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94 items
ATAC-seq
GRCh38
alignments
bam
intermediate analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens transduced (lentivirus) with a expression vector library
ATAC-seq: alignments
lentiMPRA
reporter genomic variant effects
tsv
principal analysis
neural progenitor pooled cell specimen, Homo sapiens transfected with a reporter library
lentiMPRA: reporter genomic variant effects
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens treated with 1 μM Endothelin-1 for 3 days, transfected with a guide library
HiCAR: contact matrix
ATAC-seq
GRCh38
fold change over control, peak quantifications
tsv
principal analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens transduced (lentivirus) with a expression vector library
ATAC-seq: fold change over control, peak quantifications
CRISPR FACS screen
custom
guide quantifications, fold change over control
csv, tsv
principal analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 0-10% expression of CCR7) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4), CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 90-100% expression of CCR7) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4)
CRISPR activation FACS screen targeting CCR7: fold change over control, guide quantifications
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens treated with 1 μM Endothelin-1 for 3 days, transfected with a guide library
HiCAR: contact matrix
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library
HiCAR: contact matrix
HiCAR
contact matrix
mcool, cool
intermediate analysis
HL-1 cell line, female, Mus musculus C57BL/6J transfected with a guide library
HiCAR: contact matrix
RNA-seq
GRCh38
transcriptome alignments
bam
intermediate analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4)
knockout RNA-seq: transcriptome alignments
Variant-EFFECTS
variant effects
tsv
principal analysis
THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 0-10% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 80-90% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 35-45% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 55-65% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 11-20% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library, THP-1 cell line, male, Homo sapiens modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), THP-1 cell line, male, Homo sapiens (sorting details: FACS bin for 90-100% expression of PPIF) modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library
prime editing Variant-EFFECTS targeting PPIF: variant effects
ATAC-seq
GRCh38
fold change over control, peak quantifications
tsv
principal analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens transduced (lentivirus) with a expression vector library
ATAC-seq: fold change over control, peak quantifications
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library
HiCAR: contact matrix
RNA-seq
GRCh38
transcript quantifications, fold change over control
tsv, csv
principal analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 28 days, male, Homo sapiens, GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 28 days, male, Homo sapiens treated with 4 μM GSK3 inhibition for 7 days
RNA-seq: fold change over control, transcript quantifications
CRISPR FACS screen
custom
alignments
bam
intermediate analysis
Jurkat cell line, Homo sapiens (sorting details: FACS bin for 90-100% expression of IL2RA ) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4), Jurkat cell line, Homo sapiens (sorting details: FACS bin for 0-10% expression of IL2RA ) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4)
CRISPR activation FACS screen targeting IL2RA: alignments
ATAC-seq
GRCh38
alignments
bam
intermediate analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens transduced (lentivirus) with a expression vector library
ATAC-seq: alignments
CRISPR FACS screen
custom
alignments
bam
intermediate analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 0-10% expression of CCR7) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4), CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 90-100% expression of CCR7) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4)
CRISPR activation FACS screen targeting CCR7: alignments
CRISPR FACS screen
custom
guide quantifications, fold change over control
csv, tsv
principal analysis
Jurkat cell line, Homo sapiens (sorting details: FACS bin for 90-100% expression of IL2RA ) modified with CRISPRa Sa-dCas9-2xVP64, transduced (lentivirus) with a guide library (MOI of 0.4), Jurkat cell line, Homo sapiens (sorting details: FACS bin for 0-10% expression of IL2RA ) modified with CRISPRa Sa-dCas9-2xVP64, transduced (lentivirus) with a guide library (MOI of 0.4)
CRISPR activation FACS screen targeting IL2RA: fold change over control, guide quantifications
CRISPR FACS screen
custom
alignments
bam
intermediate analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 0-10% expression of IL7R in cells overexpressing BATF3) modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4), CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 90-100% expression of IL7R in cells overexpressing BATF3) modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4)
CRISPR knockout FACS screen targeting IL7R: alignments
scATAC-seq
GRCm39
signal, fragments, peaks, sparse peak count matrix
bigWig, tsv, mtx
principal analysis
mouse embryonic stem differentiated cell specimen induced to embryoid body for 21 days (cellular sub pool: 10XlaneA), male, Mus musculus WD44, mouse embryonic stem differentiated cell specimen induced to embryoid body for 21 days (cellular sub pool: 10XlaneB), male, Mus musculus WD44
scATAC-seq: fragments, peaks, signal, sparse peak count matrix
HiCAR
GRCh38
differential chromatin contact quantifications, bin paired count
csv, tsv
principal analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens treated with 1 μM Endothelin-1 for 3 days, transfected with a guide library
HiCAR: bin paired count, differential chromatin contact quantifications
scCRISPR screen
sparse gene count matrix, differential gene expression quantifications
tar, csv
principal analysis
GM25256 (WTC-11) differentiated cell specimen induced to neuron for 19 days (cellular sub pool: 10Xlane1), male, Homo sapiens modified with CRISPRa Sp-dCas9-VPH, transfected with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to neuron for 19 days (cellular sub pool: 10Xlane4), male, Homo sapiens modified with CRISPRa Sp-dCas9-VPH, transfected with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to neuron for 19 days (cellular sub pool: 10Xlane3), male, Homo sapiens modified with CRISPRa Sp-dCas9-VPH, transfected with a guide library, GM25256 (WTC-11) differentiated cell specimen induced to neuron for 19 days (cellular sub pool: 10Xlane2), male, Homo sapiens modified with CRISPRa Sp-dCas9-VPH, transfected with a guide library
scCRISPR activation screen: differential gene expression quantifications, sparse gene count matrix
CRISPR FlowFISH screen
principal analysis
TeloHAEC cell line, female, Homo sapiens (sorting details: FACS bin for 76-100% expression of TLNRD1) modified with CRISPRi Sp-dCas9-KOX1-KRAB, transfected with a guide library, TeloHAEC cell line, female, Homo sapiens (sorting details: FACS bin for 51-75% expression of TLNRD1) modified with CRISPRi Sp-dCas9-KOX1-KRAB, transfected with a guide library, TeloHAEC cell line, female, Homo sapiens (sorting details: FACS bin for 26-50% expression of TLNRD1) modified with CRISPRi Sp-dCas9-KOX1-KRAB, transfected with a guide library, TeloHAEC cell line, female, Homo sapiens (sorting details: FACS bin for 0-25% expression of TLNRD1) modified with CRISPRi Sp-dCas9-KOX1-KRAB, transfected with a guide library
CRISPR interference FlowFISH screen targeting TLNRD1
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library
HiCAR: contact matrix
RNA-seq
GRCh38
transcriptome alignments
bam
intermediate analysis
CD8-positive, alpha-beta memory T cell, Homo sapiens modified with CRISPRko Sp-Cas9, transduced (lentivirus) with a guide library (MOI of 0.4)
knockout RNA-seq: transcriptome alignments
HiCAR
contact matrix
mcool, cool
intermediate analysis
GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens transfected with a guide library
HiCAR: contact matrix