{
"@context": "/terms/",
"@id": "/analysis-sets/IGVFDS3159CKGQ/",
"@type": [
"AnalysisSet",
"FileSet",
"Item"
],
"accession": "IGVFDS3159CKGQ",
"aliases": [
"charles-gersbach:analysis-set-crispra-region3-mouse-hl1-targeted-hicar-rep1-cool"
],
"assay_titles": [
"HiCAR"
],
"audit": {
"WARNING": [
{
"category": "missing nucleic acid delivery",
"detail": "In vitro system [IGVFSM3147FFHB](/in-vitro-systems/IGVFSM3147FFHB/) has `construct_library_sets` but is missing `nucleic_acid_delivery`. Samples linked to construct library sets are expected to specify nucleic acid delivery method.",
"level": 40,
"level_name": "WARNING",
"name": "audit_missing_nucleic_acid_delivery",
"path": "/in-vitro-systems/IGVFSM3147FFHB/"
}
]
},
"award": {
"@id": "/awards/HG012053/",
"component": "functional characterization",
"contact_pi": {
"@id": "/users/5d329c0e-3ea9-49bf-9bb9-844a53a882c0/",
"title": "Charles Gersbach"
},
"title": "High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular Phenotypes"
},
"construct_library_sets": [
{
"@id": "/construct-library-sets/IGVFDS8122GWMC/",
"accession": "IGVFDS8122GWMC",
"file_set_type": "guide library",
"integrated_content_files": [
{
"@id": "/tabular-files/IGVFFI7693PBDH/",
"accession": "IGVFFI7693PBDH",
"content_type": "guide RNA sequences",
"status": "released",
"summary": "GRCm39 guide RNA sequences"
}
],
"status": "released",
"summary": "guide (sgRNA) library targeting accessible genome regions in a genomic locus"
}
],
"control_for": [],
"creation_timestamp": "2024-11-07T15:46:53.205385+00:00",
"donors": [
{
"@id": "/rodent-donors/IGVFDO1434JYIN/",
"accession": "IGVFDO1434JYIN",
"aliases": [
"charles-gersbach:mouse-donor-HL-1"
],
"sex": "female",
"status": "released",
"taxa": "Mus musculus"
}
],
"file_set_type": "intermediate analysis",
"files": [
{
"@id": "/matrix-files/IGVFFI9858AGRD/",
"accession": "IGVFFI9858AGRD",
"aliases": [
"charles-gersbach:matrix-file-crispra-region3-mouse-hl1-targeted-hicar-rep1-mcool"
],
"content_type": "contact matrix",
"creation_timestamp": "2024-11-07T16:07:35.155942+00:00",
"file_format": "mcool",
"file_size": 50899390,
"href": "/matrix-files/IGVFFI9858AGRD/@@download/IGVFFI9858AGRD.mcool",
"s3_uri": "s3://igvf-files/2024/11/07/176d7d58-9f57-4532-b73a-e06fc3fa7d2a/IGVFFI9858AGRD.mcool",
"status": "released",
"submitted_file_name": "/hpc/group/gersbachlab/tda17/IGVF_data_files/HiCAR/output/cooler/mouse/HL1_TA446_CA_1_ctrl.1000.mcool",
"upload_status": "validated"
},
{
"@id": "/matrix-files/IGVFFI4340DYQT/",
"accession": "IGVFFI4340DYQT",
"aliases": [
"charles-gersbach:matrix-file-crispra-region3-mouse-hl1-targeted-hicar-rep1-cool"
],
"content_type": "contact matrix",
"creation_timestamp": "2024-11-07T16:07:33.350360+00:00",
"file_format": "cool",
"file_size": 11295842,
"href": "/matrix-files/IGVFFI4340DYQT/@@download/IGVFFI4340DYQT.cool",
"s3_uri": "s3://igvf-files/2024/11/07/0a0b1c64-aa0c-475f-9ed2-a9b690a3636e/IGVFFI4340DYQT.cool",
"status": "released",
"submitted_file_name": "/hpc/group/gersbachlab/tda17/IGVF_data_files/HiCAR/output/cooler/mouse/HL1_TA446_CA_1_ctrl.1000.cool",
"upload_status": "validated"
}
],
"functional_assay_mechanisms": [],
"input_file_sets": [
{
"@id": "/measurement-sets/IGVFDS7037REPR/",
"accession": "IGVFDS7037REPR",
"aliases": [
"charles-gersbach:measurement-set-crispra-region3-mouse-hl1-targeted-hicar-rep1"
],
"file_set_type": "experimental data",
"status": "released"
}
],
"input_for": [
"/analysis-sets/IGVFDS0872LUHP/"
],
"lab": {
"@id": "/labs/charles-gersbach/",
"title": "Charles Gersbach, Duke"
},
"protocols": [
"https://www.protocols.io/view/hicar-for-mouse-hl-1-cells-following-enhancer-pert-36wgqn2yygk5"
],
"release_timestamp": "2024-12-13T19:43:28.509467+00:00",
"sample_summary": "HL-1 cell line, transfected with a guide library",
"samples": [
{
"@id": "/in-vitro-systems/IGVFSM3147FFHB/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM3147FFHB",
"aliases": [
"charles-gersbach:in-vitro-system-crispra-region3-mouse-hl1-targeted-hicar-rep1"
],
"classifications": [
"cell line"
],
"institutional_certificates": [
{
"@id": "/institutional-certificates/a62cea9b-2ae0-44e8-a6d6-81f419c56c71/",
"certificate_identifier": "IP117-03",
"controlled_access": false,
"status": "released"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0022835/",
"@type": [
"SampleTerm",
"OntologyTerm",
"Item"
],
"status": "released",
"summary": "HL-1",
"term_name": "HL-1"
}
],
"status": "released",
"summary": "HL-1 cell line, female, Mus musculus C57BL/6J transfected with a guide library",
"taxa": "Mus musculus"
}
],
"schema_version": "9",
"status": "released",
"submitted_by": {
"@id": "/users/3782ce69-0e9f-4b46-91f9-4578139785c7/",
"title": "Ruhi Rai"
},
"submitted_files_timestamp": "2024-11-07T16:07:33.350360+00:00",
"summary": "HiCAR: contact matrix",
"uuid": "e49c7bc7-f2bb-4804-9686-67d7cba547e1",
"workflows": [
{
"@id": "/workflows/IGVFWF1709OHTV/",
"accession": "IGVFWF1709OHTV",
"name": "nf-core HiCAR Pipeline",
"status": "released",
"uniform_pipeline": false
}
]
}