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Multiplex profiling of developmental cis-regulatory elements with quantitative single-cell expression reporters

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Title
Multiplex profiling of developmental cis-regulatory elements with quantitative single-cell expression reporters
Authors
Jean-Benoît Lalanne, Samuel G. Regalado, Silvia Domcke, Diego Calderon, Beth K. Martin, Xiaoyi Li, Tony Li, Chase C. Suiter, Choli Lee, Cole Trapnell, Jay Shendure
Citation
Jean-Benoît Lalanne, Samuel G. Regalado, Silvia Domcke, Diego Calderon, Beth K. Martin, Xiaoyi Li, Tony Li, Chase C. Suiter, Choli Lee, Cole Trapnell, Jay Shendure (2024, May 9). Multiplex profiling of developmental cis-regulatory elements with quantitative single-cell expression reporters. Nature Methods.  
Publication Identifiers

Samples

50 items
Sample Terms
Summary
InVitroSystem
mouse embryonic stem differentiated cell specimen induced to embryoid body for 8 days, male, Mus musculus WD44 modified with a reporter library
InVitroSystem
mouse embryonic stem differentiated cell specimen induced to embryoid body for 21 days (cellular sub pool: 10Xlane1), male, Mus musculus WD44 modified with a reporter library
InVitroSystem
mouse embryonic stem differentiated cell specimen induced to embryoid body for 6 days, male, Mus musculus WD44 modified with a reporter library
InVitroSystem
mouse embryonic stem differentiated cell specimen induced to embryoid body for 12 days, male, Mus musculus WD44 modified with a reporter library
InVitroSystem
mouse embryonic stem differentiated cell specimen, male, Mus musculus WD44 modified with a reporter library
InVitroSystem
mouse embryonic stem differentiated cell specimen induced to embryoid body for 20 days, male, Mus musculus WD44 modified with a reporter library
InVitroSystem
mouse embryonic stem differentiated cell specimen induced to embryoid body for 21 days, male, Mus musculus WD44
InVitroSystem
mouse embryonic stem differentiated cell specimen induced to embryoid body for 18 days, male, Mus musculus WD44 modified with a reporter library
InVitroSystem
mouse embryonic stem differentiated cell specimen induced to embryoid body for 20 days, male, Mus musculus WD44 modified with a reporter library
InVitroSystem
mouse embryonic stem differentiated cell specimen induced to embryoid body for 12 days, male, Mus musculus WD44 modified with a reporter library

File Sets

101 items
AuxiliarySet
quantification DNA barcode sequencing for MPRA integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_repA_bulk_DNA_day20_reads
Jay Shendure, UW
AuxiliarySet
quantification DNA barcode sequencing for MPRA integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_repA_bulk_DNA_day21_reads
Jay Shendure, UW
MeasurementSet
MPRA integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_repB_bulk_RNA_day6_reads
Jay Shendure, UW
MeasurementSet
MPRA integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_repB_bulk_RNA_day0_reads
Jay Shendure, UW
MeasurementSet
MPRA (scQer) integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_GEx_repB_10Xlane1_reads
Jay Shendure, UW
MeasurementSet
MPRA integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_rep2B_part1_bulk_RNA_day8_reads
Jay Shendure, UW
AuxiliarySet
quantification DNA barcode sequencing for MPRA integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_repA_bulk_DNA_day10_reads
Jay Shendure, UW
MeasurementSet
MPRA integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_rep2B_part2_bulk_RNA_day20_reads
Jay Shendure, UW
MeasurementSet
MPRA integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_rep2B_part2_bulk_RNA_day8_reads
Jay Shendure, UW
MeasurementSet
MPRA integrating a reporter library targeting accessible genome regions in many genomic loci
  • jay-shendure:dev_CRE_mEBs_repB_bulk_RNA_day14_reads
Jay Shendure, UW

Attribution

Award
HG011966
Principal Investigator(s)
Contact P.I.
Jay Shendure
Lab
Jay Shendure, UW