IGVFDS3944URNH

{
    "@context": "/terms/",
    "@id": "/auxiliary-sets/IGVFDS3944URNH/",
    "@type": [
        "AuxiliarySet",
        "FileSet",
        "Item"
    ],
    "accession": "IGVFDS3944URNH",
    "aliases": [
        "charles-gersbach:cd8-tcells-auxiliary-set-crispri-b2m-high-bin-rep2"
    ],
    "audit": {
        "ERROR": [
            {
                "category": "missing measurement set",
                "detail": "Auxiliary set [IGVFDS3944URNH](/auxiliary-sets/IGVFDS3944URNH/) is not associated with any `measurement_sets`. Auxiliary sets are expected to be associated with a measurement set(s).",
                "level": 60,
                "level_name": "ERROR",
                "name": "audit_missing_measurement_sets",
                "path": "/auxiliary-sets/IGVFDS3944URNH/"
            }
        ],
        "NOT_COMPLIANT": [
            {
                "category": "missing files",
                "detail": "Auxiliary set [IGVFDS3944URNH](/auxiliary-sets/IGVFDS3944URNH/) has no `files`. File sets are expected to have files.",
                "level": 50,
                "level_name": "NOT_COMPLIANT",
                "name": "audit_no_files",
                "path": "/auxiliary-sets/IGVFDS3944URNH/"
            }
        ],
        "WARNING": [
            {
                "category": "missing age",
                "detail": "Primary cell [IGVFSM4508IIAY](/primary-cells/IGVFSM4508IIAY/) is missing `upper_bound_age`, `lower_bound_age`, and `age_units`. Tissues, primary cells, and whole organisms are expected to specify a lower bound age, upper bound age, and age units.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_biosample_age",
                "path": "/primary-cells/IGVFSM4508IIAY/"
            }
        ]
    },
    "award": {
        "@id": "/awards/HG012053/",
        "component": "functional characterization",
        "contact_pi": {
            "@id": "/users/5d329c0e-3ea9-49bf-9bb9-844a53a882c0/",
            "title": "Charles Gersbach"
        },
        "title": "High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular Phenotypes"
    },
    "construct_library_sets": [
        {
            "@id": "/construct-library-sets/IGVFDS5026WRUO/",
            "accession": "IGVFDS5026WRUO",
            "file_set_type": "guide library",
            "integrated_content_files": [
                {
                    "@id": "/tabular-files/IGVFFI1466VTFO/",
                    "accession": "IGVFFI1466VTFO",
                    "content_type": "guide RNA sequences",
                    "status": "released",
                    "summary": "GRCh38 guide RNA sequences"
                }
            ],
            "status": "released",
            "summary": "guide (sgRNA) library targeting transcription start sites in B2M"
        }
    ],
    "control_for": [],
    "creation_timestamp": "2024-02-05T22:39:25.965795+00:00",
    "donors": [
        {
            "@id": "/human-donors/IGVFDO4200TDAP/",
            "accession": "IGVFDO4200TDAP",
            "aliases": [
                "charles-gersbach:cd8-tcells-donor-18"
            ],
            "sex": "unspecified",
            "status": "released",
            "taxa": "Homo sapiens"
        }
    ],
    "file_set_type": "gRNA sequencing",
    "files": [],
    "input_for": [],
    "lab": {
        "@id": "/labs/charles-gersbach/",
        "title": "Charles Gersbach, Duke"
    },
    "measurement_sets": [],
    "release_timestamp": "2024-11-18T21:09:14.782798+00:00",
    "revoke_detail": "This auxiliary set has been revoked as its files have been moved to the measurement set: /measurement-sets/IGVFDS7534QWMG/",
    "samples": [
        {
            "@id": "/primary-cells/IGVFSM4508IIAY/",
            "@type": [
                "PrimaryCell",
                "Biosample",
                "Sample",
                "Item"
            ],
            "accession": "IGVFSM4508IIAY",
            "aliases": [
                "charles-gersbach:cd8-tcells-primary-cell-crispri-b2m-high-bin-rep2"
            ],
            "classifications": [
                "primary cell"
            ],
            "institutional_certificates": [],
            "modifications": [
                {
                    "@id": "/crispr-modifications/95393c9a-637d-43f6-baf9-662e45d28d61/",
                    "modality": "interference",
                    "status": "released"
                }
            ],
            "sample_terms": [
                {
                    "@id": "/sample-terms/CL_0000909/",
                    "@type": [
                        "SampleTerm",
                        "OntologyTerm",
                        "Item"
                    ],
                    "status": "released",
                    "summary": "CD8-positive, alpha-beta memory T cell",
                    "term_name": "CD8-positive, alpha-beta memory T cell"
                }
            ],
            "status": "released",
            "summary": "CD8-positive, alpha-beta memory T cell, Homo sapiens (sorting details: FACS bin for 90-100% expression of b2m) modified with CRISPRi Sa-dCas9, transduced (lentivirus) with a guide library (MOI of 0.4)",
            "taxa": "Homo sapiens"
        }
    ],
    "schema_version": "12",
    "status": "revoked",
    "submitted_by": {
        "@id": "/users/29f5f78d-ac90-421e-90c6-a90e1dc407a7/",
        "title": "Alejandro Barrera"
    },
    "summary": "gRNA sequencing",
    "uuid": "7ac146eb-c7a2-428f-9cf3-f707ed1a1b0b"
}