CRISPRi Sp-dCas9-KOX1-KRAB

released
{
    "@context": "/terms/",
    "@id": "/crispr-modifications/8543fa06-1720-4e7d-8e8f-7e24c1b1cf79/",
    "@type": [
        "CrisprModification",
        "Modification",
        "Item"
    ],
    "aliases": [
        "igvf:replacement_of_56d6a4f4-5fa4-4989-890e-aafb032f1e7d",
        "jesse-engreitz:in-vitro-system_CRUDO_SpdCas9-KRAB"
    ],
    "audit": {},
    "award": {
        "@id": "/awards/HG011972/",
        "component": "functional characterization"
    },
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        "/in-vitro-systems/IGVFSM6811XGTM/",
        "/in-vitro-systems/IGVFSM9894YYOA/",
        "/in-vitro-systems/IGVFSM1725FTKZ/",
        "/in-vitro-systems/IGVFSM4779RXHT/",
        "/in-vitro-systems/IGVFSM8586BMQG/",
        "/in-vitro-systems/IGVFSM6864OXRH/",
        "/in-vitro-systems/IGVFSM3595PQEE/",
        "/in-vitro-systems/IGVFSM0264XNND/",
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        "/in-vitro-systems/IGVFSM9603ZYAW/",
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        "/in-vitro-systems/IGVFSM4919VWFX/",
        "/in-vitro-systems/IGVFSM5357VTYO/",
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        "/in-vitro-systems/IGVFSM3954RGXF/",
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        "/in-vitro-systems/IGVFSM6932DXSV/",
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        "/in-vitro-systems/IGVFSM0561OELB/",
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        "/in-vitro-systems/IGVFSM3963KBYF/",
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        "/in-vitro-systems/IGVFSM4218VHTT/",
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        "/in-vitro-systems/IGVFSM2476YZDG/",
        "/in-vitro-systems/IGVFSM3998EEZS/",
        "/in-vitro-systems/IGVFSM0596STHT/",
        "/in-vitro-systems/IGVFSM0637ZUKN/",
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        "/in-vitro-systems/IGVFSM0890WDDX/",
        "/in-vitro-systems/IGVFSM5410WZKF/",
        "/in-vitro-systems/IGVFSM3263KXLP/",
        "/in-vitro-systems/IGVFSM5079ZTJX/",
        "/in-vitro-systems/IGVFSM1476QKIB/",
        "/in-vitro-systems/IGVFSM7739FHWE/",
        "/in-vitro-systems/IGVFSM8090YJPJ/",
        "/in-vitro-systems/IGVFSM0606BETP/",
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        "/in-vitro-systems/IGVFSM1961BHPA/",
        "/in-vitro-systems/IGVFSM8111MLZW/"
    ],
    "cas": "dCas9",
    "cas_species": "Streptococcus pyogenes (Sp)",
    "creation_timestamp": "2024-06-27T20:48:09.728806+00:00",
    "documents": [
        "/documents/d2f1ed4f-d62a-471b-9e76-d5d8c77b072e/"
    ],
    "fused_domain": "KOX1-KRAB",
    "lab": {
        "@id": "/labs/jesse-engreitz/",
        "title": "Jesse Engreitz, Stanford"
    },
    "modality": "interference",
    "notes": "Fused_domain enum KRAB has been removed.",
    "release_timestamp": "2024-07-10T19:37:41.320838+00:00",
    "schema_version": "3",
    "sources": [
        "/labs/jesse-engreitz/"
    ],
    "status": "released",
    "submitted_by": {
        "@id": "/users/43f2f757-5cbf-490a-9787-a1ee85a4cdcd/",
        "title": "Jennifer Jou"
    },
    "submitter_comment": "This Crispr Modification is an identical replacement of the previously submitted Modification 56d6a4f4-5fa4-4989-890e-aafb032f1e7d.",
    "summary": "CRISPRi Sp-dCas9-KOX1-KRAB",
    "uuid": "8543fa06-1720-4e7d-8e8f-7e24c1b1cf79"
}