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INDEXED
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AuxiliarySet
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IGVFDS4170XDRQ
IGVFDS4170XDRQ
revoked
Json view
File Set Type
gRNA sequencing
Summary
gRNA sequencing
Aliases
charles-gersbach:cd8-tcells-auxiliary-set-crispr-ko-tfome-batf3-over-low-bin-rep2
Revoke Detail
This auxiliary set has been revoked as its files have been moved to the measurement set: /measurement-sets/IGVFDS8967NSST/
Publications
Transcriptional and epigenetic regulators of human CD8+ T cell function identified through orthogonal CRISPR screens
Samples
1 item
Accession
Type
Sample Terms
Associated Construct Library Sets
Summary
IGVFSM7158ADKU
PrimaryCell
CD8-positive, alpha-beta memory T cell
IGVFDS3667PLQB
IGVFDS1868WXHB
CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 0-10% expression of IL7R in cells overexpressing BATF3) modified with CRISPRko Sp-Cas9, transduced (lentivirus) with multiple libraries (MOI of 0.4)
Donors
1 item
Accession
Aliases
Sex
Taxa
IGVFDO2763RVOY
charles-gersbach:cd8-tcells-donor-26
unspecified
Homo sapiens
Associated Construct Library Sets
2 items
Accession
Summary
Library Design Files
IGVFDS1868WXHB
expression vector library of BATF3
IGVFDS3667PLQB
guide (sgRNA) library targeting transcription start sites in many genes
IGVFFI9735DZKB
Attribution
Award
HG012053
Principal Investigator(s)
Charles Gersbach
,
Gregory Crawford
,
Tim Reddy
Contact P.I.
Charles Gersbach
Lab
Charles Gersbach, Duke