{
"@context": "/terms/",
"@id": "/in-vitro-systems/IGVFSM7176NKKR/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM7176NKKR",
"age": "unknown",
"aliases": [
"charles-gersbach:in-vitro-system-crispra-control-1umET1-ipsc-cm-targeted-hicar-rep2"
],
"audit": {
"WARNING": [
{
"category": "missing files",
"detail": "Construct library set [IGVFDS6209EFIL](/construct-library-sets/IGVFDS6209EFIL/) has no `files`. File sets are expected to have files.",
"level": 40,
"level_name": "WARNING",
"name": "audit_no_files",
"path": "/construct-library-sets/IGVFDS6209EFIL/"
}
]
},
"award": {
"@id": "/awards/HG012053/",
"component": "functional characterization"
},
"cell_fate_change_protocol": "/documents/b705a1b0-8936-464e-84e1-c4d2b3df7711/",
"classifications": [
"differentiated cell specimen"
],
"construct_library_sets": [
{
"@id": "/construct-library-sets/IGVFDS6209EFIL/",
"accession": "IGVFDS6209EFIL",
"file_set_type": "guide library",
"status": "released"
}
],
"creation_timestamp": "2024-10-23T19:06:00.689490+00:00",
"demultiplexed_to": [],
"donors": [
"/human-donors/IGVFDO3212TBUN/"
],
"file_sets": [
{
"@id": "/measurement-sets/IGVFDS6748EEVW/",
"accession": "IGVFDS6748EEVW",
"aliases": [
"charles-gersbach:measurement-set-crispra-control-1umET1-ipsc-cm-targeted-hicar-rep2"
],
"file_set_type": "experimental data",
"lab": {
"title": "Charles Gersbach, Duke"
},
"preferred_assay_title": "HiCAR",
"status": "released",
"summary": "CRISPR HiCAR integrating a non-targeting guide (sgRNA) library"
},
{
"@id": "/analysis-sets/IGVFDS0561MJAA/",
"accession": "IGVFDS0561MJAA",
"aliases": [
"charles-gersbach:analysis-set-crispra-control-1umET1-ipsc-cm-targeted-hicar-rep2-cool"
],
"file_set_type": "intermediate analysis",
"lab": {
"title": "Charles Gersbach, Duke"
},
"status": "released",
"summary": "HiCAR: contact matrix"
},
{
"@id": "/analysis-sets/IGVFDS2248ZJTA/",
"accession": "IGVFDS2248ZJTA",
"aliases": [
"charles-gersbach:analysis-set-crispra-stim-ctrl-NT-DEanalysis"
],
"file_set_type": "principal analysis",
"lab": {
"title": "Charles Gersbach, Duke"
},
"status": "released",
"summary": "HiCAR: bin paired count, differential chromatin contact quantifications"
},
{
"@id": "/analysis-sets/IGVFDS7797WATU/",
"accession": "IGVFDS7797WATU",
"aliases": [
"charles-gersbach:analysis-set-crispra-stim-NT-region3-DEanalysis"
],
"file_set_type": "principal analysis",
"lab": {
"title": "Charles Gersbach, Duke"
},
"status": "released",
"summary": "HiCAR: bin paired count, differential chromatin contact quantifications"
}
],
"institutional_certificates": [
{
"@id": "/institutional-certificates/a62cea9b-2ae0-44e8-a6d6-81f419c56c71/",
"certificate_identifier": "IP117-03",
"status": "released"
}
],
"lab": {
"@id": "/labs/charles-gersbach/",
"title": "Charles Gersbach, Duke"
},
"multiplexed_in": [],
"origin_of": [],
"parts": [],
"pooled_in": [],
"release_timestamp": "2024-12-13T19:43:54.322040+00:00",
"sample_terms": [
{
"@id": "/sample-terms/EFO_0009747/",
"status": "released",
"term_name": "GM25256 (WTC-11)"
}
],
"schema_version": "23",
"sex": "male",
"sorted_fractions": [],
"sources": [
{
"@id": "/labs/charles-gersbach/",
"status": "current",
"title": "Charles Gersbach, Duke"
}
],
"status": "released",
"submitted_by": {
"@id": "/users/3782ce69-0e9f-4b46-91f9-4578139785c7/",
"title": "Ruhi Rai"
},
"summary": "GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens treated with 1 μM Endothelin-1 for 3 days, transfected with a guide library",
"targeted_sample_term": {
"@id": "/sample-terms/CL_0000746/",
"status": "released",
"term_name": "cardiac muscle cell"
},
"taxa": "Homo sapiens",
"time_post_change": 42,
"time_post_change_units": "day",
"treatments": [
{
"@id": "/treatments/bbe5df8d-a9e2-4a99-8942-9b3b7d12c605/",
"depletion": false,
"purpose": "perturbation",
"status": "released",
"treatment_term_name": "Endothelin-1",
"treatment_type": "chemical"
}
],
"uuid": "f3ffa5f3-d214-4729-909d-fd5f8a228efd",
"virtual": false
}