Homo sapiens (male) HepG2 cell line (sorting details: Sorted for Bottom 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
Richard Sherwood, Brigham and Women's Hospital
released
PrimaryCell
IGVFSM7452ZWAU
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 90-100% expression of b2m) modified with CRISPRi Sa-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
PrimaryCell
IGVFSM4508IIAY
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 90-100% expression of b2m) modified with CRISPRi Sa-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
InVitroSystem
IGVFSM9172BOGO
Homo sapiens (male) HepG2 cell line modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
Richard Sherwood, Brigham and Women's Hospital
released
PrimaryCell
IGVFSM7658WDNM
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 90-100% expression of CD2 ) modified with CRISPRi Sa-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
InVitroSystem
IGVFSM7036PBYG
Homo sapiens (male) HepG2 cell line modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
Richard Sherwood, Brigham and Women's Hospital
released
InVitroSystem
IGVFSM1838CFFU
Homo sapiens (male) Jurkat cell line (sorting details: FACS bin for 0-10% expression of IL2RA ) modified with CRISPRa Sa-dCas9-2xVP64, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
PrimaryCell
IGVFSM1190UUKW
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 0-10% expression of b2m) modified with CRISPRi Sa-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
InVitroSystem
IGVFSM0239RDRJ
Homo sapiens (male) HepG2 cell line (sorting details: Sorted for Bottom 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
Richard Sherwood, Brigham and Women's Hospital
released
InVitroSystem
IGVFSM4480HBZE
Homo sapiens (male) HepG2 cell line (sorting details: Sorted for Top 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
Richard Sherwood, Brigham and Women's Hospital
released
InVitroSystem
IGVFSM5112IFQB
Homo sapiens (male) Jurkat cell line (sorting details: FACS bin for 0-10% expression of IL2RA ) modified with CRISPRa Sa-dCas9-2xVP64, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
InVitroSystem
IGVFSM2152OUKV
Homo sapiens (male) HepG2 cell line (sorting details: Sorted for Bottom 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
Richard Sherwood, Brigham and Women's Hospital
released
PrimaryCell
IGVFSM7226CVDS
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 90-100% expression of IL7R) modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
PrimaryCell
IGVFSM8964QQSX
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 90-100% expression of CCR7) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
PrimaryCell
IGVFSM7418TTPB
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 0-10% expression of CCR7) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
InVitroSystem
IGVFSM6216RCYU
Homo sapiens (male) HepG2 cell line (sorting details: Sorted for Bottom 20-40% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
Richard Sherwood, Brigham and Women's Hospital
released
PrimaryCell
IGVFSM6062UNTJ
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 90-100% expression of b2m) modified with CRISPRi Sa-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
PrimaryCell
IGVFSM7030KVXG
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 90-100% expression of CD2) modified with CRISPRi Sa-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
PrimaryCell
IGVFSM3073WHFV
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 0-10% expression of b2m) modified with CRISPRi Sa-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
PrimaryCell
IGVFSM4936HKEW
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 0-10% expression of IL7R) modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
InVitroSystem
IGVFSM5703OIDJ
Homo sapiens (male) HepG2 cell line (sorting details: Sorted for Top 20% LDL-C uptake) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
Richard Sherwood, Brigham and Women's Hospital
released
InVitroSystem
IGVFSM6964ODEE
Homo sapiens (male) Jurkat cell line (sorting details: FACS bin for 90-100% expression of IL2RA ) modified with CRISPRa Sa-dCas9-2xVP64, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
PrimaryCell
IGVFSM4694MBIW
Homo sapiens CD8-positive, alpha-beta memory T cell (sorting details: FACS bin for 0-10% expression of CD2 ) modified with CRISPRi Sa-dCas9-KOX1-KRAB, transduced (lentivirus) with a guide library (MOI of 0.4)
Charles Gersbach, Duke
released
InVitroSystem
IGVFSM3582GWYM
Homo sapiens (male) HepG2 cell line modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library (MOI of 0.5)
Richard Sherwood, Brigham and Women's Hospital
released
InVitroSystem
IGVFSM3148FRBY
Homo sapiens (male) Jurkat cell line (sorting details: FACS bin for 90-100% expression of IL2RA ) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4)