IGVFDS2302NLIO

released
{
    "@context": "/terms/",
    "@id": "/analysis-sets/IGVFDS2302NLIO/",
    "@type": [
        "AnalysisSet",
        "FileSet",
        "Item"
    ],
    "accession": "IGVFDS2302NLIO",
    "aliases": [
        "charles-gersbach:cd8-tcells-analysis-set-atac-seq-acute-activation-batf3"
    ],
    "assay_titles": [
        "ATAC-seq"
    ],
    "audit": {
        "INTERNAL_ACTION": [
            {
                "category": "mismatched status",
                "detail": "Released primary cell [IGVFSM4716FORO](/primary-cells/IGVFSM4716FORO/) has in progress subobject treatment [725c21b1-d202-4a6c-89a4-e4fc05a001e8](/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/primary-cells/IGVFSM4716FORO/"
            },
            {
                "category": "mismatched status",
                "detail": "Released primary cell [IGVFSM8800PZZL](/primary-cells/IGVFSM8800PZZL/) has in progress subobject treatment [725c21b1-d202-4a6c-89a4-e4fc05a001e8](/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/primary-cells/IGVFSM8800PZZL/"
            },
            {
                "category": "mismatched status",
                "detail": "Released primary cell [IGVFSM0066TACG](/primary-cells/IGVFSM0066TACG/) has in progress subobject treatment [725c21b1-d202-4a6c-89a4-e4fc05a001e8](/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/primary-cells/IGVFSM0066TACG/"
            },
            {
                "category": "mismatched status",
                "detail": "Released primary cell [IGVFSM0293OVAT](/primary-cells/IGVFSM0293OVAT/) has in progress subobject treatment [725c21b1-d202-4a6c-89a4-e4fc05a001e8](/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/primary-cells/IGVFSM0293OVAT/"
            },
            {
                "category": "NTR term ID",
                "detail": "Treatment term for [725c21b1-d202-4a6c-89a4-e4fc05a001e8](/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/) has been newly requested. Treatments with a newly requested term ID are expected to have it updated following its addition to the appropriate ontology database.",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_treatment_term_id_check",
                "path": "/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/"
            },
            {
                "category": "mismatched status",
                "detail": "Released primary cell [IGVFSM3998OQDA](/primary-cells/IGVFSM3998OQDA/) has in progress subobject treatment [725c21b1-d202-4a6c-89a4-e4fc05a001e8](/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/primary-cells/IGVFSM3998OQDA/"
            },
            {
                "category": "mismatched status",
                "detail": "Released primary cell [IGVFSM6851CRLW](/primary-cells/IGVFSM6851CRLW/) has in progress subobject treatment [725c21b1-d202-4a6c-89a4-e4fc05a001e8](/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/primary-cells/IGVFSM6851CRLW/"
            }
        ],
        "WARNING": [
            {
                "category": "missing age",
                "detail": "Primary cell [IGVFSM4716FORO](/primary-cells/IGVFSM4716FORO/) is missing `upper_bound_age`, `lower_bound_age`, and `age_units`. Tissues, primary cells, and whole organisms are expected to specify a lower bound age, upper bound age, and age units.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_biosample_age",
                "path": "/primary-cells/IGVFSM4716FORO/"
            },
            {
                "category": "missing age",
                "detail": "Primary cell [IGVFSM8800PZZL](/primary-cells/IGVFSM8800PZZL/) is missing `upper_bound_age`, `lower_bound_age`, and `age_units`. Tissues, primary cells, and whole organisms are expected to specify a lower bound age, upper bound age, and age units.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_biosample_age",
                "path": "/primary-cells/IGVFSM8800PZZL/"
            },
            {
                "category": "missing age",
                "detail": "Primary cell [IGVFSM0066TACG](/primary-cells/IGVFSM0066TACG/) is missing `upper_bound_age`, `lower_bound_age`, and `age_units`. Tissues, primary cells, and whole organisms are expected to specify a lower bound age, upper bound age, and age units.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_biosample_age",
                "path": "/primary-cells/IGVFSM0066TACG/"
            },
            {
                "category": "missing age",
                "detail": "Primary cell [IGVFSM0293OVAT](/primary-cells/IGVFSM0293OVAT/) is missing `upper_bound_age`, `lower_bound_age`, and `age_units`. Tissues, primary cells, and whole organisms are expected to specify a lower bound age, upper bound age, and age units.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_biosample_age",
                "path": "/primary-cells/IGVFSM0293OVAT/"
            },
            {
                "category": "missing age",
                "detail": "Primary cell [IGVFSM3998OQDA](/primary-cells/IGVFSM3998OQDA/) is missing `upper_bound_age`, `lower_bound_age`, and `age_units`. Tissues, primary cells, and whole organisms are expected to specify a lower bound age, upper bound age, and age units.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_biosample_age",
                "path": "/primary-cells/IGVFSM3998OQDA/"
            },
            {
                "category": "missing age",
                "detail": "Primary cell [IGVFSM6851CRLW](/primary-cells/IGVFSM6851CRLW/) is missing `upper_bound_age`, `lower_bound_age`, and `age_units`. Tissues, primary cells, and whole organisms are expected to specify a lower bound age, upper bound age, and age units.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_biosample_age",
                "path": "/primary-cells/IGVFSM6851CRLW/"
            }
        ]
    },
    "award": {
        "@id": "/awards/HG012053/",
        "component": "functional characterization",
        "contact_pi": {
            "@id": "/users/5d329c0e-3ea9-49bf-9bb9-844a53a882c0/",
            "title": "Charles Gersbach"
        },
        "title": "High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular Phenotypes"
    },
    "construct_library_sets": [
        {
            "@id": "/construct-library-sets/IGVFDS5584SPIV/",
            "accession": "IGVFDS5584SPIV",
            "file_set_type": "expression vector library",
            "status": "released",
            "summary": "control transduction expression vector library"
        },
        {
            "@id": "/construct-library-sets/IGVFDS1868WXHB/",
            "accession": "IGVFDS1868WXHB",
            "file_set_type": "expression vector library",
            "status": "released",
            "summary": "expression vector library of BATF3"
        }
    ],
    "control_for": [],
    "controlled_access": false,
    "creation_timestamp": "2024-08-30T18:03:11.676153+00:00",
    "data_use_limitation_summaries": [
        "No limitations"
    ],
    "donors": [
        {
            "@id": "/human-donors/IGVFDO1522NSLA/",
            "accession": "IGVFDO1522NSLA",
            "aliases": [
                "charles-gersbach:cd8-tcells-donor-10"
            ],
            "sex": "unspecified",
            "status": "released",
            "taxa": "Homo sapiens"
        },
        {
            "@id": "/human-donors/IGVFDO8289ZMDD/",
            "accession": "IGVFDO8289ZMDD",
            "aliases": [
                "charles-gersbach:cd8-tcells-donor-11"
            ],
            "sex": "unspecified",
            "status": "released",
            "taxa": "Homo sapiens"
        },
        {
            "@id": "/human-donors/IGVFDO9588OERW/",
            "accession": "IGVFDO9588OERW",
            "aliases": [
                "charles-gersbach:cd8-tcells-donor-9"
            ],
            "sex": "unspecified",
            "status": "released",
            "taxa": "Homo sapiens"
        }
    ],
    "file_set_type": "principal analysis",
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            "accession": "IGVFFI2320OTYL",
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                "charles-gersbach:cd8-tcells-deseq2-results-atac-seq-acute-activation"
            ],
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            "content_type": "fold change over control",
            "controlled_access": false,
            "creation_timestamp": "2024-09-05T20:42:48.546501+00:00",
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            "status": "released",
            "submitted_file_name": "/data/reddylab/Alex/IGVF/data_submissions/processed_data/AIM_2_T_cell_project_1/DESeq2.BATF3.vs.control.chronic.simple.txt.gz",
            "upload_status": "validated"
        },
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            "@id": "/tabular-files/IGVFFI4701TPMH/",
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            "content_type": "peak quantifications",
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            "creation_timestamp": "2024-09-20T18:53:48.515093+00:00",
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            "upload_status": "validated"
        },
        {
            "@id": "/alignment-files/IGVFFI2179DDWP/",
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            "upload_status": "validated"
        },
        {
            "@id": "/alignment-files/IGVFFI1726ZIZH/",
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            "submitted_file_name": "/data/reddylab/Alex/IGVF/data_submissions/processed_data/AIM_2_T_cell_project_1/SCM-69-rep1.masked.dups_marked.bam",
            "upload_status": "validated"
        },
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            "@id": "/alignment-files/IGVFFI6004VZDI/",
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            "upload_status": "validated"
        },
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            "@id": "/alignment-files/IGVFFI2447WIHU/",
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            "upload_status": "validated"
        },
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            "@id": "/alignment-files/IGVFFI3376UGYD/",
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            "assembly": "GRCh38",
            "content_type": "alignments",
            "controlled_access": false,
            "creation_timestamp": "2024-10-14T21:14:54.405281+00:00",
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            "upload_status": "validated"
        },
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            "@id": "/alignment-files/IGVFFI1198PNDA/",
            "accession": "IGVFFI1198PNDA",
            "aliases": [
                "charles-gersbach:cd8-tcells-atac-seq-acute-activation-batf3-bam-rep2"
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            "assembly": "GRCh38",
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            "upload_status": "validated"
        }
    ],
    "functional_assay_mechanisms": [],
    "input_file_sets": [
        {
            "@id": "/measurement-sets/IGVFDS7967GRIT/",
            "accession": "IGVFDS7967GRIT",
            "aliases": [
                "charles-gersbach:cd8-tcells-atac-seq-acute-activation-gfp-rep1"
            ],
            "file_set_type": "experimental data",
            "status": "released"
        },
        {
            "@id": "/measurement-sets/IGVFDS5416ROJO/",
            "accession": "IGVFDS5416ROJO",
            "aliases": [
                "charles-gersbach:cd8-tcells-atac-seq-acute-activation-gfp-rep2"
            ],
            "file_set_type": "experimental data",
            "status": "released"
        },
        {
            "@id": "/measurement-sets/IGVFDS5049UPEO/",
            "accession": "IGVFDS5049UPEO",
            "aliases": [
                "charles-gersbach:cd8-tcells-atac-seq-acute-activation-gfp-rep3"
            ],
            "file_set_type": "experimental data",
            "status": "released"
        },
        {
            "@id": "/measurement-sets/IGVFDS1619VKNB/",
            "accession": "IGVFDS1619VKNB",
            "aliases": [
                "charles-gersbach:cd8-tcells-atac-seq-acute-activation-batf3-rep1"
            ],
            "file_set_type": "experimental data",
            "status": "released"
        },
        {
            "@id": "/measurement-sets/IGVFDS2737CQNK/",
            "accession": "IGVFDS2737CQNK",
            "aliases": [
                "charles-gersbach:cd8-tcells-atac-seq-acute-activation-batf3-rep2"
            ],
            "file_set_type": "experimental data",
            "status": "released"
        },
        {
            "@id": "/measurement-sets/IGVFDS5292QYYE/",
            "accession": "IGVFDS5292QYYE",
            "aliases": [
                "charles-gersbach:cd8-tcells-atac-seq-acute-activation-batf3-rep3"
            ],
            "file_set_type": "experimental data",
            "status": "released"
        }
    ],
    "input_for": [],
    "lab": {
        "@id": "/labs/charles-gersbach/",
        "title": "Charles Gersbach, Duke"
    },
    "protocols": [
        "https://www.protocols.io/view/atac-seq-primary-human-t-cells-overexpressing-batf-c5pfy5jn"
    ],
    "publications": [
        {
            "@id": "/publications/6cc80a53-4ca1-4bd4-9942-f0f335b7ec20/",
            "publication_identifiers": [
                "PMID:37945901",
                "doi:10.1038/s41588-023-01554-0",
                "PMCID:PMC10703699"
            ],
            "status": "released"
        }
    ],
    "release_timestamp": "2024-10-29T17:33:34.389360+00:00",
    "sample_summary": "Homo sapiens CD8-positive, alpha-beta memory T primary cell primary cell, stimulated with 300 percent Antibody Coated Bead, transfected with a expression vector library",
    "samples": [
        {
            "@id": "/primary-cells/IGVFSM0293OVAT/",
            "@type": [
                "PrimaryCell",
                "Biosample",
                "Sample",
                "Item"
            ],
            "accession": "IGVFSM0293OVAT",
            "aliases": [
                "charles-gersbach:cd8-tcells-primary-cell-acute-activation-batf3-rep3"
            ],
            "classifications": [
                "primary cell"
            ],
            "institutional_certificates": [
                {
                    "@id": "/institutional-certificates/e1533003-0a58-47b1-aa1a-615dbb6aafb2/",
                    "certificate_identifier": "IP117-01",
                    "controlled_access": false,
                    "status": "released"
                }
            ],
            "sample_terms": [
                {
                    "@id": "/sample-terms/CL_0000909/",
                    "@type": [
                        "SampleTerm",
                        "OntologyTerm",
                        "Item"
                    ],
                    "status": "released",
                    "summary": "CD8-positive, alpha-beta memory T cell",
                    "term_name": "CD8-positive, alpha-beta memory T cell"
                }
            ],
            "status": "released",
            "summary": "Homo sapiens CD8-positive, alpha-beta memory T cell treated with 300 percent Antibody Coated Bead, transduced (lentivirus) with a expression vector library",
            "taxa": "Homo sapiens",
            "treatments": [
                {
                    "@id": "/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/",
                    "purpose": "stimulation",
                    "status": "in progress",
                    "summary": "Treatment of 300 percent Antibody Coated Bead",
                    "treatment_type": "protein"
                }
            ]
        },
        {
            "@id": "/primary-cells/IGVFSM0066TACG/",
            "@type": [
                "PrimaryCell",
                "Biosample",
                "Sample",
                "Item"
            ],
            "accession": "IGVFSM0066TACG",
            "aliases": [
                "charles-gersbach:cd8-tcells-primary-cell-acute-activation-batf3-rep1"
            ],
            "classifications": [
                "primary cell"
            ],
            "institutional_certificates": [
                {
                    "@id": "/institutional-certificates/e1533003-0a58-47b1-aa1a-615dbb6aafb2/",
                    "certificate_identifier": "IP117-01",
                    "controlled_access": false,
                    "status": "released"
                }
            ],
            "sample_terms": [
                {
                    "@id": "/sample-terms/CL_0000909/",
                    "@type": [
                        "SampleTerm",
                        "OntologyTerm",
                        "Item"
                    ],
                    "status": "released",
                    "summary": "CD8-positive, alpha-beta memory T cell",
                    "term_name": "CD8-positive, alpha-beta memory T cell"
                }
            ],
            "status": "released",
            "summary": "Homo sapiens CD8-positive, alpha-beta memory T cell treated with 300 percent Antibody Coated Bead, transduced (lentivirus) with a expression vector library",
            "taxa": "Homo sapiens",
            "treatments": [
                {
                    "@id": "/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/",
                    "purpose": "stimulation",
                    "status": "in progress",
                    "summary": "Treatment of 300 percent Antibody Coated Bead",
                    "treatment_type": "protein"
                }
            ]
        },
        {
            "@id": "/primary-cells/IGVFSM6851CRLW/",
            "@type": [
                "PrimaryCell",
                "Biosample",
                "Sample",
                "Item"
            ],
            "accession": "IGVFSM6851CRLW",
            "aliases": [
                "charles-gersbach:cd8-tcells-primary-cell-acute-activation-gfp-rep2"
            ],
            "classifications": [
                "primary cell"
            ],
            "institutional_certificates": [
                {
                    "@id": "/institutional-certificates/e1533003-0a58-47b1-aa1a-615dbb6aafb2/",
                    "certificate_identifier": "IP117-01",
                    "controlled_access": false,
                    "status": "released"
                }
            ],
            "sample_terms": [
                {
                    "@id": "/sample-terms/CL_0000909/",
                    "@type": [
                        "SampleTerm",
                        "OntologyTerm",
                        "Item"
                    ],
                    "status": "released",
                    "summary": "CD8-positive, alpha-beta memory T cell",
                    "term_name": "CD8-positive, alpha-beta memory T cell"
                }
            ],
            "status": "released",
            "summary": "Homo sapiens CD8-positive, alpha-beta memory T cell treated with 300 percent Antibody Coated Bead, transduced (lentivirus) with a expression vector library",
            "taxa": "Homo sapiens",
            "treatments": [
                {
                    "@id": "/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/",
                    "purpose": "stimulation",
                    "status": "in progress",
                    "summary": "Treatment of 300 percent Antibody Coated Bead",
                    "treatment_type": "protein"
                }
            ]
        },
        {
            "@id": "/primary-cells/IGVFSM3998OQDA/",
            "@type": [
                "PrimaryCell",
                "Biosample",
                "Sample",
                "Item"
            ],
            "accession": "IGVFSM3998OQDA",
            "aliases": [
                "charles-gersbach:cd8-tcells-primary-cell-acute-activation-gfp-rep1"
            ],
            "classifications": [
                "primary cell"
            ],
            "institutional_certificates": [
                {
                    "@id": "/institutional-certificates/e1533003-0a58-47b1-aa1a-615dbb6aafb2/",
                    "certificate_identifier": "IP117-01",
                    "controlled_access": false,
                    "status": "released"
                }
            ],
            "sample_terms": [
                {
                    "@id": "/sample-terms/CL_0000909/",
                    "@type": [
                        "SampleTerm",
                        "OntologyTerm",
                        "Item"
                    ],
                    "status": "released",
                    "summary": "CD8-positive, alpha-beta memory T cell",
                    "term_name": "CD8-positive, alpha-beta memory T cell"
                }
            ],
            "status": "released",
            "summary": "Homo sapiens CD8-positive, alpha-beta memory T cell treated with 300 percent Antibody Coated Bead, transduced (lentivirus) with a expression vector library",
            "taxa": "Homo sapiens",
            "treatments": [
                {
                    "@id": "/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/",
                    "purpose": "stimulation",
                    "status": "in progress",
                    "summary": "Treatment of 300 percent Antibody Coated Bead",
                    "treatment_type": "protein"
                }
            ]
        },
        {
            "@id": "/primary-cells/IGVFSM8800PZZL/",
            "@type": [
                "PrimaryCell",
                "Biosample",
                "Sample",
                "Item"
            ],
            "accession": "IGVFSM8800PZZL",
            "aliases": [
                "charles-gersbach:cd8-tcells-primary-cell-acute-activation-gfp-rep3"
            ],
            "classifications": [
                "primary cell"
            ],
            "institutional_certificates": [
                {
                    "@id": "/institutional-certificates/e1533003-0a58-47b1-aa1a-615dbb6aafb2/",
                    "certificate_identifier": "IP117-01",
                    "controlled_access": false,
                    "status": "released"
                }
            ],
            "sample_terms": [
                {
                    "@id": "/sample-terms/CL_0000909/",
                    "@type": [
                        "SampleTerm",
                        "OntologyTerm",
                        "Item"
                    ],
                    "status": "released",
                    "summary": "CD8-positive, alpha-beta memory T cell",
                    "term_name": "CD8-positive, alpha-beta memory T cell"
                }
            ],
            "status": "released",
            "summary": "Homo sapiens CD8-positive, alpha-beta memory T cell treated with 300 percent Antibody Coated Bead, transduced (lentivirus) with a expression vector library",
            "taxa": "Homo sapiens",
            "treatments": [
                {
                    "@id": "/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/",
                    "purpose": "stimulation",
                    "status": "in progress",
                    "summary": "Treatment of 300 percent Antibody Coated Bead",
                    "treatment_type": "protein"
                }
            ]
        },
        {
            "@id": "/primary-cells/IGVFSM4716FORO/",
            "@type": [
                "PrimaryCell",
                "Biosample",
                "Sample",
                "Item"
            ],
            "accession": "IGVFSM4716FORO",
            "aliases": [
                "charles-gersbach:cd8-tcells-primary-cell-acute-activation-batf3-rep2"
            ],
            "classifications": [
                "primary cell"
            ],
            "institutional_certificates": [
                {
                    "@id": "/institutional-certificates/e1533003-0a58-47b1-aa1a-615dbb6aafb2/",
                    "certificate_identifier": "IP117-01",
                    "controlled_access": false,
                    "status": "released"
                }
            ],
            "sample_terms": [
                {
                    "@id": "/sample-terms/CL_0000909/",
                    "@type": [
                        "SampleTerm",
                        "OntologyTerm",
                        "Item"
                    ],
                    "status": "released",
                    "summary": "CD8-positive, alpha-beta memory T cell",
                    "term_name": "CD8-positive, alpha-beta memory T cell"
                }
            ],
            "status": "released",
            "summary": "Homo sapiens CD8-positive, alpha-beta memory T cell treated with 300 percent Antibody Coated Bead, transduced (lentivirus) with a expression vector library",
            "taxa": "Homo sapiens",
            "treatments": [
                {
                    "@id": "/treatments/725c21b1-d202-4a6c-89a4-e4fc05a001e8/",
                    "purpose": "stimulation",
                    "status": "in progress",
                    "summary": "Treatment of 300 percent Antibody Coated Bead",
                    "treatment_type": "protein"
                }
            ]
        }
    ],
    "schema_version": "9",
    "status": "released",
    "submitted_by": {
        "@id": "/users/29f5f78d-ac90-421e-90c6-a90e1dc407a7/",
        "title": "Alejandro Barrera"
    },
    "submitted_files_timestamp": "2024-09-05T20:42:48.546501+00:00",
    "summary": "ATAC-seq: alignments, fold change over control, peak quantifications",
    "uuid": "dddf113e-e357-4ec4-bb4f-ab705219db19",
    "workflows": [
        {
            "@id": "/workflows/IGVFWF6411VZLF/",
            "accession": "IGVFWF6411VZLF",
            "name": "Gersbach GGR ATAC-seq Pipeline",
            "status": "released"
        }
    ]
}