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K562 — IGVFSM1594ZOQH

released
Summary
K562 cell line (cellular sub pool: 10Xlane1), female, Homo sapiens modified with CRISPRa Sp-dCas9-VP64-p65-Rta (VPR), transfected with a guide library
Sample Terms
Classification
cell line
Sex
female
Cellular Sub Pool
10Xlane1
Age
unknown
Part of Sample
IGVFSM8338YZLA
Construct Library Sets
  • IGVFDS7581DNXF guide (sgRNA) library targeting TF binding sites, candidate cis-regulatory elements in many genomic loci
Taxa
Homo sapiens
Sources
horizondiscovery HD_dCas9-VPR-005
Additional Information
https://horizondiscovery.com/en/engineered-cell-lines/products/dcas9-vpr-stable-cell-line
External Resources
Aliases
jay-shendure:CRISPRa_VPR_K562_10Xlane1
Publications

Donors

1 item
Accession
Aliases
Sex
Taxa
  • igvf:donor_of_K562
female
Homo sapiens

File Sets

3 items
gRNA sequencing for scCRISPR activation screen integrating a guide (sgRNA) library targeting TF binding sites, candidate cis-regulatory elements in many genomic loci
  • jay-shendure:CRISPRa_singlecell_K562_VPR_10Xlane1_CS1
Jay Shendure, UW
scCRISPR activation screen integrating a guide (sgRNA) library targeting TF binding sites, candidate cis-regulatory elements in many genomic loci
  • jay-shendure:CRISPRa_singlecell_K562_VPR_10Xlane1_exprs
Jay Shendure, UW
scCRISPR activation screen: differential gene expression quantifications, filtered feature barcode matrix
  • jay-shendure:analysis_set_CRISPRa_K562
Jay Shendure, UW

Modifications

1 item
Summary
Modality
Activation
activation

Attribution

Award
HG011966
Principal Investigator(s)
Contact P.I.
Jay Shendure
Lab
Jay Shendure, UW