IGVFFI7295ORRO/",
"/sequence-files/IGVFFI4036POXY/",
"/sequence-files/IGVFFI8726ULXT/"
],
"file_format": "tsv",
"file_size": 274,
"href": "/tabular-files/IGVFFI2879FWTA/@@download/IGVFFI2879FWTA.tsv.gz",
"md5sum": "a34575ead12eb26871f1f394fc74a709",
"s3_uri": "s3://igvf-files/2024/12/17/4fded307-2c33-4d31-b9c2-4bf752d84528/IGVFFI2879FWTA.tsv.gz",
"status": "preview",
"submitted_file_name": "PPIF_5PrimeSpliceIndividual_AGGT_TCCA_AllelicEffectsStats.tsv.gz",
"upload_status": "validated"
},
{
"@id": "/tabular-files/IGVFFI2542METL/",
"accession": "IGVFFI2542METL",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1_Variant-EFFECTS_File_Standardized"
],
"assembly": "GRCh38",
"content_type": "variant effects",
"controlled_access": false,
"creation_timestamp": "2025-03-29T00:14:50.662129+00:00",
"derived_from": [
"/tabular-files/IGVFFI2879FWTA/"
],
"file_format": "tsv",
"file_size": 334,
"href": "/tabular-files/IGVFFI2542METL/@@download/IGVFFI2542METL.tsv.gz",
"md5sum": "c996f490603e41df8ad033165b51fddc",
"s3_uri": "s3://igvf-files/2025/03/29/df22e0f1-a478-46e6-b1fe-ec343d9f23b6/IGVFFI2542METL.tsv.gz",
"status": "preview",
"submitted_file_name": "PPIF_5PrimeSpliceIndividual_AGGT_TCCA_VariantEffectsFile.tsv.gz",
"upload_status": "validated"
}
],
"functional_assay_mechanisms": [],
"input_file_sets": [
{
"@id": "/measurement-sets/IGVFDS0861MZYT/",
"accession": "IGVFDS0861MZYT",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSitePool-THP1-PE2_Exp6_NegControl_AmpliconSequencing",
"jesse-engreitz:THP1-PE2_Exp7_PPIF_5SpliceSite-IndividualVariantExp_NegControl_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS3671LLGR/",
"accession": "IGVFDS3671LLGR",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-BinA_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS6675OBBO/",
"accession": "IGVFDS6675OBBO",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-BinB_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS4412KNQI/",
"accession": "IGVFDS4412KNQI",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-BinC_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS7390OIZX/",
"accession": "IGVFDS7390OIZX",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-BinD_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS7859TASD/",
"accession": "IGVFDS7859TASD",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-FACS_Input_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS7911FHLT/",
"accession": "IGVFDS7911FHLT",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-BinA_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS0844IDHW/",
"accession": "IGVFDS0844IDHW",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-BinB_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS2291NKQN/",
"accession": "IGVFDS2291NKQN",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-BinC_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS5840GDYQ/",
"accession": "IGVFDS5840GDYQ",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-BinD_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS1248KTOA/",
"accession": "IGVFDS1248KTOA",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-FACS_Input_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS4959DCXM/",
"accession": "IGVFDS4959DCXM",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-BinA_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS6358OTHG/",
"accession": "IGVFDS6358OTHG",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-BinB_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS0561TMHL/",
"accession": "IGVFDS0561TMHL",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-BinC_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS1533EFZO/",
"accession": "IGVFDS1533EFZO",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-BinD_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS3793UEHT/",
"accession": "IGVFDS3793UEHT",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-FACS_Input_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS1903ZZEJ/",
"accession": "IGVFDS1903ZZEJ",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-BinA_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS1297FZAK/",
"accession": "IGVFDS1297FZAK",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-BinB_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS7310MDWF/",
"accession": "IGVFDS7310MDWF",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-BinC_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS3719UVFK/",
"accession": "IGVFDS3719UVFK",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-BinD_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
},
{
"@id": "/measurement-sets/IGVFDS2821SYCZ/",
"accession": "IGVFDS2821SYCZ",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-FACS_Input_AmpliconSequencing"
],
"file_set_type": "experimental data",
"status": "preview"
}
],
"input_for": [],
"lab": {
"@id": "/labs/jesse-engreitz/",
"title": "Jesse Engreitz, Stanford"
},
"protocols": [
"https://www.protocols.io/view/flowfish-with-primeflow-36wgq3q4olk5/v1"
],
"sample_summary": "Homo sapiens THP-1 cell line, modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, sorted on expression of PPIF",
"samples": [
{
"@id": "/in-vitro-systems/IGVFSM8534GUZK/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM8534GUZK",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-BinD"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 76-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM0545WENW/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM0545WENW",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-BinB"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 26-50% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM3652RJOP/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM3652RJOP",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-BinD"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 76-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM6742ZNSP/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM6742ZNSP",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-BinB"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 26-50% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM4992KIAE/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM4992KIAE",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-BinB"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 26-50% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM9724FSDM/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM9724FSDM",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-BinA"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM8787PPBP/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM8787PPBP",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSitePool-THP1-PE2_Exp6_NegControl"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM0150ACKK/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM0150ACKK",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-BinA"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM4695GCVW/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM4695GCVW",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-FACS_Input"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM4290BVRW/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM4290BVRW",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-BinD"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 76-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM3128BTFC/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM3128BTFC",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-FACS_Input"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM2856TZQU/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM2856TZQU",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-BinB"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 26-50% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM4171EVTF/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM4171EVTF",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-BinA"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM2894EXAV/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM2894EXAV",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-FACS_Input"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM1873QXGA/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM1873QXGA",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep2-BinC"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 51-75% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM9715ABLU/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM9715ABLU",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep1-BinC"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 51-75% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM9921ZLNA/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM9921ZLNA",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-BinD"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 76-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM3818WNVA/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM3818WNVA",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-BinC"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 51-75% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM5123GFPJ/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM5123GFPJ",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep1-FFrep2-BinC"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 51-75% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM4510CGLN/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM4510CGLN",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-BinA"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line (sorting details: FACS bin for 0-25% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
},
{
"@id": "/in-vitro-systems/IGVFSM1529SCAD/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM1529SCAD",
"aliases": [
"jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2-FFrep1-FACS_Input"
],
"classifications": [
"cell line"
],
"institutional_certificates": [],
"modifications": [
{
"@id": "/crispr-modifications/fc6bc0b3-a064-47d0-b95d-a9af14bb1624/",
"modality": "prime editing",
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0001253/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"aliases": [
"igvf:THP-1"
],
"status": "released",
"summary": "THP-1",
"term_name": "THP-1"
}
],
"status": "preview",
"summary": "Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transduced (lentivirus) with a guide library",
"taxa": "Homo sapiens"
}
],
"schema_version": "10",
"status": "preview",
"submitted_by": {
"@id": "/users/f9e7cd82-a407-4a20-89ee-f4dc668b0cbe/",
"title": "Michael Montgomery"
},
"submitted_files_timestamp": "2024-12-17T21:04:05.768697+00:00",
"summary": "CRISPR prime editing Variant-EFFECTS targeting PPIF integrating a guide (sgRNA) library targeting sequence variants in a genomic locus",
"uuid": "6946328b-3a8f-4b1b-b34e-b5af31751d37",
"workflows": [
{
"@id": "/workflows/IGVFWF0099SJHI/",
"accession": "IGVFWF0099SJHI",
"name": "Variant-EFFECTS Pipeline",
"status": "in progress",
"uniform_pipeline": false
}
]
}