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TeloHAEC — IGVFSM8257KOMT

released
Summary
Homo sapiens (female) TeloHAEC cell line modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library
Sample Terms
Classification
cell line
Sex
female
Age
unknown
Taxa
Homo sapiens
Sources
Guillaume Lettre, MHI
Aliases
guillaume-lettre:BP_screen_ABE8_D14_R2_1_ivs

Donors

1 item
Accession
Aliases
Sex
Taxa
  • igvf:donor_of_teloHAEC
female
Homo sapiens

File Sets

3 items
Proliferation CRISPR base editing screen: guide quantifications
  • guillaume-lettre:BP_ABE8_prolif_analysis_set
Guillaume Lettre, MHI
base editing Unspecified assay
  • guillaume-lettre:BP_mageck_ABE8_prolif_analysis_set
Guillaume Lettre, MHI
Proliferation CRISPR base editing screen integrating a guide (sgRNA) library targeting phenotype-associated variants genome-wide associated with blood pressure
  • guillaume-lettre:BP_screen_ABE8_D14_R2_1_ms
Guillaume Lettre, MHI

Modifications

1 item
Summary
Modality
Activation
base editing

Sorted Fractions of Sample

4 items
Sample Terms
Summary
InVitroSystem
Homo sapiens (female) TeloHAEC cell line (sorting details: FACS 60-80% expression of NFKBIA) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library
InVitroSystem
Homo sapiens (female) TeloHAEC cell line (sorting details: FACS 80-100% expression of NFKBIA) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library
InVitroSystem
Homo sapiens (female) TeloHAEC cell line (sorting details: FACS 20-40% expression of NFKBIA) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library
InVitroSystem
Homo sapiens (female) TeloHAEC cell line (sorting details: FACS 0-20% expression of NFKBIA) modified with CRISPR base editing SpRY-ABE8e, transduced (lentivirus) with a guide library

Attribution

Award
HG012010
Principal Investigator(s)
Contact P.I.
Luca Pinello
Lab
Guillaume Lettre, MHI