The goals of the IGVF Data Administrative and Coordinating Center (DACC) are to support the IGVF Consortium by defining and establishing a strategy that connects all participants to the project’s science. By creating avenues of access that distribute these data to the greater biological research community, the DACC provides a critical connection between scientific producers and consumers.

HG012012

A Data and Administrative Coordinating Center for the Impact of Genomic Variation on Function Consortium

j-michael-cherry

Corinn Small

J. Michael Cherry, Stanford

J. Michael Cherry

HG011969

The Center for Actionable Variant Analysis; measuring variant function at scale

HG012003

Systematic in vivo characterization of disease-associated regulatory variants

HG011972

Stanford Center for Connecting DNA Variants to Function and Phenotype

HG011989

Molecular phenotyping of ~100,000 coding variants across Mendelian disease genes

HG012079

Leveraging genetic variation to dissect gene regulatory networks of reprogramming to pluripotency

HG011966

Massively parallel characterization of variants and elements impacting transcriptional regulation in dynamic cellular systems

HG012053

High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular Phenotypes

HG012047

Defining causal roles of genomic variants on gene regulatory networks with spatiotemporally-resolved single-cell multiomics

Community

HG011952

Predicting the Impact of Genomic Variation on Cellular States

HG011967

Design, prediction, and prioritization of systematic perturbations of the human genome

HG012039

Linking Variants to Multi-scale Phenotypes via a Synthesis of Subnetwork Inference and Deep Learning

HG012051

Genomic control of gene regulatory networks governing early human lineage decisions

HG012064

Predictive Modeling of the Functional and Phenotypic Impacts of Genetic Variants

HG011996

Multiscale functional characterization of genomic variation in human developmental disorders

HG012041

Linking genome variation to transcriptional network dynamics in human B cells

HG012059

The impact of genomic variation on environment-induced changes in pancreatic beta-cell states

R00HG012203

New Approaches for leveraging single-cell data to identify disease-critical genes and gene sets

HG012070

WashU-Northwestern Genomic Variation and Function Data and Administrative Coordinating Center

HG012077

Center for Mouse Genomic Variation at Single Cell Resolution

affiliate

IGVF affiliate

ENCODE

HG012009

Predicting the impact of genetic variants, genes and pathways on human disease

HG012010

Comprehensive characterization of variants underlying heart and blood diseases with CRISPR base editing

HG012103

Deciphering the Genomics of Gene Network Regulation of T Cell and Fibroblast States in Autoimmune Inflammation

HG011986

A foundational resource of functional elements, TF footprints and gene regulatory interactions

HG012022

Supporting IGVF by modeling genetics, function, and phenotype with machine learning

HG012069

Predicting context-specific molecular and phenotypic effects of genetic variation through the lens of the cis-regulatory code

HG012076

Single-cell Mapping Center for Human Regulatory Elements and Gene Activity

data-submission

Khine Lin

Data Submission[nopanel]

lars-steinmetz

Lars Steinmetz, Stanford

sreeram-kannan

Sreeram Kannan, UPenn

shamil-sunyaev

Shamil Sunyaev, Brigham and Women's Hospital

marc-vidal

Marc Vidal, DFCI

michael-beer

Michael Beer, JHU

kathrin-plath

Kathrin Plath, UCLA

joshua-welch

Joshua Welch, UMich

bradley-bernstein

Bradley Bernstein, Broad

ryan-corces

Ryan Corces, Gladstone Institute UCSF

bill-majoros

Bill Majoros, Duke

benjamin-kleinstiver

Benjamin Kleinstiver, MGH

luca-pinello

Luca Pinello, MGH

noah-zaitlen

Noah Zaitlen, UCSF

ali-mortazavi

Ali Mortazavi, UCI

alkes-price

Alkes Price, Harvard

vikas-pejaver

Vikas Pejaver, MSSM

hongjun-song

Hongjun Song, UPenn

katie-pollard

Katie Pollard, UCSF

sean-mooney

Sean Mooney, UW

marlene-rabinovitch

Marlene Rabinovitch, Stanford

jonathan-pritchard

Jonathan Pritchard, Stanford

predrag-radivojac

Predrag Radivojac, Northeastern

lior-pachter

Lior Pachter, Caltech

chongyuan-luo

Chongyuan Luo, UCLA

danwei-huangfu

Danwei Huangfu, MSKCC

kyle-gaulton

Kyle Gaulton, UCSD

gary-hon

Gary Hon, UT

leif-ludwig

Leif Ludwig, MDC

jimmie-ye

Jimmie Ye, UCSF

hannah-carter

Hannah Carter, UCSD

nadav-ahituv

Nadav Ahituv, UCSF

encode

ENCODE Project, NHGRI

maike-sander

Maike Sander, UCSD

doug-fowler

Doug Fowler, UW

gregory-crawford

Gregory Crawford, Duke

robert-steiner

Robert Steiner, PreventionGenetics

david-hill

David Hill, DFCI

maria-chahrour

Maria Chahrour, UT

manuel-garber

Manuel Garber, UMass

alan-boyle

Alan Boyle, UMich

karen-mohlke

Karen Mohlke, UNC

hilary-finucane

Hilary Finucane, Broad

anshul-kundaje

Anshul Kundaje, Stanford

richard-sherwood

Richard Sherwood, Brigham and Women's Hospital

will-greenleaf

Will Greenleaf, Stanford

ryan-mills

Ryan Mills, UMich

michael-love

Michael Love, UNC

ansuman-satpathy

Ansuman Satpathy, Stanford

alexis-battle

Alexis Battle, JHU

judy-cho

Judy Cho, Ichan School of Medicine at Mount Sinai

tom-norman

Tom Norman, MSKCC

anne-carpenter

Anne Carpenter, Broad

bing-ren

Bing Ren, UCSD

bruce-posner

Bruce Posner, UT

stephen-montgomery

Stephen Montgomery, Stanford

nikhil-munshi

Nikhil Munshi, UT

jason-buenrostro

Jason Buenrostro, Broad

kushal-dey

Kushal Dey, MSKCC

hyejung-won

Hyejung Won, UNC

hao-wu

Hao Wu, UPenn

steven-gazal

Steven Gazal, USC

feng-yue

Feng Yue, WashU

axel-visel

Axel Visel, Lawrence Berkeley

soumya-raychaudhuri

Soumya Raychaudhuri, Brigham and Women's Hospital

harinder-singh

Harinder Singh, University of Pittsburgh

grant-macgregor

Grant MacGregor, UCI

maureen-sartor

Maureen Sartor, UMich

mikko-taipale

Mikko Taipale, UToronto