substantia nigra — IGVFSM0203GIXJ

{
    "@context": "/terms/",
    "@id": "/tissues/IGVFSM0203GIXJ/",
    "@type": [
        "Tissue",
        "Biosample",
        "Sample",
        "Item"
    ],
    "accession": "IGVFSM0203GIXJ",
    "age": "87",
    "age_units": "year",
    "aliases": [
        "igvf:corces_tissue_BANN1851_SN"
    ],
    "audit": {
        "INTERNAL_ACTION": [
            {
                "category": "mismatched status",
                "detail": "Preview tissue [IGVFSM0203GIXJ](/tissues/IGVFSM0203GIXJ/) has in progress subobject phenotype term [DOID_9246](/phenotype-terms/DOID_9246/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/tissues/IGVFSM0203GIXJ/"
            },
            {
                "category": "mismatched status",
                "detail": "Preview tissue [IGVFSM0203GIXJ](/tissues/IGVFSM0203GIXJ/) has in progress subobject phenotype term [DOID_14330](/phenotype-terms/DOID_14330/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/tissues/IGVFSM0203GIXJ/"
            },
            {
                "category": "missing CCF ID",
                "detail": "Tissue [IGVFSM0203GIXJ](/tissues/IGVFSM0203GIXJ/) is missing a `ccf_id`. Human tissues are expected to specify a common coordinate framework identifier (CCF ID).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_tissue_ccf_id",
                "path": "/tissues/IGVFSM0203GIXJ/"
            }
        ]
    },
    "award": {
        "@id": "/awards/HG012076/",
        "component": "mapping"
    },
    "classifications": [
        "tissue"
    ],
    "creation_timestamp": "2025-03-19T04:10:22.782633+00:00",
    "date_obtained": "2022-11-29",
    "disease_terms": [
        {
            "@id": "/phenotype-terms/DOID_14330/",
            "status": "in progress",
            "term_name": "Parkinson's disease"
        },
        {
            "@id": "/phenotype-terms/DOID_9246/",
            "status": "in progress",
            "term_name": "cerebral amyloid angiopathy"
        }
    ],
    "donors": [
        {
            "@id": "/human-donors/IGVFDO1052TZWO/",
            "accession": "IGVFDO1052TZWO",
            "ethnicities": [
                "European"
            ],
            "status": "preview"
        }
    ],
    "file_sets": [
        {
            "@id": "/measurement-sets/IGVFDS5254MWSY/",
            "accession": "IGVFDS5254MWSY",
            "aliases": [
                "igvf:corces_measurementSet_X019_G2_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS5680MIKN/",
            "accession": "IGVFDS5680MIKN",
            "aliases": [
                "igvf:corces_measurementSet_X019_G2_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS6875UIRT/",
            "accession": "IGVFDS6875UIRT",
            "aliases": [
                "igvf:corces_measurementSet_X019_G3_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS9444FAGC/",
            "accession": "IGVFDS9444FAGC",
            "aliases": [
                "igvf:corces_measurementSet_X019_G3_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS4972YWYE/",
            "accession": "IGVFDS4972YWYE",
            "aliases": [
                "igvf:corces_measurementSet_X019_G1_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS4277JFOH/",
            "accession": "IGVFDS4277JFOH",
            "aliases": [
                "igvf:corces_measurementSet_X019_G1_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS6520VCSN/",
            "accession": "IGVFDS6520VCSN",
            "aliases": [
                "igvf:corces_measurementSet_X019_G6_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS0924SKZZ/",
            "accession": "IGVFDS0924SKZZ",
            "aliases": [
                "igvf:corces_measurementSet_X019_G6_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS6772MGFV/",
            "accession": "IGVFDS6772MGFV",
            "aliases": [
                "igvf:corces_measurementSet_X019_G5_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS9363KBSZ/",
            "accession": "IGVFDS9363KBSZ",
            "aliases": [
                "igvf:corces_measurementSet_X019_G5_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS9294SIEC/",
            "accession": "IGVFDS9294SIEC",
            "aliases": [
                "igvf:corces_measurementSet_X019_G7_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS2306FJYZ/",
            "accession": "IGVFDS2306FJYZ",
            "aliases": [
                "igvf:corces_measurementSet_X019_G7_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS1812PDJF/",
            "accession": "IGVFDS1812PDJF",
            "aliases": [
                "igvf:corces_measurementSet_X019_G8_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS2043CBXG/",
            "accession": "IGVFDS2043CBXG",
            "aliases": [
                "igvf:corces_measurementSet_X019_G8_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS6736LYRQ/",
            "accession": "IGVFDS6736LYRQ",
            "aliases": [
                "igvf:corces_measurementSet_X019_G4_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS1525DIBQ/",
            "accession": "IGVFDS1525DIBQ",
            "aliases": [
                "igvf:corces_measurementSet_X019_G4_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS6778JTHZ/",
            "accession": "IGVFDS6778JTHZ",
            "aliases": [
                "igvf:corces_measurementSet_RP017_G4_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS5441GNGR/",
            "accession": "IGVFDS5441GNGR",
            "aliases": [
                "igvf:corces_measurementSet_RP017_G4_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS6703RFLO/",
            "accession": "IGVFDS6703RFLO",
            "aliases": [
                "igvf:corces_measurementSet_RP017_G1_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS3632OOWJ/",
            "accession": "IGVFDS3632OOWJ",
            "aliases": [
                "igvf:corces_measurementSet_RP017_G1_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS3192IDFV/",
            "accession": "IGVFDS3192IDFV",
            "aliases": [
                "igvf:corces_measurementSet_RP017_G2_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS6469UTWA/",
            "accession": "IGVFDS6469UTWA",
            "aliases": [
                "igvf:corces_measurementSet_RP017_G2_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS9366EKYM/",
            "accession": "IGVFDS9366EKYM",
            "aliases": [
                "igvf:corces_measurementSet_RP017_G3_ATAC"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus ATAC-seq (10x multiome)"
        },
        {
            "@id": "/measurement-sets/IGVFDS9780HOAQ/",
            "accession": "IGVFDS9780HOAQ",
            "aliases": [
                "igvf:corces_measurementSet_RP017_G3_RNA"
            ],
            "file_set_type": "experimental data",
            "lab": {
                "title": "Ryan Corces, Gladstone Institute UCSF"
            },
            "preferred_assay_title": "10x multiome",
            "status": "preview",
            "summary": "single-nucleus RNA sequencing assay (10x multiome)"
        }
    ],
    "institutional_certificates": [
        {
            "@id": "/institutional-certificates/f7742e0d-bba4-4ca3-ab80-71c7364f24e7/",
            "certificate_identifier": "IP115-05",
            "controlled_access": false,
            "status": "in progress"
        }
    ],
    "lab": {
        "@id": "/labs/ryan-corces/",
        "title": "Ryan Corces, Gladstone Institute UCSF"
    },
    "lower_bound_age": 87,
    "lower_bound_age_in_hours": 762120,
    "multiplexed_in": [
        {
            "@id": "/multiplexed-samples/IGVFSM0227NNUH/",
            "accession": "IGVFSM0227NNUH",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM5256WGBP/",
            "accession": "IGVFSM5256WGBP",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM7862ZFRE/",
            "accession": "IGVFSM7862ZFRE",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM0150MSRW/",
            "accession": "IGVFSM0150MSRW",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM2056FRDV/",
            "accession": "IGVFSM2056FRDV",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM0003YDGL/",
            "accession": "IGVFSM0003YDGL",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM1370NRUL/",
            "accession": "IGVFSM1370NRUL",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM3682UJBY/",
            "accession": "IGVFSM3682UJBY",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM6377ARDR/",
            "accession": "IGVFSM6377ARDR",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM0214EVMC/",
            "accession": "IGVFSM0214EVMC",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM8995INHU/",
            "accession": "IGVFSM8995INHU",
            "status": "preview"
        },
        {
            "@id": "/multiplexed-samples/IGVFSM6067ILMK/",
            "accession": "IGVFSM6067ILMK",
            "status": "preview"
        }
    ],
    "origin_of": [],
    "parts": [],
    "pmi": 189,
    "pmi_units": "minute",
    "pooled_in": [],
    "preservation_method": "flash-freezing",
    "protocols": [
        "https://www.protocols.io/view/isolation-of-nuclei-from-frozen-tissue-for-snmulti-6uchesw"
    ],
    "sample_terms": [
        {
            "@id": "/sample-terms/UBERON_0002038/",
            "status": "preview",
            "term_name": "substantia nigra"
        }
    ],
    "schema_version": "21",
    "sex": "male",
    "sorted_fractions": [],
    "sources": [
        {
            "@id": "/sources/banner-health/",
            "status": "released",
            "title": "Banner Health"
        }
    ],
    "status": "preview",
    "submitted_by": {
        "@id": "/users/c13db3ca-f844-4a69-9056-5fbc4a100f36/",
        "title": "Ryan Corces"
    },
    "summary": "Homo sapiens (male, 87 years) substantia nigra tissue associated with Parkinson's disease, cerebral amyloid angiopathy",
    "taxa": "Homo sapiens",
    "upper_bound_age": 87,
    "upper_bound_age_in_hours": 762120,
    "uuid": "5ed3c329-e74d-4bff-aa85-2674c8ebce99",
    "virtual": false
}