substantia nigra — IGVFSM1248IPGG

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Summary

Homo sapiens (female, 82 years) substantia nigra tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy, multiple sclerosis

Sample Terms

substantia nigra

Sex

female

Age

82 years

Disease Terms

Alzheimer disease

Post-mortem Interval

135 minutes

Preservation Method

flash-freezing

Taxa

Homo sapiens

Sources

Date Harvested

March 7, 2023

Aliases

igvf:corces_tissue_BANN0437_SN

Protocols

https://www.protocols.io/view/isolation-of-nuclei-from-frozen-tissue-for-snmulti-6uchesw

Donors

1 item

Accession

Aliases

Sex

Taxa

igvf:corces_donor_BANN0437

female

Homo sapiens

File Sets

16 items

single-nucleus RNA sequencing assay (10x multiome)

igvf:corces_measurementSet_X041_G8_RNA

Ryan Corces, Gladstone Institute UCSF

single-nucleus RNA sequencing assay (10x multiome)

igvf:corces_measurementSet_X041_G1_RNA

Ryan Corces, Gladstone Institute UCSF

single-nucleus RNA sequencing assay (10x multiome)

igvf:corces_measurementSet_X041_G5_RNA

Ryan Corces, Gladstone Institute UCSF

single-nucleus ATAC-seq (10x multiome)

igvf:corces_measurementSet_X041_G1_ATAC

Ryan Corces, Gladstone Institute UCSF

single-nucleus RNA sequencing assay (10x multiome)

igvf:corces_measurementSet_X041_G7_RNA

Ryan Corces, Gladstone Institute UCSF

single-nucleus ATAC-seq (10x multiome)

igvf:corces_measurementSet_X041_G7_ATAC

Ryan Corces, Gladstone Institute UCSF

single-nucleus RNA sequencing assay (10x multiome)

igvf:corces_measurementSet_X041_G6_RNA

Ryan Corces, Gladstone Institute UCSF

single-nucleus ATAC-seq (10x multiome)

igvf:corces_measurementSet_X041_G2_ATAC

Ryan Corces, Gladstone Institute UCSF

single-nucleus ATAC-seq (10x multiome)

igvf:corces_measurementSet_X041_G5_ATAC

Ryan Corces, Gladstone Institute UCSF

single-nucleus ATAC-seq (10x multiome)

igvf:corces_measurementSet_X041_G6_ATAC

Ryan Corces, Gladstone Institute UCSF

Multiplexed In Samples

8 items

Sample Terms

Disease Terms

Summary

MultiplexedSample

cerebellar cortex, middle temporal gyrus, posterior cingulate gyrus, putamen, substantia nigra

Alzheimer disease, cerebral amyloid angiopathy, mild cognitive impairment, multiple sclerosis, Parkinson's disease

multiplexed sample: Homo sapiens (male, 72 years) middle temporal gyrus tissue associated with cerebral amyloid angiopathy; Homo sapiens (female, 82 years) substantia nigra tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy, multiple sclerosis; ... and 10 more samples

MultiplexedSample

cerebellar cortex, middle temporal gyrus, posterior cingulate gyrus, putamen, substantia nigra

Alzheimer disease, cerebral amyloid angiopathy, mild cognitive impairment, multiple sclerosis, Parkinson's disease

multiplexed sample: Homo sapiens (male, 72 years) middle temporal gyrus tissue associated with cerebral amyloid angiopathy; Homo sapiens (female, 82 years) substantia nigra tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy, multiple sclerosis; ... and 10 more samples

MultiplexedSample

cerebellar cortex, middle temporal gyrus, posterior cingulate gyrus, putamen, substantia nigra

Alzheimer disease, cerebral amyloid angiopathy, mild cognitive impairment, multiple sclerosis, Parkinson's disease

multiplexed sample: Homo sapiens (male, 72 years) middle temporal gyrus tissue associated with cerebral amyloid angiopathy; Homo sapiens (female, 82 years) substantia nigra tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy, multiple sclerosis; ... and 10 more samples

MultiplexedSample

cerebellar cortex, middle temporal gyrus, posterior cingulate gyrus, putamen, substantia nigra

Alzheimer disease, cerebral amyloid angiopathy, mild cognitive impairment, multiple sclerosis, Parkinson's disease

multiplexed sample: Homo sapiens (male, 72 years) middle temporal gyrus tissue associated with cerebral amyloid angiopathy; Homo sapiens (female, 82 years) substantia nigra tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy, multiple sclerosis; ... and 10 more samples

MultiplexedSample

cerebellar cortex, middle temporal gyrus, posterior cingulate gyrus, putamen, substantia nigra

Alzheimer disease, cerebral amyloid angiopathy, mild cognitive impairment, multiple sclerosis, Parkinson's disease

multiplexed sample: Homo sapiens (male, 72 years) middle temporal gyrus tissue associated with cerebral amyloid angiopathy; Homo sapiens (female, 82 years) substantia nigra tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy, multiple sclerosis; ... and 10 more samples

MultiplexedSample

cerebellar cortex, middle temporal gyrus, posterior cingulate gyrus, putamen, substantia nigra

Alzheimer disease, cerebral amyloid angiopathy, mild cognitive impairment, multiple sclerosis, Parkinson's disease

multiplexed sample: Homo sapiens (male, 72 years) middle temporal gyrus tissue associated with cerebral amyloid angiopathy; Homo sapiens (female, 82 years) substantia nigra tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy, multiple sclerosis; ... and 10 more samples

MultiplexedSample

cerebellar cortex, middle temporal gyrus, posterior cingulate gyrus, putamen, substantia nigra

Alzheimer disease, cerebral amyloid angiopathy, mild cognitive impairment, multiple sclerosis, Parkinson's disease

multiplexed sample: Homo sapiens (male, 72 years) middle temporal gyrus tissue associated with cerebral amyloid angiopathy; Homo sapiens (female, 82 years) substantia nigra tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy, multiple sclerosis; ... and 10 more samples

MultiplexedSample

cerebellar cortex, middle temporal gyrus, posterior cingulate gyrus, putamen, substantia nigra

Alzheimer disease, cerebral amyloid angiopathy, mild cognitive impairment, multiple sclerosis, Parkinson's disease

multiplexed sample: Homo sapiens (male, 72 years) middle temporal gyrus tissue associated with cerebral amyloid angiopathy; Homo sapiens (female, 82 years) substantia nigra tissue associated with Alzheimer disease, Parkinson's disease, cerebral amyloid angiopathy, multiple sclerosis; ... and 10 more samples

Attribution

Award

Principal Investigator(s)

Ansuman Satpathy

Contact P.I.

Ansuman Satpathy

Lab

Ryan Corces, Gladstone Institute UCSF