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INDEXED
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AuxiliarySet
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IGVFDS9310VIMF
IGVFDS9310VIMF
revoked
Json view
File Set Type
gRNA sequencing
Summary
gRNA sequencing
Aliases
charles-gersbach:cd8-tcells-auxiliary-set-crispra-ccr7-high-bin-rep3
Revoke Detail
This auxiliary set has been revoked as its files have been moved to the measurement set: /measurement-sets/IGVFDS5417LSWU/
Publications
Transcriptional and epigenetic regulators of human CD8+ T cell function identified through orthogonal CRISPR screens
Samples
1 item
Accession
Type
Sample Terms
Associated Construct Library Sets
Summary
IGVFSM1721KPGX
PrimaryCell
CD8-positive, alpha-beta memory T cell
IGVFDS4163YHBI
CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 90-100% expression of CCR7) modified with CRISPRa Sa-dCas9-VP64, transduced (lentivirus) with a guide library (MOI of 0.4)
Donors
1 item
Accession
Aliases
Sex
Taxa
IGVFDO4579FYIL
charles-gersbach:cd8-tcells-donor-22
unspecified
Homo sapiens
Associated Construct Library Sets
1 item
Accession
Summary
Library Design Files
IGVFDS4163YHBI
guide (sgRNA) library targeting transcription start sites in many genes
IGVFFI6308XVUC
Attribution
Award
HG012053
Principal Investigator(s)
Charles Gersbach
,
Gregory Crawford
,
Tim Reddy
Contact P.I.
Charles Gersbach
Lab
Charles Gersbach, Duke