CRISPRa Sa-dCas9-VP64

{
    "@context": "/terms/",
    "@id": "/crispr-modifications/2c49eb31-f10b-47b7-b260-4f720014ad79/",
    "@type": [
        "CrisprModification",
        "Modification",
        "Item"
    ],
    "aliases": [
        "charles-gersbach:dcas9-crispra-vp64",
        "igvf:replacement_of_38ecc9b0-19a4-4834-bab3-4d8367119377"
    ],
    "audit": {},
    "award": {
        "@id": "/awards/HG012053/",
        "component": "functional characterization"
    },
    "biosamples_modified": [
        "/primary-cells/IGVFSM7634EVUP/",
        "/primary-cells/IGVFSM1108NFPI/",
        "/primary-cells/IGVFSM7890DZST/",
        "/primary-cells/IGVFSM2105CLXS/",
        "/primary-cells/IGVFSM7418TTPB/",
        "/primary-cells/IGVFSM8036VPRU/",
        "/primary-cells/IGVFSM6223YCQV/",
        "/primary-cells/IGVFSM8964QQSX/",
        "/primary-cells/IGVFSM4110AXZO/",
        "/primary-cells/IGVFSM6002TGBI/",
        "/primary-cells/IGVFSM1721KPGX/",
        "/primary-cells/IGVFSM1343OUDU/",
        "/in-vitro-systems/IGVFSM6373RONE/",
        "/in-vitro-systems/IGVFSM3148FRBY/",
        "/in-vitro-systems/IGVFSM2737ATVK/",
        "/in-vitro-systems/IGVFSM8744PJOL/",
        "/in-vitro-systems/IGVFSM6490XCFZ/",
        "/in-vitro-systems/IGVFSM7748IVLZ/",
        "/in-vitro-systems/IGVFSM3606VJWU/",
        "/in-vitro-systems/IGVFSM1480DJBL/",
        "/in-vitro-systems/IGVFSM4401YRWQ/"
    ],
    "cas": "dCas9",
    "cas_species": "Staphylococcus aureus (Sa)",
    "creation_timestamp": "2024-06-27T20:48:09.116731+00:00",
    "description": "In a lentiviral instead of AAV backbone",
    "fused_domain": "VP64",
    "lab": {
        "@id": "/labs/charles-gersbach/",
        "title": "Charles Gersbach, Duke"
    },
    "modality": "activation",
    "product_id": "addgene:115790",
    "release_timestamp": "2024-10-18T19:49:56.918189+00:00",
    "schema_version": "4",
    "sources": [
        "/sources/addgene/"
    ],
    "status": "released",
    "submitted_by": {
        "@id": "/users/43f2f757-5cbf-490a-9787-a1ee85a4cdcd/",
        "title": "Jennifer Jou"
    },
    "submitter_comment": "This Crispr Modification is an identical replacement of the previously submitted Modification 38ecc9b0-19a4-4834-bab3-4d8367119377.",
    "summary": "CRISPRa Sa-dCas9-VP64",
    "uuid": "2c49eb31-f10b-47b7-b260-4f720014ad79"
}