TeloHAEC — IGVFSM7589OEYV

released
{
    "@context": "/terms/",
    "@id": "/in-vitro-systems/IGVFSM7589OEYV/",
    "@type": [
        "InVitroSystem",
        "Biosample",
        "Sample",
        "Item"
    ],
    "accession": "IGVFSM7589OEYV",
    "age": "unknown",
    "aliases": [
        "jesse-engreitz:in-vitro-system_NOS3_CRISPRi_FF_R1_FFrep2"
    ],
    "audit": {
        "INTERNAL_ACTION": [
            {
                "category": "missing sequence specification",
                "detail": "Construct library set [IGVFDS8953DFJK](/construct-library-sets/IGVFDS8953DFJK/) has sequence file(s): [IGVFFI9158VFIB](/sequence-files/IGVFFI9158VFIB/), [IGVFFI7019XQBX](/sequence-files/IGVFFI7019XQBX/) which do not have any `seqspecs`. Sequence files in a file set are expected to link to a sequence specification file.",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_missing_seqspec",
                "path": "/construct-library-sets/IGVFDS8953DFJK/"
            },
            {
                "category": "NTR term ID",
                "detail": "Sample term for [NTR_0000753](/sample-terms/NTR_0000753/) has been newly requested. Ontology terms with a newly requested term ID are expected to have it updated following its addition to the appropriate ontology database.",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_ntr_term_id",
                "path": "/sample-terms/NTR_0000753/"
            }
        ],
        "NOT_COMPLIANT": [
            {
                "category": "missing analysis",
                "detail": "Construct library set [IGVFDS8953DFJK](/construct-library-sets/IGVFDS8953DFJK/) is a raw data set with files, but is not listed in any `input_file_sets` for any analysis sets. Raw data sets with files are expected to be associated with at least one analysis set.",
                "level": 50,
                "level_name": "NOT_COMPLIANT",
                "name": "audit_input_for",
                "path": "/construct-library-sets/IGVFDS8953DFJK/"
            }
        ]
    },
    "award": {
        "@id": "/awards/HG011972/",
        "component": "functional characterization"
    },
    "classifications": [
        "cell line"
    ],
    "construct_library_sets": [
        {
            "@id": "/construct-library-sets/IGVFDS8953DFJK/",
            "accession": "IGVFDS8953DFJK",
            "file_set_type": "guide library",
            "status": "released"
        }
    ],
    "creation_timestamp": "2024-04-15T19:25:16.280156+00:00",
    "demultiplexed_to": [],
    "donors": [
        "/human-donors/IGVFDO3459DFTW/"
    ],
    "file_sets": [],
    "institutional_certificates": [],
    "lab": {
        "@id": "/labs/jesse-engreitz/",
        "title": "Jesse Engreitz, Stanford"
    },
    "modifications": [
        {
            "@id": "/crispr-modifications/b4bc725a-8eeb-4180-9789-bece3516c0c1/",
            "cas": "dCas9",
            "cas_species": "Streptococcus pyogenes (Sp)",
            "fused_domain": "KOX1-KRAB",
            "modality": "interference",
            "status": "released",
            "summary": "CRISPRi Sp-dCas9-KOX1-KRAB"
        }
    ],
    "multiplexed_in": [],
    "notes": "This sample's modifications originally included Modification /modifications/2ba01755-df67-453b-b047-f7cdba236665/ which was deleted and replaced with a Crispr Modification igvf:replacement_of_2ba01755-df67-453b-b047-f7cdba236665.",
    "origin_of": [],
    "part_of": "/in-vitro-systems/IGVFSM1085KVBF/",
    "parts": [],
    "pooled_in": [],
    "release_timestamp": "2024-06-22T00:20:31.348337+00:00",
    "sample_terms": [
        {
            "@id": "/sample-terms/NTR_0000753/",
            "status": "released",
            "term_name": "TeloHAEC"
        }
    ],
    "schema_version": "23",
    "sex": "female",
    "sorted_fractions": [
        "/in-vitro-systems/IGVFSM4464SPLF/",
        "/in-vitro-systems/IGVFSM4987QNQG/",
        "/in-vitro-systems/IGVFSM6512KVQX/",
        "/in-vitro-systems/IGVFSM7665HTFX/",
        "/in-vitro-systems/IGVFSM4227JQMA/",
        "/in-vitro-systems/IGVFSM8817SMTB/",
        "/in-vitro-systems/IGVFSM4345IGSA/",
        "/in-vitro-systems/IGVFSM3569XFKY/"
    ],
    "sources": [
        {
            "@id": "/sources/atcc/",
            "status": "released",
            "title": "ATCC"
        }
    ],
    "status": "released",
    "submitted_by": {
        "@id": "/users/3bd6f74c-8cf3-4c35-a94d-0c7c11654815/",
        "title": "Chongyon Park"
    },
    "summary": "TeloHAEC cell line, female, Homo sapiens modified with CRISPRi Sp-dCas9-KOX1-KRAB, transfected with a guide library",
    "taxa": "Homo sapiens",
    "uuid": "9f7d5482-96ab-4142-b922-37e327024de5",
    "virtual": false
}