{
"@context": "/terms/",
"@id": "/crispr-modifications/0a63b754-eca4-44aa-bbc2-fccdc6c44fb5/",
"@type": [
"CrisprModification",
"Modification",
"Item"
],
"aliases": [
"igvf:replacement_of_5f12e117-5d61-464b-a1e5-c826c83d6b10",
"nikhil-munshi:CRISPRi-dCAS9-KRAB"
],
"audit": {},
"award": {
"@id": "/awards/HG011996/",
"component": "functional characterization"
},
"biosamples_modified": [
"/in-vitro-systems/IGVFSM8305VDSK/",
"/in-vitro-systems/IGVFSM6603AZNV/",
"/in-vitro-systems/IGVFSM0406AROH/",
"/in-vitro-systems/IGVFSM8998NMND/",
"/in-vitro-systems/IGVFSM7252MDDA/",
"/in-vitro-systems/IGVFSM5549YYLD/",
"/in-vitro-systems/IGVFSM6688AKWB/",
"/in-vitro-systems/IGVFSM5505FJQT/",
"/in-vitro-systems/IGVFSM7777NWOC/",
"/in-vitro-systems/IGVFSM6695BAJS/",
"/in-vitro-systems/IGVFSM5870VZNC/",
"/in-vitro-systems/IGVFSM8711LYWS/",
"/in-vitro-systems/IGVFSM8669CDTU/",
"/in-vitro-systems/IGVFSM3732SQRO/",
"/in-vitro-systems/IGVFSM8604ZDRA/",
"/in-vitro-systems/IGVFSM6491ARHW/",
"/in-vitro-systems/IGVFSM4031QMVL/",
"/in-vitro-systems/IGVFSM4986MYBW/",
"/in-vitro-systems/IGVFSM3108DHOE/",
"/in-vitro-systems/IGVFSM0922NMHF/",
"/in-vitro-systems/IGVFSM2488CEYJ/",
"/in-vitro-systems/IGVFSM9178RDCY/",
"/in-vitro-systems/IGVFSM4903JWZM/",
"/in-vitro-systems/IGVFSM0297RYZA/",
"/in-vitro-systems/IGVFSM8829EXNK/",
"/in-vitro-systems/IGVFSM4662FPCU/",
"/in-vitro-systems/IGVFSM7940UCWC/",
"/in-vitro-systems/IGVFSM9699TYED/",
"/in-vitro-systems/IGVFSM8318TINZ/",
"/in-vitro-systems/IGVFSM3150YWAB/",
"/in-vitro-systems/IGVFSM0240OHVC/",
"/in-vitro-systems/IGVFSM2419NCMQ/",
"/in-vitro-systems/IGVFSM3385LRLD/",
"/in-vitro-systems/IGVFSM1491ESJW/",
"/in-vitro-systems/IGVFSM5807EVOX/",
"/in-vitro-systems/IGVFSM5450WETV/",
"/in-vitro-systems/IGVFSM1797HHGD/",
"/in-vitro-systems/IGVFSM4493CVCW/",
"/in-vitro-systems/IGVFSM3102SFHV/",
"/in-vitro-systems/IGVFSM9922DIQM/",
"/in-vitro-systems/IGVFSM7555OHZB/",
"/in-vitro-systems/IGVFSM1293BUGP/",
"/in-vitro-systems/IGVFSM8493HLCV/",
"/in-vitro-systems/IGVFSM1876KJWW/",
"/in-vitro-systems/IGVFSM0893IVTF/",
"/in-vitro-systems/IGVFSM8889XSOR/",
"/in-vitro-systems/IGVFSM4157HAUL/",
"/in-vitro-systems/IGVFSM2127MVQH/",
"/in-vitro-systems/IGVFSM3839SOTK/",
"/in-vitro-systems/IGVFSM4418NJET/",
"/in-vitro-systems/IGVFSM3680SAKS/",
"/in-vitro-systems/IGVFSM8986CPUS/",
"/in-vitro-systems/IGVFSM3002CFHI/",
"/in-vitro-systems/IGVFSM0565MLZG/",
"/in-vitro-systems/IGVFSM9285BBSI/",
"/in-vitro-systems/IGVFSM5829AVCL/",
"/in-vitro-systems/IGVFSM4223TGND/",
"/in-vitro-systems/IGVFSM7766HOYF/",
"/in-vitro-systems/IGVFSM4335VSMK/",
"/in-vitro-systems/IGVFSM3015ZQZL/",
"/in-vitro-systems/IGVFSM4523MTBT/",
"/in-vitro-systems/IGVFSM8133YEXK/",
"/in-vitro-systems/IGVFSM1513DHGW/",
"/in-vitro-systems/IGVFSM8072YOLO/",
"/in-vitro-systems/IGVFSM2176YXFG/",
"/in-vitro-systems/IGVFSM6351SIZQ/",
"/in-vitro-systems/IGVFSM2726ORRN/",
"/in-vitro-systems/IGVFSM9223FAYO/",
"/in-vitro-systems/IGVFSM5628VVVG/",
"/in-vitro-systems/IGVFSM9326DRHX/",
"/in-vitro-systems/IGVFSM6716LOHW/",
"/in-vitro-systems/IGVFSM1597KVRS/",
"/in-vitro-systems/IGVFSM8137TZJW/",
"/in-vitro-systems/IGVFSM5657YKPN/",
"/in-vitro-systems/IGVFSM4953FLXN/",
"/in-vitro-systems/IGVFSM0956HKRJ/",
"/in-vitro-systems/IGVFSM0604KDJF/",
"/in-vitro-systems/IGVFSM2329UXLZ/",
"/in-vitro-systems/IGVFSM9532RAXS/",
"/in-vitro-systems/IGVFSM9371INZC/",
"/in-vitro-systems/IGVFSM5849QIEI/",
"/in-vitro-systems/IGVFSM2597WGYB/",
"/in-vitro-systems/IGVFSM7513BJDT/",
"/in-vitro-systems/IGVFSM7740VKXC/",
"/in-vitro-systems/IGVFSM5652SBGF/",
"/in-vitro-systems/IGVFSM0333RWYR/",
"/in-vitro-systems/IGVFSM1288TQKF/",
"/in-vitro-systems/IGVFSM7499ZWUW/",
"/in-vitro-systems/IGVFSM1608DJBB/",
"/in-vitro-systems/IGVFSM9411HZLU/",
"/in-vitro-systems/IGVFSM9036LWJT/",
"/in-vitro-systems/IGVFSM1972EKCJ/",
"/in-vitro-systems/IGVFSM0248SELV/",
"/in-vitro-systems/IGVFSM0981UTUA/",
"/in-vitro-systems/IGVFSM2930BIPX/",
"/in-vitro-systems/IGVFSM1063UQVF/",
"/in-vitro-systems/IGVFSM0559UNMK/",
"/in-vitro-systems/IGVFSM4700PDTH/",
"/in-vitro-systems/IGVFSM6628JOOL/",
"/in-vitro-systems/IGVFSM2709AONE/",
"/in-vitro-systems/IGVFSM8464JMJS/",
"/in-vitro-systems/IGVFSM7215JDPM/",
"/in-vitro-systems/IGVFSM1153INDY/",
"/in-vitro-systems/IGVFSM2215YBLM/",
"/in-vitro-systems/IGVFSM4930FDUF/",
"/in-vitro-systems/IGVFSM5931YWOD/",
"/in-vitro-systems/IGVFSM2469FDHI/",
"/in-vitro-systems/IGVFSM5987GMNW/",
"/in-vitro-systems/IGVFSM1486VOFT/",
"/in-vitro-systems/IGVFSM3963LJGV/",
"/in-vitro-systems/IGVFSM1783RMGS/",
"/in-vitro-systems/IGVFSM8646JNYN/",
"/in-vitro-systems/IGVFSM5117QARH/",
"/in-vitro-systems/IGVFSM5748SPYQ/",
"/in-vitro-systems/IGVFSM2503VHPE/",
"/in-vitro-systems/IGVFSM0677JQON/",
"/in-vitro-systems/IGVFSM1100VSAV/",
"/in-vitro-systems/IGVFSM9849XJIY/",
"/in-vitro-systems/IGVFSM6527PCEG/",
"/in-vitro-systems/IGVFSM2105TPXP/",
"/in-vitro-systems/IGVFSM7248AXMT/",
"/in-vitro-systems/IGVFSM7740IDNA/",
"/in-vitro-systems/IGVFSM3199IPUF/",
"/in-vitro-systems/IGVFSM2466UXHW/",
"/in-vitro-systems/IGVFSM1571ZJPR/",
"/in-vitro-systems/IGVFSM1407UFUA/",
"/in-vitro-systems/IGVFSM3276IAPL/",
"/in-vitro-systems/IGVFSM0582LVCA/",
"/in-vitro-systems/IGVFSM8752MVLX/",
"/in-vitro-systems/IGVFSM8396BAPD/",
"/in-vitro-systems/IGVFSM7651JQLX/",
"/in-vitro-systems/IGVFSM7965IUTO/",
"/in-vitro-systems/IGVFSM1262BMXZ/",
"/in-vitro-systems/IGVFSM2697SJYA/",
"/in-vitro-systems/IGVFSM5481HUWA/",
"/in-vitro-systems/IGVFSM1649MDAH/"
],
"cas": "dCas9",
"cas_species": "Streptococcus pyogenes (Sp)",
"creation_timestamp": "2024-06-27T20:48:10.230940+00:00",
"lab": {
"@id": "/labs/gary-hon/",
"title": "Gary Hon, UT"
},
"modality": "interference",
"notes": "Fused_domain enum KRAB has been removed.",
"schema_version": "4",
"sources": [
"/labs/nikhil-munshi/"
],
"status": "preview",
"submitted_by": {
"@id": "/users/43f2f757-5cbf-490a-9787-a1ee85a4cdcd/",
"title": "Jennifer Jou"
},
"submitter_comment": "This Crispr Modification is an identical replacement of the previously submitted Modification 5f12e117-5d61-464b-a1e5-c826c83d6b10.",
"summary": "CRISPRi Sp-dCas9",
"uuid": "0a63b754-eca4-44aa-bbc2-fccdc6c44fb5"
}