IGVFDS2136RFQE

{
    "@context": "/terms/",
    "@id": "/auxiliary-sets/IGVFDS2136RFQE/",
    "@type": [
        "AuxiliarySet",
        "FileSet",
        "Item"
    ],
    "accession": "IGVFDS2136RFQE",
    "aliases": [
        "gary-hon:CM_Pilot_2_PB_sgRNA_LW234"
    ],
    "audit": {
        "INTERNAL_ACTION": [
            {
                "category": "missing sequencing kit",
                "detail": "Auxiliary set [IGVFDS2136RFQE](/auxiliary-sets/IGVFDS2136RFQE/) has sequence file(s) [IGVFFI5301SVVG](/sequence-files/IGVFFI5301SVVG/), [IGVFFI9083IKUZ](/sequence-files/IGVFFI9083IKUZ/), [IGVFFI8490GAUK](/sequence-files/IGVFFI8490GAUK/), [IGVFFI6705RMUI](/sequence-files/IGVFFI6705RMUI/), [IGVFFI2829XKCE](/sequence-files/IGVFFI2829XKCE/), [IGVFFI1008SZVT](/sequence-files/IGVFFI1008SZVT/), [IGVFFI0084VSYK](/sequence-files/IGVFFI0084VSYK/), [IGVFFI5975FQYH](/sequence-files/IGVFFI5975FQYH/) which lack specification of a `sequencing_kit`. Sequence files should specify a sequencing kit.",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_inconsistent_sequencing_kit",
                "path": "/auxiliary-sets/IGVFDS2136RFQE/"
            },
            {
                "category": "missing sequence specification",
                "detail": "Auxiliary set [IGVFDS2136RFQE](/auxiliary-sets/IGVFDS2136RFQE/) has sequence file(s): [IGVFFI5301SVVG](/sequence-files/IGVFFI5301SVVG/), [IGVFFI9083IKUZ](/sequence-files/IGVFFI9083IKUZ/), [IGVFFI8490GAUK](/sequence-files/IGVFFI8490GAUK/), [IGVFFI6705RMUI](/sequence-files/IGVFFI6705RMUI/), [IGVFFI2829XKCE](/sequence-files/IGVFFI2829XKCE/), [IGVFFI1008SZVT](/sequence-files/IGVFFI1008SZVT/), [IGVFFI0084VSYK](/sequence-files/IGVFFI0084VSYK/), [IGVFFI5975FQYH](/sequence-files/IGVFFI5975FQYH/) which do not have any `seqspecs`. Sequence files in a file set are expected to link to a sequence specification file.",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_missing_seqspec",
                "path": "/auxiliary-sets/IGVFDS2136RFQE/"
            }
        ]
    },
    "award": {
        "@id": "/awards/HG011996/",
        "component": "functional characterization",
        "contact_pi": {
            "@id": "/users/95d84f03-8ce0-489c-a755-f33ced139c5d/",
            "title": "Gary Hon"
        },
        "title": "Multiscale functional characterization of genomic variation in human developmental disorders"
    },
    "control_for": [],
    "creation_timestamp": "2024-02-15T23:35:39.065151+00:00",
    "donors": [
        {
            "@id": "/human-donors/IGVFDO1756PPKO/",
            "accession": "IGVFDO1756PPKO",
            "aliases": [
                "igvf:donor_of_WTC11"
            ],
            "sex": "male",
            "status": "released",
            "taxa": "Homo sapiens"
        }
    ],
    "file_set_type": "gRNA sequencing",
    "files": [
        {
            "@id": "/sequence-files/IGVFFI5301SVVG/",
            "accession": "IGVFFI5301SVVG",
            "aliases": [
                "gary-hon:LW234B-2_1_R1"
            ],
            "content_type": "reads",
            "controlled_access": false,
            "creation_timestamp": "2024-02-21T18:24:49.660758+00:00",
            "file_format": "fastq",
            "file_size": 1110647424,
            "href": "/sequence-files/IGVFFI5301SVVG/@@download/IGVFFI5301SVVG.fastq.gz",
            "s3_uri": "s3://igvf-files/2024/02/21/07f1d2c3-d3d0-4c70-810e-2e7675eb3858/IGVFFI5301SVVG.fastq.gz",
            "sequencing_platform": "/platform-terms/EFO_0010963/",
            "status": "preview",
            "submitted_file_name": "/project/GCRB/Hon_lab/shared/data/sequencing_data/2023/2023-03-24-McDermott-NextSeq.10X/2023-03-24/outs/fastq_path/AAC235NHV/LW234B-2_S4_L001_R1_001.fastq.gz",
            "upload_status": "validated"
        },
        {
            "@id": "/sequence-files/IGVFFI9083IKUZ/",
            "accession": "IGVFFI9083IKUZ",
            "aliases": [
                "gary-hon:LW234B-2_2_R1"
            ],
            "content_type": "reads",
            "controlled_access": false,
            "creation_timestamp": "2024-02-21T18:25:33.830845+00:00",
            "file_format": "fastq",
            "file_size": 1020512811,
            "href": "/sequence-files/IGVFFI9083IKUZ/@@download/IGVFFI9083IKUZ.fastq.gz",
            "s3_uri": "s3://igvf-files/2024/02/21/98086b6e-0998-41d6-a251-0cf70d138373/IGVFFI9083IKUZ.fastq.gz",
            "sequencing_platform": "/platform-terms/EFO_0010963/",
            "status": "preview",
            "submitted_file_name": "/project/GCRB/Hon_lab/shared/data/sequencing_data/2023/2023-03-24-McDermott-NextSeq.10X/2023-03-24/outs/fastq_path/AAC235NHV/LW234B-2_S4_L002_R1_001.fastq.gz",
            "upload_status": "validated"
        },
        {
            "@id": "/sequence-files/IGVFFI8490GAUK/",
            "accession": "IGVFFI8490GAUK",
            "aliases": [
                "gary-hon:LW234B-2_1_I2"
            ],
            "content_type": "reads",
            "controlled_access": false,
            "creation_timestamp": "2024-02-21T18:24:42.339197+00:00",
            "file_format": "fastq",
            "file_size": 382378133,
            "href": "/sequence-files/IGVFFI8490GAUK/@@download/IGVFFI8490GAUK.fastq.gz",
            "s3_uri": "s3://igvf-files/2024/02/21/30c9fba0-e7c7-4b03-a91a-8d0d155d68e3/IGVFFI8490GAUK.fastq.gz",
            "sequencing_platform": "/platform-terms/EFO_0010963/",
            "status": "preview",
            "submitted_file_name": "/project/GCRB/Hon_lab/shared/data/sequencing_data/2023/2023-03-24-McDermott-NextSeq.10X/2023-03-24/outs/fastq_path/AAC235NHV/LW234B-2_S4_L001_I2_001.fastq.gz",
            "upload_status": "validated"
        },
        {
            "@id": "/sequence-files/IGVFFI6705RMUI/",
            "accession": "IGVFFI6705RMUI",
            "aliases": [
                "gary-hon:LW234B-2_2_I2"
            ],
            "content_type": "reads",
            "controlled_access": false,
            "creation_timestamp": "2024-02-21T18:25:26.663669+00:00",
            "file_format": "fastq",
            "file_size": 347095793,
            "href": "/sequence-files/IGVFFI6705RMUI/@@download/IGVFFI6705RMUI.fastq.gz",
            "s3_uri": "s3://igvf-files/2024/02/21/2bffebc6-1169-43e5-95e1-085bd22dacff/IGVFFI6705RMUI.fastq.gz",
            "sequencing_platform": "/platform-terms/EFO_0010963/",
            "status": "preview",
            "submitted_file_name": "/project/GCRB/Hon_lab/shared/data/sequencing_data/2023/2023-03-24-McDermott-NextSeq.10X/2023-03-24/outs/fastq_path/AAC235NHV/LW234B-2_S4_L002_I2_001.fastq.gz",
            "upload_status": "validated"
        },
        {
            "@id": "/sequence-files/IGVFFI2829XKCE/",
            "accession": "IGVFFI2829XKCE",
            "aliases": [
                "gary-hon:LW234B-2_1_I1"
            ],
            "content_type": "reads",
            "controlled_access": false,
            "creation_timestamp": "2024-02-21T18:24:35.114092+00:00",
            "file_format": "fastq",
            "file_size": 361844130,
            "href": "/sequence-files/IGVFFI2829XKCE/@@download/IGVFFI2829XKCE.fastq.gz",
            "s3_uri": "s3://igvf-files/2024/02/21/83a17b29-e715-47dc-b172-b85fca9e9dab/IGVFFI2829XKCE.fastq.gz",
            "sequencing_platform": "/platform-terms/EFO_0010963/",
            "status": "preview",
            "submitted_file_name": "/project/GCRB/Hon_lab/shared/data/sequencing_data/2023/2023-03-24-McDermott-NextSeq.10X/2023-03-24/outs/fastq_path/AAC235NHV/LW234B-2_S4_L001_I1_001.fastq.gz",
            "upload_status": "validated"
        },
        {
            "@id": "/sequence-files/IGVFFI1008SZVT/",
            "accession": "IGVFFI1008SZVT",
            "aliases": [
                "gary-hon:LW234B-2_1_R2"
            ],
            "content_type": "reads",
            "controlled_access": false,
            "creation_timestamp": "2024-02-21T18:25:03.211315+00:00",
            "file_format": "fastq",
            "file_size": 1441937177,
            "href": "/sequence-files/IGVFFI1008SZVT/@@download/IGVFFI1008SZVT.fastq.gz",
            "s3_uri": "s3://igvf-files/2024/02/21/d7a1ecf0-6dfc-4304-90ef-7c0df2bdffd3/IGVFFI1008SZVT.fastq.gz",
            "sequencing_platform": "/platform-terms/EFO_0010963/",
            "status": "preview",
            "submitted_file_name": "/project/GCRB/Hon_lab/shared/data/sequencing_data/2023/2023-03-24-McDermott-NextSeq.10X/2023-03-24/outs/fastq_path/AAC235NHV/LW234B-2_S4_L001_R2_001.fastq.gz",
            "upload_status": "validated"
        },
        {
            "@id": "/sequence-files/IGVFFI0084VSYK/",
            "accession": "IGVFFI0084VSYK",
            "aliases": [
                "gary-hon:LW234B-2_2_I1"
            ],
            "content_type": "reads",
            "controlled_access": false,
            "creation_timestamp": "2024-02-21T18:25:19.583282+00:00",
            "file_format": "fastq",
            "file_size": 335620018,
            "href": "/sequence-files/IGVFFI0084VSYK/@@download/IGVFFI0084VSYK.fastq.gz",
            "s3_uri": "s3://igvf-files/2024/02/21/996b232e-2376-4277-86ba-09b17b3a3b71/IGVFFI0084VSYK.fastq.gz",
            "sequencing_platform": "/platform-terms/EFO_0010963/",
            "status": "preview",
            "submitted_file_name": "/project/GCRB/Hon_lab/shared/data/sequencing_data/2023/2023-03-24-McDermott-NextSeq.10X/2023-03-24/outs/fastq_path/AAC235NHV/LW234B-2_S4_L002_I1_001.fastq.gz",
            "upload_status": "validated"
        },
        {
            "@id": "/sequence-files/IGVFFI5975FQYH/",
            "accession": "IGVFFI5975FQYH",
            "aliases": [
                "gary-hon:LW234B-2_2_R2"
            ],
            "content_type": "reads",
            "controlled_access": false,
            "creation_timestamp": "2024-02-21T18:25:46.852889+00:00",
            "file_format": "fastq",
            "file_size": 1317484746,
            "href": "/sequence-files/IGVFFI5975FQYH/@@download/IGVFFI5975FQYH.fastq.gz",
            "s3_uri": "s3://igvf-files/2024/02/21/a54c0184-f884-4f97-9c55-c2c4633f9a03/IGVFFI5975FQYH.fastq.gz",
            "sequencing_platform": "/platform-terms/EFO_0010963/",
            "status": "preview",
            "submitted_file_name": "/project/GCRB/Hon_lab/shared/data/sequencing_data/2023/2023-03-24-McDermott-NextSeq.10X/2023-03-24/outs/fastq_path/AAC235NHV/LW234B-2_S4_L002_R2_001.fastq.gz",
            "upload_status": "validated"
        }
    ],
    "input_for": [
        "/analysis-sets/IGVFDS9192YMGI/"
    ],
    "lab": {
        "@id": "/labs/gary-hon/",
        "title": "Gary Hon, UT"
    },
    "measurement_sets": [
        {
            "@id": "/measurement-sets/IGVFDS8705MRYI/",
            "accession": "IGVFDS8705MRYI",
            "aliases": [
                "gary-hon:CM_Pilot_2_PB_RNA_LW234"
            ],
            "preferred_assay_title": "Perturb-seq",
            "status": "preview"
        }
    ],
    "samples": [
        {
            "@id": "/in-vitro-systems/IGVFSM8137TZJW/",
            "@type": [
                "InVitroSystem",
                "Biosample",
                "Sample",
                "Item"
            ],
            "accession": "IGVFSM8137TZJW",
            "aliases": [
                "nikhil-munshi:differentited_WTC11_CM_Pilot1_PB_LW234"
            ],
            "classifications": [
                "differentiated cell specimen"
            ],
            "construct_library_sets": [
                "/construct-library-sets/IGVFDS9629YZLO/"
            ],
            "modifications": [
                {
                    "@id": "/crispr-modifications/0a63b754-eca4-44aa-bbc2-fccdc6c44fb5/",
                    "modality": "interference",
                    "status": "preview"
                }
            ],
            "sample_terms": [
                {
                    "@id": "/sample-terms/EFO_0009747/",
                    "@type": [
                        "SampleTerm",
                        "OntologyTerm",
                        "Item"
                    ],
                    "aliases": [
                        "igvf:WTC11"
                    ],
                    "status": "released",
                    "summary": "GM25256 (WTC-11)",
                    "term_name": "GM25256 (WTC-11)"
                }
            ],
            "status": "preview",
            "summary": "GM25256 (WTC-11) differentiated cell specimen induced to cardiac muscle cell for 12 days (cellular sub pool: subpool_LW264), male, Homo sapiens modified with CRISPRi Sp-dCas9, transfected with a guide library",
            "targeted_sample_term": {
                "@id": "/sample-terms/CL_0000746/",
                "status": "released",
                "term_name": "cardiac muscle cell"
            },
            "taxa": "Homo sapiens"
        }
    ],
    "schema_version": "12",
    "status": "preview",
    "submitted_by": {
        "@id": "/users/b05645f1-2d56-4a5e-b272-4601e555a3fa/",
        "title": "Mpathi Nzima"
    },
    "submitted_files_timestamp": "2024-02-21T18:24:35.114092+00:00",
    "summary": "gRNA sequencing for CRISPR interference Perturb-seq integrating a guide (sgRNA) library targeting accessible genome regions in many genomic loci",
    "uuid": "3568b68b-59d7-4afa-9edf-ebeddb34c283"
}