{
"@context": "/terms/",
"@id": "/construct-library-sets/IGVFDS6209EFIL/",
"@type": [
"ConstructLibrarySet",
"FileSet",
"Item"
],
"accession": "IGVFDS6209EFIL",
"aliases": [
"charles-gersbach:construct-library-set-crispra-control-1umET1-ipsc-cm-targeted-hicar"
],
"applied_to_samples": [
{
"@id": "/in-vitro-systems/IGVFSM7176NKKR/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM7176NKKR",
"aliases": [
"charles-gersbach:in-vitro-system-crispra-control-1umET1-ipsc-cm-targeted-hicar-rep2"
],
"classifications": [
"differentiated cell specimen"
],
"donors": [
{
"@id": "/human-donors/IGVFDO3212TBUN/",
"status": "released",
"taxa": "Homo sapiens"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0009747/",
"status": "released",
"term_name": "GM25256 (WTC-11)"
}
],
"status": "released",
"summary": "GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens treated with 1 μM Endothelin-1 for 3 days, transfected with a guide library",
"targeted_sample_term": {
"@id": "/sample-terms/CL_0000746/",
"status": "released",
"term_name": "cardiac muscle cell"
},
"treatments": [
{
"@id": "/treatments/bbe5df8d-a9e2-4a99-8942-9b3b7d12c605/",
"status": "released",
"summary": "Treatment of 1 μM Endothelin-1 for 3 days",
"treatment_term_name": "Endothelin-1"
}
]
},
{
"@id": "/in-vitro-systems/IGVFSM2698DFOT/",
"@type": [
"InVitroSystem",
"Biosample",
"Sample",
"Item"
],
"accession": "IGVFSM2698DFOT",
"aliases": [
"charles-gersbach:in-vitro-system-crispra-control-1umET1-ipsc-cm-targeted-hicar-rep1"
],
"classifications": [
"differentiated cell specimen"
],
"donors": [
{
"@id": "/human-donors/IGVFDO3212TBUN/",
"status": "released",
"taxa": "Homo sapiens"
}
],
"sample_terms": [
{
"@id": "/sample-terms/EFO_0009747/",
"status": "released",
"term_name": "GM25256 (WTC-11)"
}
],
"status": "released",
"summary": "GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 42 days, male, Homo sapiens treated with 1 μM Endothelin-1 for 3 days, transfected with a guide library",
"targeted_sample_term": {
"@id": "/sample-terms/CL_0000746/",
"status": "released",
"term_name": "cardiac muscle cell"
},
"treatments": [
{
"@id": "/treatments/bbe5df8d-a9e2-4a99-8942-9b3b7d12c605/",
"status": "released",
"summary": "Treatment of 1 μM Endothelin-1 for 3 days",
"treatment_term_name": "Endothelin-1"
}
]
}
],
"audit": {
"WARNING": [
{
"category": "missing files",
"detail": "Construct library set [IGVFDS6209EFIL](/construct-library-sets/IGVFDS6209EFIL/) has no `files`. File sets are expected to have files.",
"level": 40,
"level_name": "WARNING",
"name": "audit_no_files",
"path": "/construct-library-sets/IGVFDS6209EFIL/"
}
]
},
"award": {
"@id": "/awards/HG012053/",
"component": "functional characterization"
},
"control_for": [
{
"@id": "/construct-library-sets/IGVFDS5972DQKC/",
"accession": "IGVFDS5972DQKC",
"aliases": [
"charles-gersbach:construct-library-set-crispra-region3-1umET1-ipsc-cm-targeted-hicar"
],
"status": "released"
}
],
"control_type": "non-targeting",
"creation_timestamp": "2024-11-22T16:29:36.154393+00:00",
"description": "cardiac-myosin-enhancer (library-set-mouse-hicar-probe-library)",
"documents": [
"/documents/1a235ef5-1a3a-42f6-8e45-f269ce85e54e/"
],
"file_set_type": "guide library",
"files": [],
"guide_type": "sgRNA",
"input_for": [],
"integrated_content_files": [
{
"@id": "/tabular-files/IGVFFI7739QJBH/",
"accession": "IGVFFI7739QJBH",
"aliases": [
"charles-gersbach:tabular-file-human_NT"
],
"content_type": "guide RNA sequences",
"file_format": "tsv",
"status": "released",
"upload_status": "validation exempted"
}
],
"lab": {
"@id": "/labs/charles-gersbach/",
"title": "Charles Gersbach, Duke"
},
"release_timestamp": "2024-12-13T19:43:54.341162+00:00",
"schema_version": "10",
"scope": "control",
"selection_criteria": [
"accessible genome regions"
],
"status": "released",
"submitted_by": {
"@id": "/users/3782ce69-0e9f-4b46-91f9-4578139785c7/",
"title": "Ruhi Rai"
},
"summary": "non-targeting guide (sgRNA) library",
"uuid": "076677c1-13e5-44a8-9fa1-1365ed6fd4e5"
}