IGVFDS3707AOAO

1{
2    "@context": "/terms/",
3    "@id": "/auxiliary-sets/IGVFDS3707AOAO/",
4    "@type": [
5        "AuxiliarySet",
6        "FileSet",
7        "Item"
8    ],
9    "accession": "IGVFDS3707AOAO",
10    "aliases": [
11        "charles-gersbach:jurkats-auxiliary-set-crispra-vp64x2-il2ra-low-bin-rep3"
12    ],
13    "audit": {
14        "ERROR": [
15            {
16                "category": "missing measurement set",
17                "detail": "Auxiliary set [IGVFDS3707AOAO](/auxiliary-sets/IGVFDS3707AOAO/) is not associated with any `measurement_sets`. Auxiliary sets are expected to be associated with a measurement set(s).",
18                "level": 60,
19                "level_name": "ERROR",
20                "name": "audit_missing_measurement_sets",
21                "path": "/auxiliary-sets/IGVFDS3707AOAO/"
22            }
23        ],
24        "NOT_COMPLIANT": [
25            {
26                "category": "missing files",
27                "detail": "Auxiliary set [IGVFDS3707AOAO](/auxiliary-sets/IGVFDS3707AOAO/) has no `files`. File sets are expected to have files.",
28                "level": 50,
29                "level_name": "NOT_COMPLIANT",
30                "name": "audit_no_files",
31                "path": "/auxiliary-sets/IGVFDS3707AOAO/"
32            }
33        ]
34    },
35    "award": {
36        "@id": "/awards/HG012053/",
37        "component": "functional characterization",
38        "contact_pi": {
39            "@id": "/users/5d329c0e-3ea9-49bf-9bb9-844a53a882c0/",
40            "title": "Charles Gersbach"
41        },
42        "title": "High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular Phenotypes"
43    },
44    "construct_library_sets": [
45        {
46            "@id": "/construct-library-sets/IGVFDS8183QSJO/",
47            "accession": "IGVFDS8183QSJO",
48            "file_set_type": "guide library",
49            "integrated_content_files": [
50                {
51                    "@id": "/tabular-files/IGVFFI1252VLIV/",
52                    "accession": "IGVFFI1252VLIV",
53                    "content_type": "guide RNA sequences",
54                    "status": "in progress",
55                    "summary": "GRCh38 guide RNA sequences"
56                }
57            ],
58            "status": "released",
59            "summary": "guide (sgRNA) library targeting transcription start sites in IL2RA"
60        }
61    ],
62    "control_for": [],
63    "creation_timestamp": "2024-02-05T22:40:27.671616+00:00",
64    "donors": [
65        {
66            "@id": "/human-donors/IGVFDO1080XFGV/",
67            "accession": "IGVFDO1080XFGV",
68            "aliases": [
69                "igvf:donor_of_Jurkat"
70            ],
71            "sex": "male",
72            "status": "released",
73            "taxa": "Homo sapiens"
74        }
75    ],
76    "file_set_type": "gRNA sequencing",
77    "files": [],
78    "input_for": [],
79    "lab": {
80        "@id": "/labs/charles-gersbach/",
81        "title": "Charles Gersbach, Duke"
82    },
83    "measurement_sets": [],
84    "release_timestamp": "2024-11-18T21:08:59.704515+00:00",
85    "revoke_detail": "This auxiliary set has been revoked as its files have been moved to the measurement set: /measurement-sets/IGVFDS4149GPKB/",
86    "samples": [
87        {
88            "@id": "/in-vitro-systems/IGVFSM5112IFQB/",
89            "@type": [
90                "InVitroSystem",
91                "Biosample",
92                "Sample",
93                "Item"
94            ],
95            "accession": "IGVFSM5112IFQB",
96            "aliases": [
97                "charles-gersbach:jurkats-in-vitro-system-crispra-vp64x2-il2ra-low-bin-rep3"
98            ],
99            "classifications": [
100                "cell line"
101            ],
102            "institutional_certificates": [],
103            "modifications": [
104                {
105                    "@id": "/crispr-modifications/4c532ce1-11aa-41be-9757-13923c19248b/",
106                    "modality": "activation",
107                    "status": "released"
108                }
109            ],
110            "sample_terms": [
111                {
112                    "@id": "/sample-terms/EFO_0002796/",
113                    "@type": [
114                        "SampleTerm",
115                        "OntologyTerm",
116                        "Item"
117                    ],
118                    "aliases": [
119                        "igvf:Jurkat"
120                    ],
121                    "status": "released",
122                    "summary": "Jurkat",
123                    "term_name": "Jurkat"
124                }
125            ],
126            "status": "released",
127            "summary": "Homo sapiens (male) Jurkat cell line (sorting details: FACS bin for 0-10% expression of IL2RA ) modified with CRISPRa Sa-dCas9-2xVP64, transduced (lentivirus) with a guide library (MOI of 0.4)",
128            "taxa": "Homo sapiens"
129        }
130    ],
131    "schema_version": "12",
132    "status": "revoked",
133    "submitted_by": {
134        "@id": "/users/29f5f78d-ac90-421e-90c6-a90e1dc407a7/",
135        "title": "Alejandro Barrera"
136    },
137    "summary": "gRNA sequencing",
138    "uuid": "4c00db72-281f-4683-8406-10783840db41"
139}