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154 items
  • intermediate
    AnalysisSet
    IGVFDS7903FOXV
    10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
    Ansuman Satpathy, Stanford
    Samples
    Homo sapiens multiplexed sample of GM25256 (WTC-11), H7-hESC
    released
  • principal
    AnalysisSet
    IGVFDS5394QLIN
    lentiMPRA: reporter genomic variant effects
    Nadav Ahituv, UCSF
    Samples
    Homo sapiens H1-hESC pooled differentiated cell specimen induced to glutamatergic neuron, at 7 day(s) post change, transfected with a reporter library
    released
  • intermediate
    AnalysisSet
    IGVFDS2296EFNK
    CRISPR HiCAR: contact matrix
    Charles Gersbach, Duke
    Samples
    Homo sapiens GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell, at 42 day(s) post change, perturbed with 1 μM Endothelin-1 for 3 days, transfected with a guide library
    released
  • principal
    AnalysisSet
    IGVFDS6344XBAV
    ATAC-seq: alignments, fold change over control, peak quantifications
    Charles Gersbach, Duke
    Samples
    Homo sapiens CD8-positive, alpha-beta memory T primary cell primary cell, stimulated with 300 percent Antibody Coated Bead for 14 days, transfected with a expression vector library
    released
  • principal
    AnalysisSet
    IGVFDS0577SVCR
    Proliferation CRISPR interference screen: guide quantifications
    Guillaume Lettre, MHI
    Samples
    Homo sapiens TeloHAEC cell line, modified with CRISPRi Sp-dCas9-KOX1-KRAB, transfected with a guide library
    released
  • intermediate
    AnalysisSet
    IGVFDS1949MRJM
    10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
    Ansuman Satpathy, Stanford
    Samples
    Homo sapiens multiplexed sample of GM25256 (WTC-11), H1-hESC, H9, HEK293T
    released
  • principal
    AnalysisSet
    IGVFDS0320JXJG
    CRISPR activation FACS screen targeting CCR7: alignments, fold change over control, guide quantifications
    Charles Gersbach, Duke
    Samples
    Homo sapiens CD8-positive, alpha-beta memory T primary cell primary cell, modified with CRISPRa Sa-dCas9-VP64, transfected with a guide library, sorted on expression of CCR7
    released
  • principal
    AnalysisSet
    IGVFDS4714VWGB
    SUPERSTARR: alignments, index, reporter genomic variant effects, reporter variants
    Tim Reddy, Duke
    Samples
    Homo sapiens K562 cell line, transfected with a reporter library
    released
  • intermediate
    AnalysisSet
    IGVFDS5192PMWB
    10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
    Ansuman Satpathy, Stanford
    Samples
    Homo sapiens multiplexed sample of H1-hESC
    released
  • intermediate
    AnalysisSet
    IGVFDS9608RUYZ
    CRISPR HiCAR: contact matrix
    Charles Gersbach, Duke
    Samples
    Homo sapiens GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell, at 42 day(s) post change, perturbed with 1 μM Endothelin-1 for 3 days, transfected with a guide library
    released
  • intermediate
    AnalysisSet
    IGVFDS8055FNVD
    CRISPR HiCAR: contact matrix
    Charles Gersbach, Duke
    Samples
    Homo sapiens GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell, at 42 day(s) post change, transfected with a guide library
    released
  • intermediate
    AnalysisSet
    IGVFDS3114UZXE
    10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
    Ansuman Satpathy, Stanford
    Samples
    Homo sapiens multiplexed sample of GM25256 (WTC-11)
    released
  • intermediate
    AnalysisSet
    IGVFDS9896QVZT
    10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
    Ansuman Satpathy, Stanford
    Samples
    Homo sapiens multiplexed sample of GM25256 (WTC-11), H9, HepG2
    released
  • intermediate
    AnalysisSet
    IGVFDS3159CKGQ
    CRISPR HiCAR: contact matrix
    Charles Gersbach, Duke
    Samples
    Mus musculus HL-1 cell line, transfected with a guide library
    released
  • intermediate
    AnalysisSet
    IGVFDS5153IDEO
    single-cell ATAC-seq (SHARE-seq), single-cell RNA sequencing assay (SHARE-seq): fragments, sparse gene count matrix
    Jason Buenrostro, Broad
    Samples
    Mus musculus colon tissue
    released
  • intermediate
    AnalysisSet
    IGVFDS0793KZKS
    10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
    Ansuman Satpathy, Stanford
    Samples
    Homo sapiens multiplexed sample of B cell, bone marrow
    released
  • principal
    AnalysisSet
    IGVFDS5056OAGR
    CRISPR prime editing Variant-EFFECTS targeting PPIF: variant effects
    Jesse Engreitz, Stanford
    Samples
    Homo sapiens THP-1 cell line, modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, sorted on expression of PPIF
    released
  • principal
    AnalysisSet
    IGVFDS2302NLIO
    ATAC-seq: alignments, fold change over control, peak quantifications
    Charles Gersbach, Duke
    Samples
    Homo sapiens CD8-positive, alpha-beta memory T primary cell primary cell, stimulated with 300 percent Antibody Coated Bead, transfected with a expression vector library
    released
  • intermediate
    AnalysisSet
    IGVFDS5322ZITQ
    CRISPR HiCAR: contact matrix
    Charles Gersbach, Duke
    Samples
    Homo sapiens GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell, at 42 day(s) post change, transfected with a guide library
    released
  • principal
    AnalysisSet
    IGVFDS3461ZPPS
    RNA-seq: fold change over control, transcript quantifications, transcriptome alignments
    Charles Gersbach, Duke
    Samples
    Homo sapiens GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell, at 28 day(s) post change, antagonized with 4 μM GSK3 inhibition for 7 days
    released
  • principal
    AnalysisSet
    IGVFDS6219XNKZ
    SUPERSTARR: alignments, index, reporter genomic variant effects, reporter variants
    Tim Reddy, Duke
    Samples
    Homo sapiens K562 cell line, transfected with a reporter library
    released
  • intermediate
    AnalysisSet
    IGVFDS6435ALNY
    10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
    Ansuman Satpathy, Stanford
    Samples
    Homo sapiens multiplexed sample of B cell
    released
  • principal
    AnalysisSet
    IGVFDS0120EBCZ
    Proliferation CRISPR mixed screen: guide quantifications, variant effects
    Daniel Bauer, HSCI
    Samples
    Homo sapiens HUDEP-2 cell line, modified with CRISPR base editing SpRY-ABE8e, CRISPR cutting SpRY, transfected with a guide library
    released
  • intermediate
    AnalysisSet
    IGVFDS9825AFPQ
    10x multiome with MULTI-seq: cell hashing barcodes, fragments, index, peaks, raw feature barcode matrix
    Ansuman Satpathy, Stanford
    Samples
    Homo sapiens multiplexed sample of induced pluripotent stem cell
    released
  • principal
    AnalysisSet
    IGVFDS7196OWBU
    CRISPR activation FACS screen targeting IL2RA: alignments, fold change over control, guide quantifications
    Charles Gersbach, Duke
    Samples
    Homo sapiens Jurkat cell line, modified with CRISPRa Sa-dCas9-2xVP64, transfected with a guide library, sorted on expression of IL2RA
    released