THP-1 — IGVFSM2858MTZW

preview

This object is in preview status. Metadata is subject to change until this object is released.

Summary

THP-1 cell line, male, Homo sapiens modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library

Sample Terms

THP-1

Classification

cell line

Sex

male

Age

unknown

Part of Sample

IGVFSM3498MEQA

Construct Library Sets

IGVFDS9097TEUZ guide (sgRNA) library targeting sequence variants in a genomic locus

Taxa

Homo sapiens

Sources

atcc

Aliases

jesse-engreitz:240908-S029-PPIF_5SpliceSite-IndividualVariantExp-AGGT_TCCA-THP1-BioRep2

Protocols

https://www.protocols.io/view/flowfish-with-primeflow-36wgq3q4olk5/v1

Donors

1 item

Accession

Aliases

Sex

Taxa

IGVFDO7359LVPI

igvf:donor_of_THP1

male

Homo sapiens

Sample Parts

2 items

Sample Terms

Summary

IGVFSM5591SCVW

InVitroSystem

THP-1

THP-1 cell line, male, Homo sapiens modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library

IGVFSM6035MJZB

InVitroSystem

THP-1

THP-1 cell line, male, Homo sapiens modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library

Modifications

1 item

Summary

Modality

Activation

CRISPR prime editing Sp-nCas9-M-MLV RT (PE2)

prime editing

Attribution

Award

HG011972

Principal Investigator(s)

Anshul Kundaje, Jesse Engreitz, Marlene Rabinovitch, Lars Steinmetz, Michael Bassik, Thomas Quertermous, Will Greenleaf

Contact P.I.

Jesse Engreitz

Lab

Jesse Engreitz, Stanford